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Info sought on later life onset of CR

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From what I have read in the medical literature, it is unclear to

what it the maximum age at which a person may begin caloric

restriction and still have a reasonable expectation of an increased

maximum lifespan.

Can anyone direct me to some good resources on this, including

perhaps a section of these messages that may have dealt with this

very question?

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Hi Physics,

I'm not sure if the topic has been covered on this list, but the other more

science-oriented CR listserv did discuss this extensively four or five years

ago.

Walford talks about it a bit in his _Beyond the 120 Year Diet_, and I think

the lab evidence with rodents pointed to benefits even late in life, but

shortly after puberty (or before maturity) had the greatest life-extension

benefits. However, this came at the cost of higher mortality in very early

life and reduced body size. As a result, Walford recommends CR only after

having become fully grown, and the extension of maximum lifespan in rodents

even well after reaching maturity are still quite remarkable.

As a worst case scenario, CR late in life will at least offer benefits with

preventing diabetes, cancer, heart disease, and stroke... Even if it

doesn't extend " maximum lifespan, " it could very well increase the length of

time one's around under that normal cap of 110 or so...

Cheers,

> -----Original Message-----

> From: physics_4_ever [mailto:theoretical_physics@...]

> Sent: Monday, July 14, 2003 8:25 PM

>

> Subject: [ ] Info sought on later life onset of CR

>

>

> >From what I have read in the medical literature, it is unclear to

> what it the maximum age at which a person may begin caloric

> restriction and still have a reasonable expectation of an increased

> maximum lifespan.

>

> Can anyone direct me to some good resources on this, including

> perhaps a section of these messages that may have dealt with this

> very question?

>

>

>

>

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Hi All,

From the main list new web site at:

http://www045.heronetwork.com/

you can go to General information at:

http://www045.heronetwork.com/modules.php?

name=Sections & op=listarticles & secid=3

and then Compelling Graphs of CR Benefits at:

http://www045.heronetwork.com/modules.php?

name=Sections & op=viewarticle & artid=12

which shows that " A postive linear relationship is observed between

the duration of CR feeding and the maximum lifespan recorded in

rodent species. "

Cheers, Al.

--- In , " Gifford " <gifford@u...>

wrote:

> Hi Physics,

>

> I'm not sure if the topic has been covered on this list, but the

other more

> science-oriented CR listserv did discuss this extensively four or

five years

> ago.

>

> Walford talks about it a bit in his _Beyond the 120 Year Diet_, and

I think

> the lab evidence with rodents pointed to benefits even late in

life, but

> shortly after puberty (or before maturity) had the greatest life-

extension

> benefits. However, this came at the cost of higher mortality in

very early

> life and reduced body size. As a result, Walford recommends CR

only after

> having become fully grown, and the extension of maximum lifespan in

rodents

> even well after reaching maturity are still quite remarkable.

>

> As a worst case scenario, CR late in life will at least offer

benefits with

> preventing diabetes, cancer, heart disease, and stroke... Even if

it

> doesn't extend " maximum lifespan, " it could very well increase the

length of

> time one's around under that normal cap of 110 or so...

>

> Cheers,

>

>

> > -----Original Message-----

> > From: physics_4_ever [mailto:theoretical_physics@l...]

> > Sent: Monday, July 14, 2003 8:25 PM

> >

> > Subject: [ ] Info sought on later life onset of CR

> >

> >

> > >From what I have read in the medical literature, it is unclear to

> > what it the maximum age at which a person may begin caloric

> > restriction and still have a reasonable expectation of an

increased

> > maximum lifespan.

> >

> > Can anyone direct me to some good resources on this, including

> > perhaps a section of these messages that may have dealt with this

> > very question?

> >

> >

> >

> >

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  • 3 weeks later...
Guest guest

Thanks for the responses to my questions....

I have been out of state recently, or I would have responded sooner.

I am now absorbing as much practical information as I need to ease

into a CR diet. I appreciate the existence of this group.

> > Hi Physics,

> >

> > I'm not sure if the topic has been covered on this list, but the

> other more

> > science-oriented CR listserv did discuss this extensively four or

> five years

> > ago.

> >

> > Walford talks about it a bit in his _Beyond the 120 Year Diet_,

and

> I think

> > the lab evidence with rodents pointed to benefits even late in

> life, but

> > shortly after puberty (or before maturity) had the greatest life-

> extension

> > benefits. However, this came at the cost of higher mortality in

> very early

> > life and reduced body size. As a result, Walford recommends CR

> only after

> > having become fully grown, and the extension of maximum lifespan

in

> rodents

> > even well after reaching maturity are still quite remarkable.

> >

> > As a worst case scenario, CR late in life will at least offer

> benefits with

> > preventing diabetes, cancer, heart disease, and stroke... Even

if

> it

> > doesn't extend " maximum lifespan, " it could very well increase

the

> length of

> > time one's around under that normal cap of 110 or so...

> >

> > Cheers,

> >

> >

> > > -----Original Message-----

> > > From: physics_4_ever [mailto:theoretical_physics@l...]

> > > Sent: Monday, July 14, 2003 8:25 PM

> > >

> > > Subject: [ ] Info sought on later life onset of CR

> > >

> > >

> > > >From what I have read in the medical literature, it is unclear

to

> > > what it the maximum age at which a person may begin caloric

> > > restriction and still have a reasonable expectation of an

> increased

> > > maximum lifespan.

> > >

> > > Can anyone direct me to some good resources on this, including

> > > perhaps a section of these messages that may have dealt with

this

> > > very question?

> > >

> > >

> > >

> > >

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