guggul

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Name: GuggulBiological Name: Commiphora mukulOther Names: Gugulipid,

Mukul myrrh tree, Gugul Lipid, guggal, guggulParts Used: gum resinActive

Compounds:  

Ketone fraction that is extracted from the resin contains the most

potent cholesterol lowering components. This is composed of C21 or C27

steroids, with the major components being Z- and E-guggulsterone.

Guggul contains resin, volatile oils, and gum. The extract isolates

ketonic steroid compounds known as guggulsterones. These compounds have

been shown to provide the lipid-lowering actions noted for guggul.

Guggul significantly lowers serum triglycerides and cholesterol as well

as LDL and VLDL cholesterols (the " bad " cholesterols). At the same time,

it raises levels of HDL cholesterol (the " good " cholesterol). Guggul has

also been shown to reduce the stickiness of platelets-another effect

that lowers the risk of coronary artery disease.

History:

Guggul is a highly valued botanical medicine used in Ayurveda, Indian

system of medicine. It is used for rheumatoid arthritis, and lipid

disorders. The classic Ayurveda medical text, the Sushruta samhita,

described in detail the usefulness of this herb for treatment of obesity

and other disorders of fat, including " coating and obstruction of

channels " .

Encouraged by the Ayurvedic description of this herb for lowering

cholesterol, scientists have conducted clinical trials to test the

effectiveness of this herb in disorders of lipid metabolism and for

lowering weight. The research resulted in the development of a natural

cholesterol lowering substance that is safer and more effective than

many cholesterol-lowering drugs. Gugulipid was granted approval in India

for marketing as a lipid lowering drug in 1986.

Remedies For: 

Key uses:

High cholesterol levels

High triglyceride levels

Guglipid offers considerable benefit in preventing and treating

atherosclerotic vascular disease (Heart disease). It is most effective

in lowering LDL cholesterol and triglycerides.It also raises the level

of good cholesterol (HDL).

Guggul exhibits a cholesterol lowering ability unlike any other natural

substance. In human trials, using gugulipid, the cholesterol levels

dropped 14 to 27 percent in a 4 to 12 week period while the triglyceride

levels dropped from 22 to 30 percent. This guggul has great effect in

preventing heart atherosclerosis, or narrowing of the arteries.

Description:

Guglipid is derived from the mukul myrrh tree, a small thorny tree 4 to

6 feet tall, that is native to Arabia and India. The tree remains

without any foliage for most of the year. It has ash colored bark, and

comes off in rough flakes, exposing the underbark, which also peels off.

The tree exudes a yellowish resin called gum guggul or guggulu, that has

a balsamic odor. This resin is used for medicinal purposes.

Dosage:

Daily recommendations for guggul are typically based on the amount of

guggulsterones in the extract. A common intake of guggulsterones is 25

mg three times per day. Most extracts contain 5-10% guggulsterones. For

a 5 percent guggulsterone extract, this translates to an effective dose

of 500 milligrams three times per day. Many people take the extracts

daily for twelve to twenty-four weeks.

Safety:

Part of the resin from which the medicinal extract is made is toxic and,

hence, the raw resin should not be used for any treatment.

Early studies with the crude oleoresin reported numerous side effects,

including diarrhea, anorexia, abdominal pain, and skin rash. Modern

extracts are more purified, and far fewer side effects (e.g., mild

abdominal discomfort) have been reported with long-term use. Gugglipid,

the standardized extract has better chemical efficacy and is better

tolerated by patients. Animal studies indicate that this material is not

toxic. It is also believed safe to use during pregnancy. (With your

physician's supervision). The extract has not shown any adverse side

effects, nor it has affected the liver function, blood sugar control,

kidney function, or hematological parameters.

Guggul should be used with caution by persons with liver disease and in

cases of inflammatory bowel disease and diarrhea. A physician should be

consulted for any case of elevated cholesterol and/or triglycerides

Love,

Reneé and Jerry

rja86@...