Re: high anti tpo and high thyroglobulin

[Guest guest]

Maghee,

You wrote:

> I have my bloodwork results and I was wondering if what high tpo and

> throglobulin meant....

You have Hashi's and excess binding.

> ... Also, I read that selenium may help lower the

> thyroglobulin....

That is an indirect effect, but you should take some anyway. Selenium mainly is

a key ingredient in the enzymes that convert T4 to T3. It also helps convert T3

to other Ts, so it reduces the total that needs to be bound, thus reducing the

globulin level.

You might want more selenium than is in a multivitamin, just try not to exceed

200 mcg per day for long periods.

> tsh 2.2

> t4 8.5

> t3 105

> tuptake 34

> anti tpo 121

> thyroglobulin 70.1

Please include reference ranges for your lab results. These vary depending on

the reagents used. If these are close to the common ones, you could use more

thyroid medication. How much more depends on what you are taking. Please be

specific.

Chuck

[Guest guest]

Chuck,

I think you know I have Hashi's, can you explain what you mean by

excess binding? How does it effect someone other than high TPO, TgAB?

Venizia

>

> > I have my bloodwork results and I was wondering if what high tpo and

> > throglobulin meant....

>

> You have Hashi's and excess binding.

>

> >

[Guest guest]

Hope this isn't a stupid question: How does one increase

thyroglobulin? By increasing med. dose?

Venizia

>

> >

> > I think you know I have Hashi's, can you explain what you mean by

> > excess binding? How does it effect someone other than high TPO, TgAB?

>

> About 99% of our T4 and T3 are tightly bound to globulin and albumin

proteins (enzymes). The type specific to T4 is called thyroglobulin.

This is the body's method for storing thyroxins in the blood, since

only the free fraction of T3, the FT3 is really active and able to get

across cell boundaries. If you have too much thyroglobulin, then your

free fraction will be low (much less than 1%) or difficult to

maintain. This makes you hypoT, even if the thyroid is still producing

T4.

>

> An increase in thyroglobulin may be a way to protect T4 in the blood

during an antibody attack, but it can also occur independently of

Hashi's.

>

> Chuck

>

[Guest guest]

hi Maghee, I wonder what just watching things is gonna do? goiter means you

need iodine, imagine that the doc doesn't know that?

http://www.helpmythyroid.com

http://www.optimox.com

you will need " enough " to shrink the goiter, not low dose stuff.

Gracia

Hi

I have my bloodwork results and I was wondering if what high tpo and

throglobulin meant. Also, I read that selenium may help lower the

thyroglobulin. Does anyone take selenium? I also have a rather large

goiter. Right now the doctor is just watching things. Is there

anything I can do to get more energy besides coffee.

My results were

tsh 2.2

t4 8.5

t3 105

tuptake 34

anti tpo 121

thyroglobulin 70.1

Any ideas or suggestions would be helpful.

Thanks

Maghee

[Guest guest]

With these numbers and high antibodies, I would find a different

doctor. You have Hashimoto thyroditis. I also have it. I take 200

mcg of selenium a day and Armour thyroid. Your doctor does not know

what he is doing. You are not going to get better watching and

waiting. I can't believe he said that to you. He didnt even do the

right tests. You should ask for Free T3 and Free T4. Most of us feel

better when the TSH is a " 0 " but most of us also do not even go by the

TSH. We go by the frees 3 and 4. You should go to the website

stopthethyroidmadness.com. It has an incredible amount of info.

Venizia

>

> Hi

> I have my bloodwork results and I was wondering if what high tpo and

> throglobulin meant. Also, I read that selenium may help lower the

> thyroglobulin. Does anyone take selenium? I also have a rather large

> goiter. Right now the doctor is just watching things. Is there

> anything I can do to get more energy besides coffee.

> My results were

> tsh 2.2

> t4 8.5

> t3 105

> tuptake 34

> anti tpo 121

> thyroglobulin 70.1

> Any ideas or suggestions would be helpful.

> Thanks

> Maghee

>

[Guest guest]

Suggested treatments for goiter by MAYO CLINIC:

http://www.mayoclinic.com/health/goiter/DS00217/DSECTION=6

_____

From: hypothyroidism [mailto:hypothyroidism ]

On Behalf Of Gracia

Sent: Saturday, June 14, 2008 12:40 AM

hypothyroidism

Subject: Re: high anti tpo and high thyroglobulin

hi Maghee, I wonder what just watching things is gonna do? goiter means you

need iodine, imagine that the doc doesn't know that?

http://www.helpmyth <http://www.helpmythyroid.com> yroid.com

http://www.optimox. <http://www.optimox.com> com

you will need " enough " to shrink the goiter, not low dose stuff.

Gracia

Hi

I have my bloodwork results and I was wondering if what high tpo and

throglobulin meant. Also, I read that selenium may help lower the

thyroglobulin. Does anyone take selenium? I also have a rather large

goiter. Right now the doctor is just watching things. Is there

anything I can do to get more energy besides coffee.

My results were

tsh 2.2

t4 8.5

t3 105

tuptake 34

anti tpo 121

thyroglobulin 70.1

Any ideas or suggestions would be helpful.

Thanks

Maghee

[Guest guest]

can any one comment?

Gracia

> >

> Transient Hypothyroidism or Persistent Hyperthyrotropinemia in Neonates

> Born to Mothers with Excessive Iodine Intake

>

> Soroku Nishiyama, Tomohiro Mikeda, Toshihisa Okada, Kimitoshi Nakamura,

> Tomio Kotani, Akira Hishinuma. Thyroid. December 1, 2004, 14(12):

> 1077-1083.

>

> Perinatal exposure to excess iodine can lead to transient hypothyroidism

> in the newborn. In Japan, large quantities of iodine-rich seaweed such

> as kombu (Laminaria japonica) are consumed. However, effects of iodine

> from food consumed during the perinatal period are unknown. The

> concentration of iodine in serum, urine, and breast milk in addition to

> thyrotropin (TSH), free thyroxine (FT4), and thyroglobulin was measured

> in 34 infants who were positive at congenital hypothyroidism screening.

> Based on the concentration of iodine in the urine, 15 infants were

> diagnosed with hyperthyrotropinemia caused by the excess ingestion of

> iodine by their mothers during their pregnancy. According to serum

> iodine concentrations, these infants were classified into group A (over

> 17 µg/dL) and group B (under 17 µg/dL) of serum iodine. During their

> pregnancies these mothers consumed kombu, other seaweeds, and instant

> kombu soups containing a high level of iodine. It was calculated that

> the mothers of group A infants ingested approximately 2300–3200 µg of

> iodine, and the mothers of group B infants approximately 820–1400 µg of

> iodine per day during their pregnancies. Twelve of 15 infants have

> required levo-thyroxine (LT4) because hypothyroxinemia or persistent

> hyperthyrotropinemia was present. In addition, consumption of iodine by

> the postnatal child and susceptibility to the inhibitory effect of

> iodine may contribute in part to the persistent hyperthyrotropinemia. We

> propose that hyperthyrotropinemia related to excessive iodine ingestion

> by the mother during pregnancy in some cases may not be transient.

>

> Complete paper:

> http://www.liebertonline.com/doi/abs/10.1089%2Fthy.2004.14.1077

>

> Chuck

>

> ------------------------------------

>

>

[Guest guest]

It makes me wonder if their seaweed products are filled with toxic halides

and arsenic like ours are. If that is the case then it would explain the

hypoT more than high iodine levels. I don't know toxicology issues in

Japan. Anyone else?

Fw: Re: high anti tpo and high thyroglobulin

>

> can any one comment?

> Gracia

>

>> >

>> Transient Hypothyroidism or Persistent Hyperthyrotropinemia in Neonates

>> Born to Mothers with Excessive Iodine Intake

>>

>> Soroku Nishiyama, Tomohiro Mikeda, Toshihisa Okada, Kimitoshi Nakamura,

>> Tomio Kotani, Akira Hishinuma. Thyroid. December 1, 2004, 14(12):

>> 1077-1083.

>>

>> Perinatal exposure to excess iodine can lead to transient hypothyroidism

>> in the newborn. In Japan, large quantities of iodine-rich seaweed such

>> as kombu (Laminaria japonica) are consumed. However, effects of iodine

>> from food consumed during the perinatal period are unknown. The

>> concentration of iodine in serum, urine, and breast milk in addition to

>> thyrotropin (TSH), free thyroxine (FT4), and thyroglobulin was measured

>> in 34 infants who were positive at congenital hypothyroidism screening.

>> Based on the concentration of iodine in the urine, 15 infants were

>> diagnosed with hyperthyrotropinemia caused by the excess ingestion of

>> iodine by their mothers during their pregnancy. According to serum

>> iodine concentrations, these infants were classified into group A (over

>> 17 µg/dL) and group B (under 17 µg/dL) of serum iodine. During their

>> pregnancies these mothers consumed kombu, other seaweeds, and instant

>> kombu soups containing a high level of iodine. It was calculated that

>> the mothers of group A infants ingested approximately 2300–3200 µg of

>> iodine, and the mothers of group B infants approximately 820–1400 µg of

>> iodine per day during their pregnancies. Twelve of 15 infants have

>> required levo-thyroxine (LT4) because hypothyroxinemia or persistent

>> hyperthyrotropinemia was present. In addition, consumption of iodine by

>> the postnatal child and susceptibility to the inhibitory effect of

>> iodine may contribute in part to the persistent hyperthyrotropinemia. We

>> propose that hyperthyrotropinemia related to excessive iodine ingestion

>> by the mother during pregnancy in some cases may not be transient.

>>

>> Complete paper:

>> http://www.liebertonline.com/doi/abs/10.1089%2Fthy.2004.14.1077

>>

>> Chuck

>>

>> ------------------------------------

>>

>>

[Guest guest]

The data on iodine consumption in Japan (via seaweed), and it's multiple health

benefits

seems to be the core rational that got Dr. Abraham to research this topic. I

don't think

toxic seaweed is the cause of this phenomenon. Additionally, since seaweed is

such a

great chelator, Drum (ryandrum.com - very sharp seaweed and thyroid expert)

theorizes that even if the seaweed harbors heavy metals, it's most likely to

travel through

the digestive system without releasing the toxins. If these newborns had high

thyroid

antibodies, then they had Hashimoto's, which would add some fuel to the concerns

about

iodine consumption and Hashi's.

PS: If you're looking for a clean source of seaweed, try nature sprit herbs -

http://www.naturespiritherbs.com/ or Maine coast Seaweeds

>

> It makes me wonder if their seaweed products are filled with toxic halides

> and arsenic like ours are. If that is the case then it would explain the

> hypoT more than high iodine levels. I don't know toxicology issues in

> Japan. Anyone else?

>

>

>

>

> Fw: Re: high anti tpo and high thyroglobulin

>

>

> >

> > can any one comment?

> > Gracia

> >

> >> >

> >> Transient Hypothyroidism or Persistent Hyperthyrotropinemia in Neonates

> >> Born to Mothers with Excessive Iodine Intake

> >>

> >> Soroku Nishiyama, Tomohiro Mikeda, Toshihisa Okada, Kimitoshi Nakamura,

> >> Tomio Kotani, Akira Hishinuma. Thyroid. December 1, 2004, 14(12):

> >> 1077-1083.

> >>

> >> Perinatal exposure to excess iodine can lead to transient hypothyroidism

> >> in the newborn. In Japan, large quantities of iodine-rich seaweed such

> >> as kombu (Laminaria japonica) are consumed. However, effects of iodine

> >> from food consumed during the perinatal period are unknown. The

> >> concentration of iodine in serum, urine, and breast milk in addition to

> >> thyrotropin (TSH), free thyroxine (FT4), and thyroglobulin was measured

> >> in 34 infants who were positive at congenital hypothyroidism screening.

> >> Based on the concentration of iodine in the urine, 15 infants were

> >> diagnosed with hyperthyrotropinemia caused by the excess ingestion of

> >> iodine by their mothers during their pregnancy. According to serum

> >> iodine concentrations, these infants were classified into group A (over

> >> 17 µg/dL) and group B (under 17 µg/dL) of serum iodine. During their

> >> pregnancies these mothers consumed kombu, other seaweeds, and instant

> >> kombu soups containing a high level of iodine. It was calculated that

> >> the mothers of group A infants ingested approximately 2300–3200 µg of

> >> iodine, and the mothers of group B infants approximately 820–1400 µg of

> >> iodine per day during their pregnancies. Twelve of 15 infants have

> >> required levo-thyroxine (LT4) because hypothyroxinemia or persistent

> >> hyperthyrotropinemia was present. In addition, consumption of iodine by

> >> the postnatal child and susceptibility to the inhibitory effect of

> >> iodine may contribute in part to the persistent hyperthyrotropinemia. We

> >> propose that hyperthyrotropinemia related to excessive iodine ingestion

> >> by the mother during pregnancy in some cases may not be transient.

> >>

> >> Complete paper:

> >> http://www.liebertonline.com/doi/abs/10.1089%2Fthy.2004.14.1077

> >>

> >> Chuck

> >>

> >> ------------------------------------

> >>

> >>