Guest guest Posted April 22, 2011 Report Share Posted April 22, 2011 I just need to clarify what benefit LDN offers, in my head, to decide whether it should be of benefit to me. So I am thinking aloud here. If what am saying is correct, can someone please tell me? Thanks. It seems that the human brain/body manufactures a pre determined number of endorphins daily. They are generally made at night whilst we are sleeping, EXCEPT in certain situations, such as vigorous exercise, fear, intense excitement, orgasm, chocolate/comfort food consumption. What we make during the day is included in the total amount of what we are programmed to manufacture, therefore a normal person would make less at night if he made them during the day. The euphoria one feels when one gets an endorphin rush happens when they are manufactured, not when endorphins, manufactured at night, are used to provide us with energy, confidence, or to boost our immune system. So the purpose of LDN is to make us manufacture the endorphins during the day, rater than at night, so that we can actually FEEL their benefit. Is this right, what I am saying? Maree Melbourne, AUSTRALIA Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 22, 2011 Report Share Posted April 22, 2011 Mechanisms involved in beneficial effect of LDN http://preview.tinyurl.com/lelnlu > > > I just need to clarify what benefit LDN offers, in my head, to decide > whether it should be of benefit to me. So I am thinking aloud here. If > what am saying is correct, can someone please tell me? Thanks. > > It seems that the human brain/body manufactures a pre determined number of > endorphins daily. They are generally made at night whilst we are sleeping, > EXCEPT in certain situations, such as vigorous exercise, fear, intense > excitement, orgasm, chocolate/comfort food consumption. > What we make during the day is included in the total amount of what we are > programmed to manufacture, therefore a normal person would make less at > night if he made them during the day. > The euphoria one feels when one gets an endorphin rush happens when they are > manufactured, not when endorphins, manufactured at night, are used to > provide us with energy, confidence, or to boost our immune system. > So the purpose of LDN is to make us manufacture the endorphins during the > day, rater than at night, so that we can actually FEEL their benefit. > > Is this right, what I am saying? > > Maree > Melbourne, AUSTRALIA > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 22, 2011 Report Share Posted April 22, 2011 I'm not a professional here, being a newbie and all, but I know there is actually a whole lot more going on than just an endorphin rush. The body does make more at night, but LDN blocks receptors which trigger the body to make more than normal, but only for a short time. It also increases the numbers of receptors on new cells that are created, normalized white blood cells, and there is something about free radicals?? It can definitely help with depression also. There is a short LDN film that I learned a lot from...I'll try to find the link and send it along. Some people here have it in their signature so it can be shared easily. What are you looking to treat (which disease)? That might help the folks here point you in the right direction. Niki On Fri, Apr 22, 2011 at 3:30 AM, Maree WRAGG <mwragg@...> wrote: I just need to clarify what benefit LDN offers, in my head, to decidewhether it should be of benefit to me. So I am thinking aloud here. Ifwhat am saying is correct, can someone please tell me? Thanks. It seems that the human brain/body manufactures a pre determined number ofendorphins daily. They are generally made at night whilst we are sleeping,EXCEPT in certain situations, such as vigorous exercise, fear, intense excitement, orgasm, chocolate/comfort food consumption.What we make during the day is included in the total amount of what we areprogrammed to manufacture, therefore a normal person would make less atnight if he made them during the day. The euphoria one feels when one gets an endorphin rush happens when they aremanufactured, not when endorphins, manufactured at night, are used toprovide us with energy, confidence, or to boost our immune system. So the purpose of LDN is to make us manufacture the endorphins during theday, rater than at night, so that we can actually FEEL their benefit.Is this right, what I am saying?MareeMelbourne, AUSTRALIA -- R. Gagnon87 Westbrook Rd.RR WhatelySouth Deerfield MA 01373413-325-7448 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 22, 2011 Report Share Posted April 22, 2011 http://www.youtube.com/watch?v=xr-n8jMLenU & feature=related On Fri, Apr 22, 2011 at 3:30 AM, Maree WRAGG <mwragg@...> wrote: I just need to clarify what benefit LDN offers, in my head, to decidewhether it should be of benefit to me. So I am thinking aloud here. Ifwhat am saying is correct, can someone please tell me? Thanks. It seems that the human brain/body manufactures a pre determined number ofendorphins daily. They are generally made at night whilst we are sleeping,EXCEPT in certain situations, such as vigorous exercise, fear, intense excitement, orgasm, chocolate/comfort food consumption.What we make during the day is included in the total amount of what we areprogrammed to manufacture, therefore a normal person would make less atnight if he made them during the day. The euphoria one feels when one gets an endorphin rush happens when they aremanufactured, not when endorphins, manufactured at night, are used toprovide us with energy, confidence, or to boost our immune system. So the purpose of LDN is to make us manufacture the endorphins during theday, rater than at night, so that we can actually FEEL their benefit.Is this right, what I am saying?MareeMelbourne, AUSTRALIA -- R. Gagnon87 Westbrook Rd.RR WhatelySouth Deerfield MA 01373413-325-7448 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 22, 2011 Report Share Posted April 22, 2011 Sort of Maree, here is an explanation - Previous orthodoxy had it that autoimmune diseases were the result of an overactive immune system attacking its own body, but newer research suggests that it is a weakened immune system at the root of so many immune disorders. To that new research LDN adds valuable evidence of support in that the numbers of endorphins and enkephalins, opioid peptides which are components of immune cells, are greatly increased with the use of LDN. These opioid peptides are expressed, contained, and released by immune cells and the more there are available in the body, the stronger, more effective, and well-regulated the immune system is. It goes without saying that, if autoimmune diseases result from a weakened immune system, this immune strengthening can be a great boon to the quality of life and survivability of those suffering from immune related disorders including cancer as mentioned above. The specific mechanism by which greater levels of opioid peptides are produced is by the antagonist characteristics of naltrexone. In high doses, 50 mg to 300 mg, it blockades the opioid receptors of the immune system, shutting it down for all intents and purposes. In low doses, 4.5 mg or less, naltrexone blockades these receptors for only a short time, four to six hours, thus "tricking" the body into "thinking" there are not enough endorphins and enkaphalins available to combine with the receptors. This triggers the natural response of the body to overcome the perceived deficit by over-producing these opioid peptides for a period of time following the brief blockade, thus strengthening immune function and providing the specific peptide, [met5]enkephalin, necessary to form the OGF/OGFr axis. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 22, 2011 Report Share Posted April 22, 2011 When our doctor explained LDN to us, he said, "It neither stimulates nor suppresses the immune system, but balances it." Annette Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 22, 2011 Report Share Posted April 22, 2011 On Fri, 22 Apr 2011 03:30:43 -0400, Maree WRAGG <mwragg@...> wrote: > > I just need to clarify what benefit LDN offers, in my head, to decide > whether it should be of benefit to me. So I am thinking aloud here. If > what am saying is correct, can someone please tell me? Thanks. > > It seems that the human brain/body manufactures a pre determined number > of > endorphins daily. They are generally made at night whilst we are > sleeping, > EXCEPT in certain situations, such as vigorous exercise, fear, intense > excitement, orgasm, chocolate/comfort food consumption. > What we make during the day is included in the total amount of what we > are > programmed to manufacture, therefore a normal person would make less at > night if he made them during the day. > The euphoria one feels when one gets an endorphin rush happens when they > are > manufactured, not when endorphins, manufactured at night, are used to > provide us with energy, confidence, or to boost our immune system. > So the purpose of LDN is to make us manufacture the endorphins during the > day, rater than at night, so that we can actually FEEL their benefit. > > Is this right, what I am saying? > > Maree > Melbourne, AUSTRALIA > > No, not exactly. If you have an auto-immune disease your body will not produce enough endorphins, and your level of endorphins is, therefore, low. And so is your energy level. But endorphins have many other beneficial effects on the body as a whole and on the immune system. LDN forces the body to produce more endorphins. And not only more endorphins, but more endorphin receptors. Which is exactly what you need for a healthier immune system which will combat any number of diseases/conditions that result from immune dysfunction, including IBDs, MS, various cancers, allergies, arthritis, and a host of others. n Quote Link to comment Share on other sites More sharing options...
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