Scientists Say Protein Extends Life of Worm

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A single protein could be a key to extending the normal life span of

worms and possibly humans, Swiss scientists said yesterday.

By knocking out a protein called TOR that regulates cell growth in the

nematode worm C. elegans, researchers at the University of Fribourg

extended its life span from 15 to 25 days.

" It has been suggested that maybe TOR could have an influence on

aging. We have proven it for the first time in C. elegans, " said Fritz

Mueller, who headed the team. " It is very likely that we may find similar

things in other species as well, but it remains to be proven. "

The protein, which is present in plants, animals and humans, regulates

metabolism and energy. It senses the availability of nutrients and

translates that into protein synthesis and cell growth.

Scientists have shown that drastically reducing calories consumed by

mice extends their life span. Mueller believes TOR could explain how it

happens.