Re: Starting LDN Exhausted/more pain

[Guest guest]

My friend with MS says LDN has made a remarkable difference in her life. However, she said it took about 3 weeks to adjust to the medication.

Below is a YouTube video/journal of 's experience on LDN.

http://www.youtube.com/watch?v=Y4JKhiNBimM & feature=related

AKB

[Guest guest]

From my experience of reading the postings here (and with friends) many folks with fibro seem to be very medication sensitive.  You may need to titrate up.  Starting even as low as 1 mg.

 

The easiest way to convert your capsules to liquid and titratable dosing ...

 

Do a 1:1 ration - soooo .... 4.5 ml of distilled water - throw in capsule - now 1 ml of solution equals 1 mg of LDN.

 

4.5 ml is not very much liquid though so you may want to do up several at once.  Say 18 ml distilled water - 4 capsules - in a tinted glass bottle - stored in fridge.  That would give you 18 days worth at 1 mg per dose.  Stick with 1 mg for a week or more depending on how you feel, up it in .5 to 1 mg increments staying at each dose at least a week, longer if you need the adjustment time.

 

Just my 2 cents.  I was lucky and was able to tolerate 4.5 mg from go.

 

Jaxi

On Thu, Apr 21, 2011 at 3:31 PM, mp <mpedestrian@...> wrote:

Ive been looking forward to starting LDN for months.  My son, with autism, tried it and we saw incredible gains, reduced tantrums anxiety, better mood, more focused, scripting turned to paraphrasing, potty trained over night...  I was expecting a lot for myself after having seen such amazing things for my son.

I have fibromayalgia, frequent back/neck pain, headaches, anxiety, depression, real big mood swings, fatigue, brain fog...etc.I started LDN 4 days ago.  4.5mg at night.  I am sleeping like I'm drugged, waking up exhausted, needing a big nap, more brain fog, more fatigue/exhaustion, more mood swings, more pain.  I know that I am very sensitive to medicines some times (when I tried to start Cymbalta I had a similar experience and did not continue it as it was just too difficult), does this maybe mean that I am at too high of a dosage, or is this a getting used to it period where the body just needs to adjust for a few weeks.  I will stick it out if it is an adjustment period, but really wonder if I should reduce the amount.

That being said if I do reduce the amount, do I just pour a capsule (its compounded) in water and then drink half the water... would the other half be good still the following night if I did this?The doc I had perscribe this doesn't really know much about it, so I thought I would ask here.

Thanks

[Guest guest]

thank you. I just had the exact same experience. started ldn 6 days ago and feel like I smoked a joint all day long. Big brain fog and unfortunately none of my sx's have gone away. I guess I was hoping for more immediate as well.I will try this diluting solution and see what happens. Don't want to give up yet!SallySally , Certified Acupressure Therapist, Health Counselorsally@...www.acupressuretherapy.net(415)420-4358

--- Re: [low dose naltrexone] Starting LDN Exhausted/more pain

From: jaxi <jaxi.schulz@...>

Date: Thu, April 21, 2011 5:09 pm

mp <mpedestrian@...>

Cc: low dose naltrexone

From my experience of reading the postings here (and with friends) many folks with fibro seem to be very medication sensitive. You may need to titrate up. Starting even as low as 1 mg. The easiest way to convert your capsules to liquid and titratable dosing ... Do a 1:1 ration - soooo .... 4.5 ml of distilled water - throw in capsule - now 1 ml of solution equals 1 mg of LDN. 4.5 ml is not very much liquid though so you may want to do up several at once. Say 18 ml distilled water - 4 capsules - in a tinted glass bottle - stored in fridge. That would give you 18 days worth at 1 mg per dose. Stick with 1 mg for a week or more depending on how you feel, up it in .5 to 1 mg increments staying at each dose at least a week, longer if you need the adjustment time. Just my 2 cents. I was lucky and was able to tolerate 4.5 mg from go. Jaxi On Thu, Apr 21, 2011 at 3:31 PM, mp <mpedestrian@...> wrote: Ive been looking forward to starting LDN for months. My son, with autism, tried it and we saw incredible gains, reduced tantrums anxiety, better mood, more focused, scripting turned to paraphrasing, potty trained over night... I was expecting a lot for myself after having seen such amazing things for my son. I have fibromayalgia, frequent back/neck pain, headaches, anxiety, depression, real big mood swings, fatigue, brain fog...etc.I started LDN 4 days ago. 4.5mg at night. I am sleeping like I'm drugged, waking up exhausted, needing a big nap, more brain fog, more fatigue/exhaustion, more mood swings, more pain. I know that I am very sensitive to medicines some times (when I tried to start Cymbalta I had a similar experience and did not continue it as it was just too difficult), does this maybe mean that I am at too high of a dosage, or is this a getting used to it period where the body just needs to adjust for a few weeks. I will stick it out if it is an adjustment period, but really wonder if I should reduce the amount. That being said if I do reduce the amount, do I just pour a capsule (its compounded) in water and then drink half the water... would the other half be good still the following night if I did this?The doc I had perscribe this doesn't really know much about it, so I thought I would ask here. Thanks

[Guest guest]

Yes, people with fibro, and some other people as well, really need to start

low and move up slowly. I have fibro, and started at 3mg and eventually

went up to 4.5mg and did fine, but I have come to the conclusion, based on

posts here, that so many people with fibro are ultrasensitive to any

changes, not just drugs or supplements but anything at all, that it's best

to just start slow. Because if you're not one of the lucky ones that can

handle it easily, it can be so discouraging and even scary.

I really think that the www.ldninfo.org and related websites should add a

caution up front, along with the other cautions, that people with fibro

should start at the most 1.5mg, so that fibro folks would be notified early

on to start low and go slow.

Since you've already started at a higher dose, might want to give it a rest

for a couple of days, then come back to it at the low dose and work up.

--

>thank you. I just had the exact same experience. started ldn 6 days ago

>and feel like I smoked a joint all day long. Big brain fog and

>unfortunately none of my sx's have gone away. I guess I was hoping for

>more immediate as well.

>I will try this diluting solution and see what happens. Don't want to give

>up yet!

>

>Sally

>

>Sally , Certified Acupressure Therapist, Health Counselor

><mailto:sally@...>sally@...

>www.acupressuretherapy.net

>(415)420-4358

>

>

>--- Re: [low dose naltrexone] Starting LDN Exhausted/more pain

>From: jaxi <<http://jaxi.schulzgmail>>jaxi.schulz@... & gt;

>Date: Thu, April 21, 2011 5:09 pm

>mp <<mailto:mpedestrian@...>mpedestrian@...>

>Cc:

><mailto:low dose naltrexone >low dose naltrexone

>

>

> From my experience of reading the postings here (and with friends) many

> folks with fibro seem to be very medication sensitive. You may need to

> titrate up. Starting even as low as 1 mg.

>

>The easiest way to convert your capsules to liquid and titratable dosing ...

>

>Do a 1:1 ration - soooo .... 4.5 ml of distilled water - throw in capsule

>- now 1 ml of solution equals 1 mg of LDN.

>

>4.5 ml is not very much liquid though so you may want to do up several at

>once. Say 18 ml distilled water - 4 capsules - in a tinted glass bottle -

>stored in fridge. That would give you 18 days worth at 1 mg per

>dose. Stick with 1 mg for a week or more depending on how you feel, up it

>in .5 to 1 mg increments staying at each dose at least a week, longer if

>you need the adjustment time.

>

>Just my 2 cents. I was lucky and was able to tolerate 4.5 mg from go.

>

>Jaxi

>

>On Thu, Apr 21, 2011 at 3:31 PM, mp

><<mailto:mpedestrian@...>mpedestrian@...> wrote:

>Ive been looking forward to starting LDN for months. My son, with autism,

>tried it and we saw incredible gains, reduced tantrums anxiety, better

>mood, more focused, scripting turned to paraphrasing, potty trained over

>night... I was expecting a lot for myself after having seen such amazing

>things for my son.

>

>I have fibromayalgia, frequent back/neck pain, headaches, anxiety,

>depression, real big mood swings, fatigue, brain fog...etc.

>

>I started LDN 4 days ago. 4.5mg at night. I am sleeping like I'm

>drugged, waking up exhausted, needing a big nap, more brain fog, more

>fatigue/exhaustion, more mood swings, more pain. I know that I am very

>sensitive to medicines some times (when I tried to start Cymbalta I had a

>similar experience and did not continue it as it was just too difficult),

>does this maybe mean that I am at too high of a dosage, or is this a

>getting used to it period where the body just needs to adjust for a few

>weeks. I will stick it out if it is an adjustment period, but really

>wonder if I should reduce the amount.

>

>That being said if I do reduce the amount, do I just pour a capsule (its

>compounded) in water and then drink half the water... would the other half

>be good still the following night if I did this?

>

>The doc I had perscribe this doesn't really know much about it, so I

>thought I would ask here.

>

>Thanks

>

>

>

>

>

>

~~~ There is no way to peace; peace is the way ~~~~

--A.J. Muste

[Guest guest]

That particular link goes to an earlier point in your friend's

journey. Here is the link to the vid at the 3 week point when she was very

positive and happy about the LDN:

http://www.youtube.com/watch?v=7XHcQqCItvc & feature=related

--V

At 03:54 PM 4/21/2011, you wrote:

>My friend with MS says LDN has made a remarkable difference in her life.

>However, she said it took about 3 weeks to adjust to the medication.

>

>Below is a YouTube video/journal of 's experience on LDN.

><http://www.youtube.com/watch?v=Y4JKhiNBimM & feature=related>http://www.youtube.\

com/watch?v=Y4JKhiNBimM & feature=related

>

>

>AKB

>

>

>

~~~ There is no way to peace; peace is the way ~~~~

--A.J. Muste

[Guest guest]

You must check your thyroid.there is almost always

connection ,fibro thyroid and also depression.

Hypothyroidism:

The Unsuspected Illness

Hypothyroidism

Type 2: The Epidemic

I am using the Free version of SPAMfighter.SPAMfighter has removed 3394 of my spam emails to date.Do you have a slow PC? Try free scan!

[Guest guest]

I am also experiencing the side effect of difficulty waking up in the morning. It is like I am drugged. I take ldn about 9:30 each night, just before my head hits the pillow, and my husband cannot wake me at 8am. And when I finally do get up it feels like I have been drugged. I am on my fourth week of ldn. First two weeks at 1mg, second two weeks at 2mg, etc. So I am starting out extremely slow.The pharmacy said they use lactose for filler. I don't see a problem with that.But I am getting worse, spending most days in bed now, very tired. I plan on giving ldn six weeks, but don't know if I can go on like this. Cheryl cday@..."Life isn't about waiting for the storm to pass. It's about learning to dance in the rain."

[Guest guest]

On Fri, 22 Apr 2011 13:16:07 -0400, Cheryl Day <cday@...> wrote:

> I am also experiencing the side effect of difficulty waking up in the

> morning. It is like I am drugged. I take ldn about 9:30 each night,

> just before my head hits the pillow, and my husband cannot wake me at

> 8am. And when I finally do get up it feels like I have been drugged.

>

> I am on my fourth week of ldn. First two weeks at 1mg, second two

> weeks at 2mg, etc. So I am starting out extremely slow.

>

> The pharmacy said they use lactose for filler. I don't see a problem

> with that.

What are you taking the LDN for? If you have a digestive disease, clearly

lactose COULD be a problem. And it MIGHT be even if you're taking it for

some other reason.

Personally, on renewing the prescription I'd ask for a different filler.

I had that kind of reaction to LDN initially, but it went away within a

week. Can't speak to what might cause the drugged feeling.

n

[Guest guest]

I would suggest that increasing your dose when you had not adjusted to the previous dose was not a good idea.  Stay at 1 mg until you adjust to it - ie - no longer experience the drugged morning feeling - then in crease by .5 mg - hopefully with the increases any new adjustment period will be shorter and issues less significant.  You sound like perhaps you are using it for fibro?  At the least you sound medication sensitive.

JaxiOn Fri, Apr 22, 2011 at 12:16 PM, Cheryl Day <cday@...> wrote:

I am also experiencing the side effect of difficulty waking up in the morning. It is like I am drugged. I take ldn about 9:30 each night, just before my head hits the pillow, and my husband cannot wake me at 8am. And when I finally do get up it feels like I have been drugged. 

I am on my fourth week of ldn. First two weeks at 1mg, second two weeks at 2mg, etc. So I am starting out extremely slow.The pharmacy said they use lactose for filler. I don't see a problem with that.

But I am getting worse, spending most days in bed now, very tired. I plan on giving ldn six weeks, but don't know if I can go on like this.

Cheryl cday@... " Life isn't about waiting for the storm to pass.  It's about learning to dance in the rain. "

[Guest guest]

hi cheryl - try morning dose, not a written rule that you must take at night

regards/peter/london/ppms

From: Cheryl Day <cday@...>low dose naltrexone Sent: Friday, 22 April 2011, 18:16Subject: [low dose naltrexone] Re: Starting LDN Exhausted/more pain

I am also experiencing the side effect of difficulty waking up in the morning. It is like I am drugged. I take ldn about 9:30 each night, just before my head hits the pillow, and my husband cannot wake me at 8am. And when I finally do get up it feels like I have been drugged.

I am on my fourth week of ldn. First two weeks at 1mg, second two weeks at 2mg, etc. So I am starting out extremely slow.

The pharmacy said they use lactose for filler. I don't see a problem with that.

But I am getting worse, spending most days in bed now, very tired. I plan on giving ldn six weeks, but don't know if I can go on like this.

Cheryl

cday@...

"Life isn't about waiting for the storm to pass. It's about learning to dance in the rain."