Guest guest Posted March 2, 2003 Report Share Posted March 2, 2003 Hi Alan, We had a big discussion on the PCa group, and the problem with rooibos is a disagreement using the " green " (immature Aspalathus linearis), versus oxidized as in processed (also sterilized). Then there's the " green tea " (Camellia sinensis) for which an extract is available. Comparing the two, at present, I have to choose the green tea caps. Rooibos may be 50 times more effective, but not for the green tea cap, IMO. Need rooibos caps and tests. I was concerned about several aspects of the rooibos, not the least is the req't to boil green rooibos for 20 mine to remove all the anti-oxies. That's also needed to kill the microorgs which I think is the real reason to boil it that long. Too many unknowns. There is also some question where the rooibos comes from. Although they advertise Africa, there is also an Indian variety. Not the standardization yet of the green tea. It reportedly has no caffeinne. Regards. ----- Original Message ----- From: Alan Pater 'CR List' Cc: CR Support Group (E-mail) Sent: Sunday, March 02, 2003 6:28 AM Subject: [ ] Rooibos herbal tea for what may ail you Hi All, Only one previous post describe Rooibos herbal tea for benefits: Item #16979 (1 Mar 2001 21:50) - [CR] Re: Green Tea & Fluoride 2000; Alternative Medicine, Nov 2000) about recent (but unamed, alas) studies showing one herbal tea, *rooibos*, has antioxidant properties up to 50 times more potent than green tea. It contains iron, potassium, calcium,... I seems to be that the herbal rooibos tea does great things in the update below. Cheers, Al. 1: Edenharder R, Sager JW, Glatt H, Muckel E, Platt KL. Protection by beverages, fruits, vegetables, herbs, and flavonoids against genotoxicity of 2-acetylaminofluorene and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in metabolically competent V79 cells. Mutat Res. 2002 Nov 26;521(1-2):57-72. Chinese hamster lung fibroblasts, genetically engineered for the expression of rat cytochrome P450 dependent monooxygenase 1A2 and rat sulfotransferase 1C1 (V79-rCYP1A2-rSULT1C1 cells), were utilized to check for possible protective effects of beverages of plant origin, fruits, vegetables, and spices against genotoxicity induced by 2-acetylaminofluorene (AAF) or 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). Antigenotoxic activities of juices from spinach and red beets against AAF could be monitored with similar effectivity by the HPRT-mutagenicity test (IC(50)=0.64%; 2.57%) and alkaline single cell gel electrophoresis (comet assay; IC(50)=0.12%; 0.89%) which detects DNA strand breaks and abasic sites. Applying the comet assay, genotoxicity of PhIP could, however, be demonstrated only in the presence of hydroxyurea and 1-[beta-D-arabinofuranosyl]cytosine, known inhibitors of DNA repair synthesis. As expected, AAF and PhIP were unable to induce any genotoxic effects in the parent V79 cells. Genotoxic activity of PhIP was strongly reduced in a dose-related manner by green tea and red wine, by blueberries, blackberries, red grapes, kiwi, watermelon, parsley, and spinach, while two brands of beer, coffee, black tea, rooibos tea, morellos, black-currants, plums, red beets, broccoli (raw and cooked), and chives were somewhat less active. One brand of beer was only moderately active while white wine, bananas, white grapes, and strawberries were inactive. Similarly, genotoxicity of AAF was strongly reduced by green, black, and rooibos tea, red wine, morellos, black-currants, kiwi, watermelon, and spinach while plums, red beets, and broccoli (raw) were less potent. Broccoli cooked exerted only moderate and white wine weak antigenotoxic activity. With respect to the possible mechanism(s) of inhibition of genotoxicity, benzo[a]pyrene-7,8-dihydrodiol (BaP-7,8-OH) and N-OH-PhIP were applied as substrates for the CYP1A family and for rSULT 1C1, respectively. Morellos, black-currants, and black tea strongly reduced the genotoxicity of BaP-7,8-OH, onions, rooibos tea, and red wine were less potent while red beets and spinach were inactive. On the other hand, red beets and spinach strongly inhibited the genotoxicity of N-OH-PhIP, rooibos tea was weakly active while all other items were inactive. These results are suggestive for enzyme inhibition as mechanism of protection by complex mixtures of plant origin. Taken together, our results demonstrate that protection by beverages, fruits, and vegetables against genotoxicity of heterocyclic aromatic amines may take place within metabolically competent mammalian cells as well as under the conditions of the Salmonella/reversion assay. PMID: 12438004 [PubMed - indexed for MEDLINE] 3: Kunishiro K, Tai A, Yamamoto I. Effects of rooibos tea extract on antigen-specific antibody production and cytokine generation in vitro and in vivo. Biosci Biotechnol Biochem. 2001 Oct;65(10):2137-45. PMID: 11758901 [PubMed - indexed for MEDLINE] 6: Standley L, Winterton P, Marnewick JL, Gelderblom WC, Joubert E, Britz TJ. Influence of processing stages on antimutagenic and antioxidant potentials of rooibos tea. J Agric Food Chem. 2001 Jan;49(1):114-7. PMID: 11170567 [PubMed - indexed for MEDLINE] 7: Marnewick JL, Gelderblom WC, Joubert E. An investigation on the antimutagenic properties of South African herbal teas. Mutat Res. 2000 Nov 20;471(1-2):157-66. PMID: 11080671 [PubMed - indexed for MEDLINE] 11: Nakano M, Itoh Y, Mizuno T, Nakashima H. Polysaccharide from Aspalathus linearis with strong anti-HIV activity. Biosci Biotechnol Biochem. 1997 Feb;61(2):267-71. PMID: 9058964 [PubMed - indexed for MEDLINE] 14: Inanami O, Asanuma T, Inukai N, Jin T, Shimokawa S, Kasai N, Nakano M, Sato F, Kuwabara M. The suppression of age-related accumulation of lipid peroxides in rat brain by administration of Rooibos tea (Aspalathus linearis). Neurosci Lett. 1995 Aug 18;196(1-2):85-8. PMID: 7501264 [PubMed - indexed for MEDLINE] 16: Sasaki YF, Yamada H, Shimoi K, Kator K, Kinae N. The clastogen-suppressing effects of green tea, Po-lei tea and Rooibos tea in CHO cells and mice. Mutat Res. 1993 Apr;286(2):221-32. PMID: 7681534 [PubMed - indexed for MEDLINE] 19: Hesseling PB, Joubert JR. The effect of rooibos tea on the type I allergic reaction. S Afr Med J. 1982 Dec 25;62(27):1037-8. No abstract available. PMID: 7179042 [PubMed - indexed for MEDLINE] 20: Hesseling PB, Klopper JF, van Heerden PD. [The effect of rooibos tea on iron absorption] S Afr Med J. 1979 Apr 14;55(16):631-2. Afrikaans. A study was carried out to determine if rooibos tea (Aspalathus linearis) has a deleterious effect on iron absorption similar to that of ordinary tea (Camellia sinensis). Three groups of volunteers, each consisting of 10 healthy young men comparable with regard to iron status and body dimensions, were studied. After ingestion of 1 muCi 59Fe and 16 mg of elemental iron, group A drank rooibos tea, group B ordinary tea and group C boiled water. Iron absorption was measured 14 days later with a whole body counter. Mean iron absorption after ingestion of rooibos tea, ordinary tea, and water was 7,25%, 1,70% and 9,34% respectively. In contrast to ordinary tea (P less than 0,0001), rooibos tea did not affect iron absorption significantly. The ascorbic acid content of rooibos tea varies between 121,8 and 154,9 mumol/l, depending on the method of preparation. Rooibos tea contains small amounts of iron, magnesium, phosphorus, sodium, chloride and potassium. These findings have practical nutritional and therapeutic implications. PMID: 462276 [PubMed - indexed for MEDLINE] Quote Link to comment Share on other sites More sharing options...
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