Re: Hypnosis/sleep & melatonin

[Guest guest]

> From: " Jo " <johastings@s...>

> > I've found melatonin to work extremely well - fall asleep

> > relatively quickly and wake up not feeling groggy or hazy

> > (at least no more than usual!).

> I take Melatonin and a capsule of Valerian Root.

> Together they seem to work very well.

Several people have looked at connections between Melatonin

and CR:

" Roth GS. (2001). Dietary caloric restriction prevents the age-

related decline in plasma melatonin levels of rhesus monkeys.

Journal of Clinical Endocrinology & Metabolism "

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?

cmd=Retrieve & db=PubMed & list_uids=11443203 & dopt=Abstract

" Effect of food restriction on 24-h serum and pineal melatonin

content in male rats. "

" The increased serum M[elatonin] may play a role in the reported

potentiation of pineal action in food deprived rats. "

http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?

uid=3630542 & form=6 & db=m & Dopt=b

" Food restriction retards aging of the pineal gland. "

" It is furthermore proposed that food restriction, which markedly

increases the life span and reduces age-related physiological

deterioration and diseases in many animals, may mediate some of its

effects through a sustained pineal activity in old age. "

http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?

uid=1713529 & form=6 & db=m & Dopt=b

" Undernutrition potentiates melatonin effects in maturing female

rats. "

" These observations emphasize that environmental influences such as

undernutrition can alter the physiological status of immature

animals and enhance the sensitivity of the neuroendocrine axis to

the pineal and one of its hormones, melatonin. "

http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?

uid=2502571 & form=6 & db=m & Dopt=b

These effects - in conjunction with a reduced frequency of bowl

disturbances through digestion during the night - suggest to me

that vanilla CR might itself help with restless sleep.