More reason not to take estrogen and progestin

[Guest guest]

Hi All,

The below and the previous paper by the same people suggest strongly not to

take estrogen and progestin.

The PDF for both is available.

Cheers, Al.

JAMA. 2003;289:2651-2662.

Conclusions Estrogen plus progestin therapy increased the risk for probable

dementia in postmenopausal women aged 65 years or older. In addition,

estrogen plus progestin therapy did not prevent mild cognitive impairment in

these women. These findings, coupled with previously reported WHI data,

support the conclusion that the risks of estrogen plus progestin outweigh

the benefits.

CONCLUSIONS: In this trial in postmenopausal women, estrogen plus progestin

did not have a clinically meaningful effect on health-related quality of

life.

PMID: 12642637 [PubMed - indexed for MEDLINE]

Alan Pater, Ph.D.; Faculty of Medicine; Memorial University; St. 's, NL

A1B 3V6 Canada; Tel. No.: (709) 777-6488; Fax No.: (709) 777-7010; email:

apater@...

[Guest guest]

And it wasn't very long ago that they were saying that HRT PREVENTED memory

loss!!

on 5/27/2003 5:23 PM, Alan Pater at apater@... wrote:

> Conclusions Estrogen plus progestin therapy increased the risk for probable

> dementia in postmenopausal women aged 65 years or older. In addition,

> estrogen plus progestin therapy did not prevent mild cognitive impairment in

> these women. These findings, coupled with previously reported WHI data,

> support the conclusion that the risks of estrogen plus progestin outweigh

> the benefits.