Garlic's allicin prevents weight gain?

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Hi All,

The below is PDF-available from me, but 5 mg/kg body weights allicin

were used. How does this transtlate into realistic consumption?

Cheers, Alan.

Am J Hypertension

The effects of allicin on weight in fructose-induced

hyperinsulinemic, hyperlipidemic, hypertensive rats, Pages 1053-1056

Amitai Elkayam, Mirelman, Edna Peleg, Meir Wilchek, Talia

Miron, Aharon Rabinkov, Mor Oron-Herman and Talma Rosenthal

SummaryPlus | Full Text + Links | PDF (65 K)

Male Sprague-Dawley rats weighing 240 to 250 g were fed a fructose-

enriched diet consisting of 21% protein, 5% fat, 60% carbohydrate,

0.49% sodium and 0.49% potassium for 5 weeks, which produced

hyperinsulinemia, hypertension, and hypertriglyceridemia. Group I

(controls) rats were fed a diet enriched by fructose only; group II

was given allicin the last 2 weeks, and group III was given allicin

the first 3 weeks. The three groups consumed the same amount of food.

Weight was measured at the beginning of the experiment and after 3

and 5 weeks on the diet.

Results

Weight in the control group rose from 249.4 ± 10.04 g to 274.5 ± 15.5

g after 3 weeks and to 306.9 ± 22.2 g after 5 weeks. Weight in group

II rose from baseline 259.1 ± 12.1 g to 306.9 ± 22.2 g after 3 weeks

on fructose alone, and declined slightly to 282.4 ± 17.4 g after 2

weeks of allicin (P < .02). In group III, in which the protocol was

reversed, the baseline weight of 260.4 ± 13.25 g rose only to 269.8

±15.3 g (P < .431) after 3 weeks on fructose and allicin.

Conclusions

The control group that was fed a diet enriched by fructose alone

continued to gain weight, whereas the groups fed allicin did not. The

difficulty of preventing weight gain after reaching the nadir of

weight loss underscores the practical value of allicin for weight

control.