All It Takes is ONE Key Discovery for CR Payday

November 28, 2003

Hello CR ALL:

All it takes is *ONE* key discovery to change the Aging Equation.

Then we cash in. CR Payday has arrived. Now imagine a whole

sequence of such Paydays with break-thru discoveries. Then we

really cash in. We have struck gold, and hit the CR ***JACKPOT***.

For example, if the muscle atrophy (muscle wasting) due to aging

could be overcome, would that help restore youth? Sure!

In the News Today:

Making Old Muscles New Again -- Restoring Youth

===============================================

....A further set of experiments showed that slow repair in older muscles

can be overcome. When the team applied a molecule to young muscles that

blocked Delta, those satellite cells failed to divide in response to

damage. Conversely, when they applied a Delta-mimicking molecule to

injured, older muscles, satellite cells began dividing much like the

those in younger muscle. The older muscles with artificially activated

satellite cells had a regenerative ability comparable to that of

younger muscle.

Although the studies focused on muscle regeneration after injury, Rando

said similar problems with the interplay between Delta and Notch may

cause the gradual muscle atrophy that occurs in older people, in

astronauts or in people whose limbs are immobilized in a cast or from

bed rest.

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