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I've been taking melatonin nightly for years for it's antioxidant and

possible other health and longevity benefits, but, although I regularly take

6 grams/night, I really never noticed any detectable clinical effect I could

discern.

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>From: Francesca Skelton <fskelton@...>

>Reply-

>support group < >

>Subject: [ ] melatonin

>Date: Mon, 15 Sep 2003 13:30:19 -0400

>

>As the veterans in the group know, I've often complained about poor sleep.

>In the past I had tried melatonin and never noticed a difference in sleep.

>A few days ago I again tried melatonin and am sleeping somewhat better, not

>perfect, but better. It's possible I didn't take a high enough dose in the

>past and even now perhaps I should take a bit more (I'm taking about 2

>mgms).

>

>However I have noticed a tremendous increase in energy. I wake up in the

>am

>raring to go (which is itself unusual as I've always been a slow riser) and

>accomplish much more than I used to. Is anyone else taking melatonin? If

>so, any beneficial side effects such as what I think I'm getting from it?

>

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Is melatonin expensive? Is it useful for those who already have

perfect or near perfect sleep?

-

> As the veterans in the group know, I've often complained about poor

sleep.

> In the past I had tried melatonin and never noticed a difference in

sleep.

> A few days ago I again tried melatonin and am sleeping somewhat

better, not

> perfect, but better. It's possible I didn't take a high enough dose

in the

> past and even now perhaps I should take a bit more (I'm taking about 2

> mgms).

>

> However I have noticed a tremendous increase in energy. I wake up

in the am

> raring to go (which is itself unusual as I've always been a slow

riser) and

> accomplish much more than I used to. Is anyone else taking

melatonin? If

> so, any beneficial side effects such as what I think I'm getting

from it?

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Melatonin is very inexpensive. But young people have lots of it. It's us

old fogies who no longer make enough of it. You have 30 years or so before

you need to concern yourself with it.

on 9/15/2003 4:14 PM, paultheo2000 at paultheo2000@... wrote:

> Is melatonin expensive? Is it useful for those who already have

> perfect or near perfect sleep?

>

> -

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This is my side effect of melatonin:

When I take melatonin every day for many month, I become to be in

sync with sun. Then at 8 pm, I want my bed ;) I stop to use it

because I have need make some overtime.

Now, I use it in dermal way. The name Melatonin mean than it is a

dermal hormone, and I think than can help my skin more in dermal way

than in oral

Bye

(and sorry for my english)

> As the veterans in the group know, I've often complained about

poor sleep.

> In the past I had tried melatonin and never noticed a difference

in sleep.

> A few days ago I again tried melatonin and am sleeping somewhat

better, not

> perfect, but better. It's possible I didn't take a high enough

dose in the

> past and even now perhaps I should take a bit more (I'm taking

about 2

> mgms).

>

> However I have noticed a tremendous increase in energy. I wake up

in the am

> raring to go (which is itself unusual as I've always been a slow

riser) and

> accomplish much more than I used to. Is anyone else taking

melatonin? If

> so, any beneficial side effects such as what I think I'm getting

from it?

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In a message dated 9/21/2003 4:03:50 AM Eastern Standard Time, dowlic@... writes:

By "dermal way," do you mean you take exogenous melatonin transdermally or

are you augmenting your endogenous melatonin via your sun exposure?

Thanks.

You guys are getting your melanins and your melatonins all mixed up. Sun exposure does not increase melatonin.

Winter

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By " dermal way, " do you mean you take exogenous melatonin transdermally or

are you augmenting your endogenous melatonin via your sun exposure?

Thanks.

" E-Mail is not to be used to pass on information or data. It should only

be used for company business. " --Dilbert

" Ahh, they have the internet on computers now " - Homer J. Simpson

" The human race has only one truely effective weapon, and that is laughter! "

- Mark Twain

>From: " leopardmike " <leopardmike@...>

>Reply-

>

>Subject: [ ] Re: melatonin

>Date: Sat, 20 Sep 2003 01:16:34 -0000

>

>This is my side effect of melatonin:

>When I take melatonin every day for many month, I become to be in

>sync with sun. Then at 8 pm, I want my bed ;) I stop to use it

>because I have need make some overtime.

>

>Now, I use it in dermal way. The name Melatonin mean than it is a

>dermal hormone, and I think than can help my skin more in dermal way

>than in oral

>

>Bye

>(and sorry for my english)

>

>

> > As the veterans in the group know, I've often complained about

>poor sleep.

> > In the past I had tried melatonin and never noticed a difference

>in sleep.

> > A few days ago I again tried melatonin and am sleeping somewhat

>better, not

> > perfect, but better. It's possible I didn't take a high enough

>dose in the

> > past and even now perhaps I should take a bit more (I'm taking

>about 2

> > mgms).

> >

> > However I have noticed a tremendous increase in energy. I wake up

>in the am

> > raring to go (which is itself unusual as I've always been a slow

>riser) and

> > accomplish much more than I used to. Is anyone else taking

>melatonin? If

> > so, any beneficial side effects such as what I think I'm getting

>from it?

>

>

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I'm not mixed up at all. I was simply asking a question. We have not been

discussing melanin.

Melatonin secretion can be suppressed by sun exposure, at least, and some

sun or light exposure may be required to help regulate melatonin secretion:

" Daily sun exposure enhances sleep. Lack of sleep results in daytime

fatigue. Melatonin, a natural hormone produced in the pineal gland of the

brain and the retina of the eye, enhances sleep, thereby energizing the

body. Daily exposure to bright sunlight increases the production of

melatonin and other pineal chemicals such as serotonin. The production of

melatonin is carefully regulated by the light-dark cycle. Peak melatonin

production only occurs at night, in a dark environment. Melatonin is not

stored in the body. Thus, we need a liberal supply each night to sleep well.

"

" Exposure to bright light, such as that emitted by the mid-day summer sun,

causes the brain to suppress the release of the hormone melatonin "

Also, the prior poster is correct:

" The sleep hormone (melatonin) and the anti-stress hormone (DHEA) are both

found in human skin. Both are converted to other entities with important

jobs to do. DHEA is converted into estrogen and androgen-type metabolites

found only in skin. Melatonin is synthesized in skin. In low concentrations

it can stimulate cell growth. This type of on-site, organ-specific

production of hormones is called intracrine biosynthesis. Intracrine

biosynthesis allows different organs to manufacture the substances they need

without flooding the entire body with growth factors. "

" Studies show that both DHEA and melatonin are absorbed by skin when applied

topically. A study from CHUL Research Center (in Canada) shows that the

activity of DHEA applied topically is 85-90% greater than when taken orally

(at least in rodents). No special carriers are needed to get DHEA and

melatonin into skin. A properly formulated topical preparation of melatonin

and DHEA will contain just enough hormone to benefit skin without providing

enough to escape into circulation. It makes sense to apply the hormones

directly to the skin if skin protection is the goal, since ingested hormones

may end up everywhere but the skin. "

" Melatonin is another antioxidant that protects against UV radiation. A

group at the University of Zurich has shown that topical melatonin gives

excellent protection against sunburn if applied before sun exposure.

Melatonin also appears to have a role in repairing burned skin. In a study

published in Brain Research Bulletin, melatonin levels rose 6 hours after

burn injury, then fell to normal. "

" E-Mail is not to be used to pass on information or data. It should only

be used for company business. " --Dilbert

" Ahh, they have the internet on computers now " - Homer J. Simpson

" The human race has only one truely effective weapon, and that is laughter! "

- Mark Twain

>From: WinterQQ@...

>Reply-

>

>Subject: Re: [ ] Re: melatonin

>Date: Sun, 21 Sep 2003 06:49:53 EDT

>

>In a message dated 9/21/2003 4:03:50 AM Eastern Standard Time,

>dowlic@... writes:

>

> > By " dermal way, " do you mean you take exogenous melatonin transdermally

>or

> > are you augmenting your endogenous melatonin via your sun exposure?

> >

> > Thanks.

> >

>

>You guys are getting your melanins and your melatonins all mixed up. Sun

>exposure does not increase melatonin.

>

>Winter

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> Dowling "

> By " dermal way, " do you mean you take exogenous melatonin

>transdermally or are you augmenting your endogenous melatonin via

>your sun exposure?

I take exogenous melatonin transdermally.

I takes a capsule of 1.5 mg which I dissolve in water and then I

apply to the skin with a moisturizing lotion.

It is possible because melatonin is very small and lipo-soluble

P.S. I make the same for the DHEA. Night with melatonin and morning

for DHEA.

I think than CRON is a good thing is health is excellent, to many

people forget the skin.

Bye

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That's what I thought.

Thanks for your reply.

" E-Mail is not to be used to pass on information or data. It should only

be used for company business. " --Dilbert

" Ahh, they have the internet on computers now " - Homer J. Simpson

" The human race has only one truely effective weapon, and that is laughter! "

- Mark Twain

>From: " leopardmike " <leopardmike@...>

>Reply-

>

>Subject: [ ] Re: melatonin

>Date: Mon, 22 Sep 2003 01:55:32 -0000

>

>

> > Dowling "

> > By " dermal way, " do you mean you take exogenous melatonin

> >transdermally or are you augmenting your endogenous melatonin via

> >your sun exposure?

>

>I take exogenous melatonin transdermally.

>

>I takes a capsule of 1.5 mg which I dissolve in water and then I

>apply to the skin with a moisturizing lotion.

>It is possible because melatonin is very small and lipo-soluble

>

>P.S. I make the same for the DHEA. Night with melatonin and morning

>for DHEA.

>

>I think than CRON is a good thing is health is excellent, to many

>people forget the skin.

>

>Bye

>

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Hello Francesca and CR ALL:

I take melatonin when I want to be certain to sleep well.

Take too much however, and you can be drowsy the next day.

Take the right amount just before bedtime, and you will

probably sleep well and wakeup energized. Trial and error

the dosage to fit your age and situation. I take 3 mg,

simply because 1 mg doesn't work quite as well for me.

If you exercise a lot on a given day, you normally sleep

quite well, and don't need melatonin. Also, if you eat a

high carb diet, you sleep better. If you cheat with

extra carbs on a low carb diet, esp before bed, or you

happen to eat a big or heavy meal, then you don't have as

much need to take melatonin to sleep better. Also eating

lightly just before bed (not too much) can help you

sleep better too.

Exercise invariably helps you sleep better. Taking

holidays from melatonin can be good, to achieve maximum

effectiveness and response when you want to achieve it.

-- Warren

====================================== ==============================

-----Original Message-----

From: Francesca Skelton [mailto:fskelton@...]

Sent: Monday, September 15, 2003 10:30 AM

support group

Subject: [ ] melatonin

As the veterans in the group know, I've often complained about poor sleep.

In the past I had tried melatonin and never noticed a difference in sleep.

A few days ago I again tried melatonin and am sleeping somewhat better, not

perfect, but better. It's possible I didn't take a high enough dose in the

past and even now perhaps I should take a bit more (I'm taking about 2

mgms).

However I have noticed a tremendous increase in energy. I wake up in the am

raring to go (which is itself unusual as I've always been a slow riser) and

accomplish much more than I used to. Is anyone else taking melatonin? If

so, any beneficial side effects such as what I think I'm getting from it?

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I've heard nothing but good about melatonin and I'm sure I would take

it if it weren't for the fact that my anti-depressant medication makes

me sleepy enough most nights.

-Dominick

> Hello Francesca and CR ALL:

>

> I take melatonin when I want to be certain to sleep well.

> Take too much however, and you can be drowsy the next day.

> Take the right amount just before bedtime, and you will

> probably sleep well and wakeup energized. Trial and error

> the dosage to fit your age and situation. I take 3 mg,

> simply because 1 mg doesn't work quite as well for me.

>

> [...]

>

> -- Warren

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  • 1 month later...

Peg: it's a different dosage for everyone. For me, I've found that 2 mg is

about right.

on 11/6/2003 2:51 PM, hsanborn2@... at hsanborn2@... wrote:

> I am hoping you will also tell us the dosage of melatonin you favor as your

> only supplement. Best, Peg

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