Urso and other liver diseases

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++This is a page from the site sent in by Joan of London, great news!

Thanks Joan!!! ++++++

NEW DATA ON AXCAN'S URSO® Immunological effect could prove beneficial for

other liver diseases

MONT-SAINT-HILAIRE, QUEBEC - Investigators from the Mayo Clinic, the

Sunnybrook Hospital and the Department of Pharmacology of the University of

Toronto have presented data on the effect of ursodeoxycholic acid (URSO®)

treatment on serum cytokines in patients with primary biliary cirrhosis

(PBC). This study has shown that a two-year treatment with URSO® can

significantly decrease (p<0,05) serum levels of Tumor Necrosis Factor (TNF)

in PBC patients. .

" These results are important in our understanding of URSO®’s mechanism of

action, » said Dr. François , Axcan’s Vice-President, Scientific

Affairs. " These new findings are very exciting since they confirm that URSO®

have intrinsic immunomodulating properties and this could partially explain

its beneficial effects in PBC and other liver diseases " he added.

Axcan is continuing its development program to obtain FDA approval for other

indications for URSO®, including prevention of the recurrence of colorectal

polyps, hypercholesterolemia, primary sclerosing cholangitis, and

non-alcoholic steatohepatitis. <A

HREF= " http://www.axcan.com/axcan/english/index.html " >Axcan Pharma Inc.</A>

http://www.axcan.com/axcan/english/index.html