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Mambo! Re: carnosine for protein glycosylation

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From pubmed: " Carnosine, which prevents glycation, may also play a

role in the disposal of glycated protein. Carnosinylation tags

glycated proteins for cell removal. "

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?

cmd=Retrieve & db=PubMed & list_uids=12480523 & dopt=Abstract

Wow. I'd never heard of this. I have heard about various " natural "

remedies for neuropathy (usually centering on 'pain') but nothing

nearly this hopeful -- and this is from real biochemical literature!

Do you take carnosine? Have you heard anything about maximum safe

dosages?

> Hello S Rudek,

>

> " aware of work with protein-glycosilation-blocking drugs or

> supplements? 

> Carnosine fits the bill for this. Non toxic even in high doses and

can even

> reverse some of the damage. Aminoguanidine also blocks AGE's at an

earlier

> stage, but there are some questions about its safety.

> Chromium pic supposedly reduces insulin spike as does green tea

before a

> carb meal.

> Metformin reduces sugar/insulin roller coaster and is well

tolerated.

>

> I hope this is helpful. Google and Pubmed have tons of stuff about

carnosine

> and the rest.

> MM

>

>

>

>

>

> _________________________________________________________________

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