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Hi All, I was surprised by this. I have excess stroke risk from family

history.

Cheers, Al.

J Nutr Sci Vitaminol (Tokyo) 1997 Feb;43(1):83-99

Dietary lipids and incidence of cerebral infarction in a Japanese rural

community.

Seino F, Date C, Nakayama T, Yoshiike N, Yokoyama T, Yamaguchi M, Tanaka H.

OBJECTIVE: To assess the relationship between dietary lipids and incidence

of cerebral infarction in a Japanese rural population.

DESIGN: A cohort study from July 1977 through December 1992.

SETTING: Akadani-Ijimino (A-I) district, Niigata Prefecture, Japan.

Subjects and METHODS: All the residents, 1,182 men and 1,469 women, aged 40

years and over. Out of these members, 954 men and 1,329 women who were

initially free of stroke completed a semiquantitative food frequency

questionnaire in 1977, and were then subjected to a follow-up for 15.5

years. The occurrence of stroke was determined by the annual follow-up

examination and registry. Dietary lipid was adjusted for total energy or fat

intake by the residual method. Sex- and age-stratified and blood pressure-

and atrial fibrillation-adjusted relative risk for cerebral infarction was

estimated by the proportional hazard model.

RESULTS: There were 75 new cases of cerebral infarction during the

observation period. The relative risk for cerebral infarction was less than

one in the highest quartile level of total fat, saturated fatty acids (S),

Keys score and westernized dietary pattern: 0.68-0.94. It ranged between

1.36 and 1.57 in the highest level of polyunsaturated (P), n-3 and n-6 fatty

acids, and P/S ratio.

CONCLUSION: This study suggests the possibility that the traditional

Japanese diet, very low fat intake, was likely to increase the risk of

stroke through the low level of serum cholesterol as an intermediary factor.

PMID: 9151243 [PubMed - indexed for MEDLINE]

Alan Pater, Ph.D.; Faculty of Medicine; Memorial University; St. 's, NL

A1B 3V6 Canada; Tel. No.: (709) 777-6488; Fax No.: (709) 777-7010; email:

apater@...

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