Two More Questions: CALORIES

[Guest guest]

Hi folks:

The successful CR experiments usually seem to entail 30% to 40%

calorie restriction. So we can probably be fairly sure that the

optimum restriction is somewhere between 25% and 45%.

First, am I right in believing no one has yet done the experiments

with mice on a variety of different degrees of restriction (say 25%

30% 35% 40% 45%) to find out what degree of restriction results in

the greatest life extension? (I think I know the answer to

this .... the work hasn't been done yet. Just checking.)

Second, whatever the optimal degree of restriction turns out to be,

is there a good way to determine the base calorie intake from which

the 40% reduction should be calculated? Are we talking about the

calorie level that is currently consistent with maintaining our set-

point weight? And if so, does that mean that everyone needs to spend

a few months determining how many calories that is before starting

out on CR? If so then I didn't do that, and so I don't know what

that base set-point calorie level is.

It would be nice to be able to determine what one's ideal CR calorie

intake should be. Especially if the curve is steep each side of the

optimal level, as previously noted it may be. The easiest answer may

be to experiment to see what level of calorie input is consistent

with one's chosen best guess criterion for optimal CR (Perhaps BMI

of 19, or BF% of 10% or 8% or whatever). But that would be just a

guess.

I suspect lots of us newer participants here must be wondering about

the answer to this question.

Rodney.