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Mambo! Re: carnosine for protein glycosylation

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Have you heard anything about maximum safe dosages?

There seems to be 2 schools of thought regarding Carnosine dosages...

One is that in order to derive carnosine's multiple benefits, it is

critical to consume enough carnosine to saturate the carnosinase

enzyme so as to make free carnosine available to the rest of the body

(500mg).

The thinking behind this is that small dosages of supplemental

carnosine that are often sold by commercial companies provide no

benefit because this small amount of carnosine is degraded by the

carnosinase enzyme before it can produce beneficial effects in the

body.

SOURCE: LEF

On the other hand, others recommend 50-100mg dosages as being

sufficient and their thinking is that some of the benefits of

carnosine are derived AFTER carnosine has been degraded by

carnisinases to produce histidine and alanine. Some of the benefits

may be due to these aminoacids, particularly histidine.

SOURCE: INTERNATIONAL ANTI AGING SYSTEMS

Rob.

> > Hello S Rudek,

> >

> > " aware of work with protein-glycosilation-blocking drugs or

> > supplements? 

> > Carnosine fits the bill for this. Non toxic even in high doses

and

> can even

> > reverse some of the damage. Aminoguanidine also blocks AGE's at

an

> earlier

> > stage, but there are some questions about its safety.

> > Chromium pic supposedly reduces insulin spike as does green tea

> before a

> > carb meal.

> > Metformin reduces sugar/insulin roller coaster and is well

> tolerated.

> >

> > I hope this is helpful. Google and Pubmed have tons of stuff

about

> carnosine

> > and the rest.

> > MM

> >

> >

> >

> >

> >

> > _________________________________________________________________

> > Protect your PC - get McAfee.com VirusScan Online

> > http://clinic.mcafee.com/clinic/ibuy/campaign.asp?cid=3963

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