Re: Spindler Proves CR Works in Old Animals

[Guest guest]

Warren: as a senior citizen, I appreciate knowing this. But even if it

hadn't been demonstrated in the lab, I'm healthier. I rarely get colds

anymore (and when I do, they're mild). And I used to get the stomach flu a

couple of times a year (nausea, fever, cold sweats and generally feeling

miserable). For me just bypassing the misery of being sick (even if I don't

live a day longer) while I'm living out my lifespan is worth every bit of

any " sacrifice " . And I find the longer I'm on CR, the easier it is.

on 10/10/2003 11:57 AM, Warren at warren.taylor@... wrote:

> ''Caloric restriction is the most robust environmental method known

> for decelerating aging and the development of age-related diseases.

> CR is also widely thought to be less effective in older animals.

> Using survival and high-density microarray studies, we demonstrate

> that CR acts rapidly and reversibly to establish a pattern of

> gene expression temporally associated with enhanced life span

> and reduced tumor incidence in mice. CR was fully effective at

> extending life span and reducing tumor incidence when begun in

> old animals. The results indicate that therapies mimicking the

> gene expression effects of CR may be rapidly effective, even

> in old animals.''

>

> The word temporary means that the CR effects remain, so long as

> the animal remains in a CR state.

>

> This is outstanding news for the middle-aged and senior citizens

> within our ranks. Here is wisdom: Cut calories, improve nutrition,

> live better, live longer, and be happy!

>

> -- Warren