Alan Pater: Post Glucose Crisis Blood Tests

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Hi All, Here for your information is a run-down of my blood test results

since my glucose crisis on March 13, 2003. The results may be informative

regarding how CR might protect CRers from a severe stress event. My best

guess is that I weighed about 88-90 pounds at the time, having come down

from an ad lib 157 or so. I had a case of pretty severe pneumonia.

Overall, there seemed to me to be a shock wave of abnormalities, most of

which rapidly improved to the pre-crisis levels. Measures that showed no

significant deviation from previous levels are not mentioned below.

My glucose versus 3.5-5 reference range values were:

for the 13th at 626 (that is 6:26 am), 2.5; 1.1 at 1400 (2 pm);

Ø 6.1 until glucose intravenous stopped at 2000 on the 14th;

Ø 3.8 on the 15th at 300 so I ate; 6.3 at 345; 6.6 at 614;

Ø 3.2 at 748; 5.1 after oatmeal at 840;

Ø 4.6 at 1100; okay the rest of the 15th;

Ø on the 16th 5.1 at 310 and take oatmeal;

Ø 4.9 at 600;

Ø on the 17th 4.5 at 635 and ate a little before fasting until 1100 for CAT

scan after which it was 2.2;

Ø 3.5 at 1100; 3.8 at 1245;

Ø 6.0 at 1322; 3.8 at 1457;

Ø 5.0 at 1550; the 18th at 640 3.7;

Ø the next lows were at about 700 each day and about 4.0 with 3.5 on the

26th.

Of note, before my crisis my levels had remained above 4.0 after fasting as

much as 16 hours on the latest glucose tolerance test on Nov, 7, 2003 when

it was 4.4.

Creatinine was a little low from the 18th March until the 28th.

White blood cells (wbc) were relative to reference range 4.8-10.8 and my

usual average of 2.2 over the last 2 years:

3.8 on Mar. 13 at 626 indicating they were elevated to fight the pneumonia;

3.0 on the 18th;

2.4 on the 19th;

2.0 on the 26th;

3.3 on the 28th;

1.8 on the 31st;

1.4 on the 2nd of April;

and later values of 2.2, 1.4 and 1.6.

My neutrophils that they were more concerned about were versus reference

range 2.0-7.5 and my average of 1.4:

3.3 on the 13th at 626 again indicating infection fighting;

2.5 on the 18th;

1.9 on the 19th;

1.2 on the 26th;

0.8 on the 31st;

1.4 on the 4th of April;

0.7 on the 7th;

and 0.9 on the 11th.

So, it seems to me that they were high for the infection and returned to low

level when antibiotic was given and when the infection passed.

Monocytes showed somewhat similar but higher levels.

Lymphocytes were versus reference rang 1.5-4.0 and my usual about 0.5 over

the last 3 years:

0.2 on Mar.

1.3 at 626;

0.3 on the 18th and 19th;

0.5 on the 26th;

1.1 on the 28th;

0.7 on the 31st;

0.5 on April 2nd;

and more of similar values thereafter.

My platelets were versus the reference range of 130-400 and normal slightly

above or below the low in the reference range:

139 on the 13th at 626;

109 on the 18th;

103 on the 19th;

and return to ~a third above the low in the reference range thereafter.

For liver damage markers were:

PT versus reference range of 10.4-13.0 seconds:

19.6 on the 13th at 1519;

13.0 on the 17th;

and 2.6 on April 4th.

The INR versus reference range 0.80-1.20:

2.22 on the 13th;

1.21 on the 17th;

and 1.15 on April 4th.

The aspartate aminotransferase (AST) versus my traditional ? and reference

range 0-37 values were:

64 at 1519 on the 13th of March;

335 later on the 13th; and

32-44 after the 30th.

The alanine aminotransferase (ALT) values versus my traditional ? and 0-37

reference range were:

33 at 1519 on the 13th;

132 later on the 13th;

and ~28 on and after the 28th.

Not really for liver damage, but bilirubin went from lately normal levels to

versus reference range 0-20:

35 on March 13 at 1519;

25 on the 18th;

and thereafter similar levels.

For heart damage marker, troponin I at 0 hours versus reference range 0-0.05

values were:

0.11 for 0 hours 13th of March at 1519;

0.29 at 1905 for 3 hours; and

0.01 on April 1st for 0 hours.

This diet in the hospital is okay for vegetables but not for fats or

alcohol, for which I am fussy. My lipid values reflect the same: values on

April 7, 2003 versus Nov. 7, 2002 were: cholesterol, 2.29 versus 2.15;

triglycerides 0.47 versus 0.36; HDL 0.69 versus 1.01; LDL 1.39 versus 1.01;

and cholesterol/HDL ratio 3.3 versus 2.1.

Cheers, Al.

Alan Pater, Ph.D.; Faculty of Medicine; Memorial University; St. 's, NL

A1B 3V6 Canada; Tel. No.: (709) 777-6488; Fax No.: (709) 777-7010; email:

apater@...