Re: [CR] Lane Paper on CR in Primates

[Guest guest]

Hi All, I thought you might like the below. I guess it more or less

explains where CR stands in even those we would think care about it.

Cheers, Al.

On Tue, 19 Nov 2002 14:06:57 -0800, zod <scalzod@...> wrote:

> I heard Lane present this data at symposium honoring 's

>upcoming retirement. Slide after slide of the data showing the benefits of

>CR (and the converse for the controls) in primates.

> His session was just prior to a break. As soon as he finished,

everyone

>dove for the Donuts, Pastries and Coffee.

> Damn funny.

>

>

Hi Dave and all,

I can understand this as funny as it sounds. I remember how I had for

several years been reading anti-aging research and kept coming across cr

studies, and the most powerful thing about it was that no one was selling

it or making money on it which made it all the more creditable. However,

even with this knowledge I merely accepted the conventional wisdom that it

was undoable. It wasn't until I read Walford's original book on the subject

that I considered doing it myself. Which is I think a testement to his

greatness. He was willing to break out of the conventional wisdom and

forge new ground, although Biosphere helped.

I think most of those people at the conference you write about are the same

in that as much as any rationale person would want the benefits of cr, as

long as they were willing to put up with the few downsides, they are

conventional and herdlike in their mentality to the point that they beleive

it is undoable or very painful when in fact for many it isn't. In fact

some on the list, including myself would say it greatly improves life

quality.

The more of us who succeed at cr there are the more that herdlike mentality

will be broken down. but it will take time because of so many

misconceptions and confusions.

Regards,

Mike Colella

>On 11/18/02 6:21 PM, " Dean Pomerleau " <deanp@...> wrote:

>

><SNIP>

>>

>> But probably justifiably, they aren't optimistic about the potential for

>> many people to follow a CR diet. Instead they focus on the search for a

>> CR-mimic, an intervention that will provide the health/lifespan benefits

>> of CR without reducing in food:

>>

>> " Even if CR is eventually shown to retard human

>> aging and to enhance the quality of life in later years,

>> it is not likely that the strict dietary control needed

>> would become a widespread practice. The popularity of

>> fad diets, weight loss pills and programs in addition to

>> the well-known difficulties in maintaining weight loss,

>> argue against the likelihood of a large-scale application

>> of a CR regimen among people. Thus, we have chosen

>> to investigate the possible development of " CR mimetics "

>> as an alternative to the strict diet regimen of CR. A

>> CR mimetic can be loosely defined as any intervention

>> that produces selected beneficial effects of CR on aging without causing

>> or requiring a significant reduction in caloric intake. "

>>

>> --Dean

>>

>> ------------------------------------------------------------

>> [1] Microsc. Res. Tech. 59: 335-338, 2002.

>>

>> Caloric Restriction and Aging in Primates: Relevance to

>> Humans and Possible CR Mimetics

>>

>> MARK A. LANE,* JULIE MATTISON, DONALD K. INGRAM, AND GEORGE S. ROTH

>> PMID: 12424798

>

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Alan Pater, Ph.D.; Faculty of Medicine; Memorial University; St. 's, NL

A1B 3V6 Canada; Tel. No.: (709) 777-6488; Fax No.: (709) 777-7010; email:

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