leaky gut impoved with FOS

[Guest guest]

Good news for leaky gut sufferers that the inulin/FOS they use

heals leaky gut by supporting bowel lining epithelial cell growth

as well as that of probiotic Bifidobacteria.

I haven't got this one up on my website yet, I'll put it in the

inulin references http://tinyurl.com/3nxva

Two experiments were conducted to determine if supplementing

soluble fiber (fructooligosaccharide, xylooligosaccharide or gum

arabic) to a semi-elemental diet would beneficially change cecal

and colonic microbiota populations and enhance epithelial cell

proliferation. Experiments 1 and 2 used identical dietary

regimens; mice and rats were given free access to a powdered semi-

elemental diet. Animals were assigned to one of the four

following treatment groups: control, no supplemental dietary

fiber, fructooligosaccharide, xylooligosaccharide and gum arabic.

Dietary fiber was supplied via drinking water at 30 g/L. In

Experiment 1 populations of Bifidobacteria and total anaerobic

flora were enumerated from the contents of the cecum and colon of

weanling mice. Consumption of fructooligosaccharide increased (P

< 0.05) the concentrations of Bifidobacteria and the ratio of

Bifidobacteria to total anaerobic flora. In Experiment 2 tissue

from the cecum and distal colon of weanling rats was examined for

morphological changes of the mucosa. Consumption of

xylooligosaccharide increased (P < 0.05) cecal crypt depth and

labeling index relative to the other three treatments.

Consumption of gum arabic and the control diet increased (P <

0.01) cecal proliferation zone. Consumption of

xylooligosaccharide and the control diet increased (P < 0.01)

cecal cell density (number of cells in a vertical-half of the

crypt). Distal colonic crypt depth was greatest (P < 0.05) in

controls and rats fed fructooligosaccharide, intermediate in

those fed gum arabic, and smallest in those fed

xylooligosaccharide.

[Guest guest]

Great! I just started taking inulin yesterday per your advice, Duncan. Right now

I am only taking 1 serving per day. Is that adequate?

Thanks,

Olif

[Guest guest]

Duncan,

What if you can't take FOS because of having Klebsiella in the past? Tested

positive in 1998, not in 2000. Have read that FOS can encourage the growth of

Klebsiella. Last week, I had to change my probiotic w/FOS to one with Inulin.

Beth

leaky gut impoved with FOS

Good news for leaky gut sufferers that the inulin/FOS they use

heals leaky gut by supporting bowel lining epithelial cell growth

as well as that of probiotic Bifidobacteria.

I haven't got this one up on my website yet, I'll put it in the

inulin references http://tinyurl.com/3nxva

Two experiments were conducted to determine if supplementing

soluble fiber (fructooligosaccharide, xylooligosaccharide or gum

arabic) to a semi-elemental diet would beneficially change cecal

and colonic microbiota populations and enhance epithelial cell

proliferation. Experiments 1 and 2 used identical dietary

regimens; mice and rats were given free access to a powdered semi-

elemental diet. Animals were assigned to one of the four

following treatment groups: control, no supplemental dietary

fiber, fructooligosaccharide, xylooligosaccharide and gum arabic.

Dietary fiber was supplied via drinking water at 30 g/L. In

Experiment 1 populations of Bifidobacteria and total anaerobic

flora were enumerated from the contents of the cecum and colon of

weanling mice. Consumption of fructooligosaccharide increased (P

< 0.05) the concentrations of Bifidobacteria and the ratio of

Bifidobacteria to total anaerobic flora. In Experiment 2 tissue

from the cecum and distal colon of weanling rats was examined for

morphological changes of the mucosa. Consumption of

xylooligosaccharide increased (P < 0.05) cecal crypt depth and

labeling index relative to the other three treatments.

Consumption of gum arabic and the control diet increased (P <

0.01) cecal proliferation zone. Consumption of

xylooligosaccharide and the control diet increased (P < 0.01)

cecal cell density (number of cells in a vertical-half of the

crypt). Distal colonic crypt depth was greatest (P < 0.05) in

controls and rats fed fructooligosaccharide, intermediate in

those fed gum arabic, and smallest in those fed

xylooligosaccharide.

[Guest guest]

Olif,

As my inulin pages note, a daily dose of 12-15 grams is about

three teaspoons. Much less gas is apparent when people divide the

daily amount into three or four and take it with food, more like

you'd get it naturally if it was in the food, but certainly you

can take it all at once.

Incidentally although leaky gut improves with FOS it also

improves with longer-chained inulin, and inulin does not produce

FOS-related setbacks.

Duncan

On 21 Jun 2006 at 6:02, candidiasis wrote:

>

> Posted by: " Olif " OVanPelt@... olifmary

> Date: Tue Jun 20, 2006 3:50 pm (PDT)

>

> Great! I just started taking inulin yesterday per your advice, Duncan.

> Right now I am only taking 1 serving per day. Is that adequate?

>

> Thanks,

> Olif

[Guest guest]

Duncan,

What if you can't take FOS because of having Klebsiella in the past? Tested

positive in 1998, not in 2000. Have read that FOS can encourage the growth of

Klebsiella. Last week, I had to change my probiotic w/FOS to one with Inulin.

Beth

leaky gut impoved with FOS

Good news for leaky gut sufferers that the inulin/FOS they use

heals leaky gut by supporting bowel lining epithelial cell growth

as well as that of probiotic Bifidobacteria.

I haven't got this one up on my website yet, I'll put it in the

inulin references http://tinyurl.com/3nxva

Two experiments were conducted to determine if supplementing

soluble fiber (fructooligosaccharide, xylooligosaccharide or gum

arabic) to a semi-elemental diet would beneficially change cecal

and colonic microbiota populations and enhance epithelial cell

proliferation. Experiments 1 and 2 used identical dietary

regimens; mice and rats were given free access to a powdered semi-

elemental diet. Animals were assigned to one of the four

following treatment groups: control, no supplemental dietary

fiber, fructooligosaccharide, xylooligosaccharide and gum arabic.

Dietary fiber was supplied via drinking water at 30 g/L. In

Experiment 1 populations of Bifidobacteria and total anaerobic

flora were enumerated from the contents of the cecum and colon of

weanling mice. Consumption of fructooligosaccharide increased (P

< 0.05) the concentrations of Bifidobacteria and the ratio of

Bifidobacteria to total anaerobic flora. In Experiment 2 tissue

from the cecum and distal colon of weanling rats was examined for

morphological changes of the mucosa. Consumption of

xylooligosaccharide increased (P < 0.05) cecal crypt depth and

labeling index relative to the other three treatments.

Consumption of gum arabic and the control diet increased (P <

0.01) cecal proliferation zone. Consumption of

xylooligosaccharide and the control diet increased (P < 0.01)

cecal cell density (number of cells in a vertical-half of the

crypt). Distal colonic crypt depth was greatest (P < 0.05) in

controls and rats fed fructooligosaccharide, intermediate in

those fed gum arabic, and smallest in those fed

xylooligosaccharide.

[Guest guest]

Duncan,

What if you can't take FOS because of having Klebsiella in the past? Tested

positive in 1998, not in 2000. Have read that FOS can encourage the growth of

Klebsiella. Last week, I had to change my probiotic w/FOS to one with Inulin.

Beth

leaky gut impoved with FOS

Good news for leaky gut sufferers that the inulin/FOS they use

heals leaky gut by supporting bowel lining epithelial cell growth

as well as that of probiotic Bifidobacteria.

I haven't got this one up on my website yet, I'll put it in the

inulin references http://tinyurl.com/3nxva

Two experiments were conducted to determine if supplementing

soluble fiber (fructooligosaccharide, xylooligosaccharide or gum

arabic) to a semi-elemental diet would beneficially change cecal

and colonic microbiota populations and enhance epithelial cell

proliferation. Experiments 1 and 2 used identical dietary

regimens; mice and rats were given free access to a powdered semi-

elemental diet. Animals were assigned to one of the four

following treatment groups: control, no supplemental dietary

fiber, fructooligosaccharide, xylooligosaccharide and gum arabic.

Dietary fiber was supplied via drinking water at 30 g/L. In

Experiment 1 populations of Bifidobacteria and total anaerobic

flora were enumerated from the contents of the cecum and colon of

weanling mice. Consumption of fructooligosaccharide increased (P

< 0.05) the concentrations of Bifidobacteria and the ratio of

Bifidobacteria to total anaerobic flora. In Experiment 2 tissue

from the cecum and distal colon of weanling rats was examined for

morphological changes of the mucosa. Consumption of

xylooligosaccharide increased (P < 0.05) cecal crypt depth and

labeling index relative to the other three treatments.

Consumption of gum arabic and the control diet increased (P <

0.01) cecal proliferation zone. Consumption of

xylooligosaccharide and the control diet increased (P < 0.01)

cecal cell density (number of cells in a vertical-half of the

crypt). Distal colonic crypt depth was greatest (P < 0.05) in

controls and rats fed fructooligosaccharide, intermediate in

those fed gum arabic, and smallest in those fed

xylooligosaccharide.

[Guest guest]

Most commonly people would report back that in just ten days (or

a month) their bowel has felt better than it had in more than 10

years with Crohn's disease, things like that.

When you look closely at the negative comments about prebiotics

you find they were mostly uninformed and speculative and

originated from a group that espouses an anti-fermentation stance

that remains completely unsupported by evidence. There were a few

people who had prior serious issues they felt were exacerbated in

the first couple of days, would not persist and did not benefit

in the long term. These are inconclusive either way; I pointed

out the research specifies beneficial changes occur in two to

four weeks, and we've noted improvement for another four weeks.

A red herring question sometimes raised is whether inulin, a

spray dried water extract, qualifies as a " chemical supplement " ,

by inference to be avoided. Although some people may well eat the

tea bags rather than brewing and drinking their tea, it doesn't

make either one a chemical supplement.

A pertinent and practical question that makes more sense: What

justifies using the supplement? The answer - to address a dietary

deficiency. What has been established by research is that we

historically got 20-30 grams of inulin daily in Europe for

example, research shows the optimal is about 15 grams, and also

that most of us are deficient by 12 grams, which is why we

suffer. This answers the related question: Why did we get IBS,

Crohn's, colitis and candida in the first place?

We've been using inulin broth for more than 5,000 years for the

exactly same problems, and we only forgot about it in recent

memory. So today, we make sure we get the 15 grams or suffer the

consequences.

> After starting the inulin yesterday, I have bloating today and loose

> stools. :-( I haven't had any bloating for the past 2 weeks that I

> have been on my anti-Candida diet. I think it must be the inulin. I

> will discontinue it for now...

>

> Thanks,

> Olif

>

Olif, you're addressing a complex ecology. The gas will resolve

as the bacterial count in the bowel contents changes (not the

bowel lining, that takes longer) to approach normal in a few to

several days, and gas reduces a bit when you reduce the dose and

take it more often. What you're looking for is extensive contact

time between the gut bacteria and their feed. Amounts larger than

what the probiotic bacteria can ferment during that time are

simply an insoluble fiber.

Duncan

Duncan

[Guest guest]

Beth, I think a couple of test tube studies put FOS in pure

cultures of klebsiella or others and got them to grow. In the

real world there is concomittal probiotic fluorish that does not

allow the pathogens to survive.

Anyway, I don't recommend FOS but inulin; klebsiella doesn't

ferment inulin. Native inulin is only 2% or so FOS and 6% - 11%

sugar; there won't be a problem with this tiny amount.

Duncan

> Re: leaky gut impoved with FOS

> Posted by: " Beth Fish " bethafish@... bethafish1

> Date: Thu Jun 22, 2006 11:01 am (PDT)

>

> Duncan,

>

> What if you can't take FOS because of having Klebsiella in the past?

> Tested positive in 1998, not in 2000. Have read that FOS can

> encourage the growth of Klebsiella. Last week, I had to change my

> probiotic w/FOS to one with Inulin.

>

> Beth