RE: Re: how to test a celiac's baby for potential CD?

[Guest guest]

LabCorp

is a CLIA-certified lab which does offer several celiac tests. As such, it

should be fine to use this lab. I checked their website -- be sure that the

test ordered is 167082, Celiac Disease HLA DQ Association.

It’s not clear from their website whether they will

test with any more detail than just DQ2 and DQ8, but you could ask them. Here’s

the web page with information about this test, including a phone number: https://www.labcorp.com/wps/portal/!ut/p/c1/04_SB8K8xLLM9MSSzPy8xBz9CP0os_hACzO_QCM_IwMLXyM3AyNjMycDU2dXQwN3M6B8JG55AwMCusNB9uHXD5I3wAEcDfT9PPJzU_Uj9aPM40NdTYINPS2NDfxd3Q0MjMw9fTwtLfwNDYwN9UP0C3IjDLJMIhUB94XRqA!!/dl2/d1/L0lDU0lKSmdvS1VRIS9JSFNBQ0lpTXlDb3FiRURBSUEhIS9ZQTQ1NDUwLTVGMHN0eWp3LzdfVUU0UzFJOTMwT0VHMDAyN0lMSTk4TzEwMzEvSzNyX18xMjMvc3BmX0FjdGlvbk5hbWUvc3BmX0FjdGlvbkxpc3RlbmVy/?testId=407634 & spf_strutsAction=!2fshowDetail.do

For a comparison, take a look at Kimball Labs website: http://www.kimballgenetics.com/tests-celiacdisease.html ,

which describes in much more detail what they are testing when they do celiac

DNA testing, and tells what kind of information and interpretation they will

provide with the results. You could ask LabCorp if they do what Kimball’s

site says Kimball does. Kimball has genetic counselors who will explain results

to patients, however I don’t see that LabCorp does, so another thing you

can do is ask your physician to refer you to a genetic counselor for an explanation,

if your insurance will cover that.

At any rate, in my opinion, if LabCorp is what your

insurance covers and you want DNA results, then go ahead and have your doctor

order through LabCorp. If you are not happy with the results for some reason,

you can always choose to self-pay at another time.

Hope this helps!

From:

[mailto: ] On

Behalf Of lauracgadd

Sent: Monday, July 06, 2009 10:48 AM

Subject: [ ] Re: how to test a celiac's baby for potential

CD?

Thank you to all who replied to my earlier

posting asking about how to test my 8 month old for " the gene " . One

further question: has anyone had this test run via LabCorp? They are the only

lab that my insurance will cover, so I wondered if they are viable? Or should I

pay out of pocket for one of the places Pam listed?

Thanks again!

-laura

[Guest guest]

23

and Me does not do genetic HLA-typing of your DNA. What they do is look

for SNPs, which are Single Nucleotide Polymorphisms – single base-pair

changes which are markers for changes in genes – they do not test the

actual genes themselves. For those of you who want the technical scoop, here’s

a note from their website:

“23andMe

analyzes your DNA using a genotyping chip. The chip we use is an Illumina

HumanHap550+ Genotyping BeadChip. 23andMe has also added a customized set of

SNPs to the chip.”

If

someone wants to test for the genetic HLA-types in DNA which are associated

with celiac disease, they need to use a lab which does actually test the genes

which are contributors to DNA HLA-typing. There are many CLIA-certified labs

which do this testing, several of which have been mentioned on this list lately.

If

doing a cheek swab test HLA test is important to you, go to Kimball Labs –

they do this for less than $400. You can order the kit and do it at home, then

mail it in to them. Your doctor must agree to be named on the form as well,

although he/she doesn’t need to sign it. They will mail you back the

results. It sounds like Enterolab will also do this per Luther’s note

below.

Hope

that helps,

From:

[mailto: ] On

Behalf Of edensmith13

Sent: Tuesday, July 07, 2009 8:49 AM

Subject: [ ] Re: how to test a celiac's baby for potential

CD?

I have heard of another test that was developed

by the wife of the founder of Google. It is called 23andMe. The cost used to be

over a thousand dollars, but now it is at $400.00. Time magazine did a piece on

as one of the best inventions last year. They only need a saliva swab, mail it

in and get the results. The website will have more info for you also.

Eden

>

> >

> >

> > Hi gang - I know this has been discussed on here over the years, but

I'm

> > not able to find the answer by searching the old postings. Can

someone

> > refresh my memory? Basically, I have Celiac Disease, and I have an

8.5 month

> > old baby. I have been GF for 5 years, and have kept the baby GF thus

far (my

> > breastmilk is GF and making sure the commercial baby foods I feed her

are

> > GF). In a couple days, our pediatrician will do a blood test for iron

and

> > lead, and we have talked about her also requesting tests for CD. I

know that

> > the usual ELISA/IgG and IgA tests won't work since she's not being

exposed

> > to gluten, but I'm interested in seeing if she has " the

gene " . Can someone

> > please tell me exactly what test we're supposed to ask for (even a

> > recommended lab??), and any other info about it? I read somewhere

that 35%

> > of the population may have the gene though it appears that 1 in 133

actually

> > have CD...? Any other advice? Should I pay for it out of pocket so it

won't

> > be on her medical record in case it could ruin her insurability?

> >

> > Thanks!

> > -laura

> >

> >

> >

>