Los Angeles Heath articles

[Guest guest]

Hi All, The site:

http://www.latimes.com/features/health/la-he-fast2dec02,0,1064695.story?coll

=la%2Dheadlines%2Dhealth

I thought was nice this morning.

My pick: Think a fast can give you license to feast?

For: CAPSULES New pyramid is built on disease prevention,

I attached the two important tables.

For:

SUPPLEMENTS,

I like best:

Research: There is a great deal of research underway on coenzyme Q10. So

far, the best evidence for its use is for congestive heart failure.

Cheers, A.

Alan Pater, Ph.D.; Faculty of Medicine; Memorial University; St. 's, NL

A1B 3V6 Canada; Tel. No.: (709) 777-6488; Fax No.: (709) 777-7010; email:

apater@...

TABLE 4 Relative risk (RR) and 95% CIs of major chronic disease, cardiovascular

disease (CVD), and cancer

in men according to Alternate Healthy Eating Index (AHEI) scores and Recommended

Food Scores (RFS)

Quintiles of index scores

1

2

3

4

5

P

for

trend1

Major chronic disease2

AHEI

n

704

672

634

568

541

Age-adjusted RR

1.0

0.91

(0.82,

1.01)

0.83

(0.74,

0.92)

0.72

(0.65,

0.81)

0.70

(0.63,

0.79)

<0.001

Multivariate-adjusted RR3

1.0

0.96

(0.86,

1.07)

0.88

(0.79,

0.99)

0.79

(0.71,

0.89)

0.80

(0.71,

0.91)

<0.001

RFS

n

712

665

615

510

617

Age-adjusted RR

1.0

0.90

(0.81,

1.00)

0.78

(0.70,

0.87)

0.74

(0.66,

0.83)

0.79

(0.71,

0.88)

<0.001

Multivariate-adjusted RR3

1.0

0.97

(0.87,

1.07)

0.88

(0.79,

0.97)

0.83

(0.75,

0.93)

0.93

(0.83,

1.04)

0.016

CVD4

AHEI

n

298

246

233

197

165

Age-adjusted RR

1.0

0.80

(0.68,

0.95)

0.73

(0.61,

0.87)

0.61

(0.51,

0.73)

0.52

(0.43,

0.63)

<0.001

Multivariate-adjusted RR3

1.0

0.85

(0.71,

1.00)

0.79

(0.66,

0.95)

0.67

(0.56,

0.81)

0.61

(0.49,

0.75)

<0.001

RFS

n

282

247

228

171

211

Age-adjusted RR

1.0

0.85

(0.72,

1.01)

0.75

(0.63,

0.89)

0.64

(0.53,

0.78)

0.69

(0.58,

0.83)

<0.001

Multivariate-adjusted RR3

1.0

0.88

(0.73,

1.02)

0.80

(0.68,

0.94)

0.69

(0.58,

0.83)

0.77

(0.64,

0.93)

<0.001

Cancer5

AHEI

n

328

367

343

321

337

Age-adjusted RR

1.0

1.08

(0.93,

1.25)

0.97

(0.83,

1.13)

0.88

(0.76,

1.03)

0.95

(0.81,

1.10)

0.12

Multivariate-adjusted RR3

1.0

1.10

(0.94,

1.28)

0.99

(0.85,

1.16)

0.94

(0.80,

1.10)

1.03

(0.87,

1.22)

0.66

RFS

n

347

362

334

295

358

Age-adjusted RR

1.0

1.01

(0.87,

1.17)

0.88

(0.76,

1.02)

0.89

(0.76,

1.04)

0.95

(0.82,

1.10)

0.29

Multivariate-adjusted RR3

1.0

1.05

(0.92,

1.20)

0.95

(0.84,

1.09)

0.95

(0.83,

1.10)

1.08

(0.94,

1.25)

0.79

1Test for trend over quintiles of index scores with use of the median value

per quintile.

2Defined as CVD (n = 1092), cancer (n = 1661), or death (n = 366), whichever

came first.

3Adjusted for age (5-y categories), smoking (never, past, 1–14 cigarettes/d,

15–24 cigarettes/d, >25

cigarettes/d), time period, body mass index (quintiles), physical activity (6

categories of metabolic

equivalents), total energy intake (quintiles), and, in all except the cancer

models, history of hypertension or

hypercholesterolemia at baseline. The CVD models include vitamin E and

multivitamin supplement use for

RFS and vitamin E for AHEI.

4Defined as fatal or nonfatal myocardial infarction or stroke or sudden

death.

5Defined as all cancers except nonmalignant skin cancers and nonaggressive

prostate cancers.

TABLE 5 Relative risk (RR) and 95% CIs of major chronic disease, cardiovascular

disease (CVD), and cancer

in women according to Alternate Healthy Eating Index (AHEI) scores and

Recommended Food Scores (RFS)

Quintiles of index scores

1

2

3

4

5

P

for

trend1

Major chronic disease2

AHEI

n

1483

1429

1361

1437

1367

Age-adjusted RR

1.0

0.92

(0.85,

0.99)

0.85

(0.79,

0.92)

0.86

(0.80,

0.92)

0.78

(0.72,

0.84)

<0.001

Multivariate-adjusted RR3

1.0

0.97

(0.90,

1.04)

0.92

(0.85,

0.99)

0.95

(0.88,

1.02)

0.89

(0.82,

0.96)

0.009

RFS

n

1549

1385

1356

1389

1398

Age-adjusted RR

1.0

0.89

(0.83,

0.96)

0.89

(0.83,

0.96)

0.90

(0.84,

0.97)

0.84

(0.78,

0.91)

<0.001

Multivariate-adjusted RR3

1.0

0.95

(0.88,

1.03)

0.98

(0.90,

1.05)

1.02

(0.94,

1.10)

0.98

(0.90,

1.06)

0.89

CVD4

AHEI

n

356

322

267

251

231

Age-adjusted RR

1.0

0.85 (0.73,

0.98)

0.67 (0.58,

0.79)

0.59 (0.50,

0.69)

0.52 (0.44,

0.61)

<0.001

Multivariate-adjusted RR3

1.0

0.95

(0.82,

1.11)

0.80

(0.68,

0.94)

0.75

(0.63,

0.89)

0.72

(0.60,

0.86)

<0.001

RFS

n

343

292

249

281

262

Age-adjusted RR

1.0

0.84

(0.72,

0.98)

0.71

(0.60,

0.84)

0.79

(0.68,

0.93)

0.68

(0.58,

0.80)

<0.001

Multivariate-adjusted RR3

1.0

0.95

(0.81,

1.12)

0.85

(0.72,

1.01)

1.02

(0.86,

1.20)

0.90

(0.75,

1.08)

0.45

Cancer5

AHEI

n

1040

1009

1036

1104

1087

Age, adjusted RR

1.0

0.93

(0.86,

1.02)

0.94

(0.86,

1.02)

0.96

(0.88,

1.05)

0.91

(0.83,

0.99)

0.11

Multivariate-adjusted RR3

1.0

0.95

(0.87,

1.04)

0.97

(0.89,

1.06)

1.00

(0.92,

1.10)

0.97

(0.88,

1.06)

0.92

RFS

n

1102

999

1054

1053

1068

Age-adjusted RR

1.0

0.91

(0.84,

0.99)

0.98

(0.90,

1.07)

0.97

(0.89,

1.06)

0.92

(0.85,

1.01)

0.28

Multivariate-adjusted RR3

1.0

0.94

(0.86,

1.03)

1.03

(0.95,

1.13)

1.04

(0.95,

1.13)

1.00

(0.92,

1.11)

0.39

1Test for trend over quintiles of index scores with use of the median value

per quintile.

2Defined as CVD (n = 1365), cancer (n = 5216), or death (n = 496), whichever

came first.

3Adjusted for age (5-y categories), smoking (never, past, 1–14 cigarettes/d,

15–24 cigarettes/d, >25

cigarettes/d), time period, body mass index (quintiles), physical activity (6

categories of metabolic

equivalents), total energy intake (quintiles), postmenopausal hormone use,

and, in all except the cancer

models, history of hypertension or hypercholesterolemia at baseline. The CVD

models include vitamin E and

multivitamin supplement use for RFS and vitamin E for AHEI.

4Defined as fatal or nonfatal myocardial infarction or stroke or sudden

death.

5Defined as all cancers except nonmalignant skin cancers and in-situ breast

cancers.