Guest guest Posted September 3, 2008 Report Share Posted September 3, 2008 Ask for Armour. You have to study www.stopthethyroidmadness.com to know about Armour and dosing. You will start off slow and work your way up so be ready to get better, but slowly. You may also be experiencing adrenal fatigue (which you can also read about on STTM). You'll need a saliva test for that (blood isn't reliable). AFAIK there is no virus that causes hypo. Hashimoto is autoimmune which explains your hot/cold cycles. With hashi's, your body attacks your thyroid and eventually destroys it. I believe a renewed mind will help your thyroid. Keep us updated CW -- hey guys need ur help Hi i'm new to the list and new to the thyroid thing. I had a bunch of testing done and haven't gotten it back yet. All i know is 1st round of testing showed low thyroid and hyshimoto was normal. He wanted to put me on synthroid (75) after my testing was done. I started it last week so i've been on it for about a week. I think my symptoms have gotten worse... I feel like my neck is swollen, glands are swollen, face is swollen, tongue is swollen, dusty dry eyes, I haven't slept (total insomnia) ALL WEEK, used 2b hot all the time now i'm cold all the time, crying all the time particularly after taking the med, and my ovaries and bones hurt. I called the doc today to tell him about it and wanted to know what my test results showed. He told me he'd only talk to me in the office (which is 3 weeks from now) and continue the med, and the thyroid ultrasound showed a goiter. I told the nurse that called me back he can stick his synthroid up his you know what I'm not taking it for 3 weeks and going through more of this. I almost passed out at the store tonight. I didn't think i was being unreasonable by asking for a different thyroid med?? Do you?? I'm gonna call next week and b more of a PITA ... any ideas which thyroid med I should ask for?? I also have lyme with a weak liver and don't do real well with pharmasuticals. I'm real sensitive. I have a rife machine and have been using some numbers. Any ideas what the name of the virus is that causes the hypo??? is it that surpa? If I know what it is i know how to kill it. Thanks in advance. Carol Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 3, 2008 Report Share Posted September 3, 2008 Carol, You wrote: > He wanted to > put me on synthroid (75) after my testing was done. I started it last > week so i've been on it for about a week. I think my symptoms have > gotten worse... That is a common reaction during titration called an oscillation. Basically you don't have a large enough dose yet to stop your symptoms, and it takes several weeks for the levels to build in your system. I do think you have enough symptoms to request an early test for the next step in the titration, if you can get the doctor to let you in. Your heart needs to be in good shape to do that, otherwise he would not have started you at 75 mcg. The T4 in your medication will not affect your liver. > ... Any ideas what the name of > the virus is that causes the hypo??? HypoT is not caused by a virus. Chuck Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 3, 2008 Report Share Posted September 3, 2008 So if I have a goiter which affects my thyroid,and the family or organizms that cause the goiter is called a struma, then what is a struma if it's not a virus?? Is it a bacteria?? Or a parasite?? What exactly is it?? Anyone know?? Carol Struma (family of organisms that can infect the thyroid causing goiter. Use kelp internally. Use Struma cystica, nodosa, and parenchyme freqs.) Struma cystica - 5311, 531, 756, 361 Struma nodosa - 105, 122, 321, 517, 532, 651, 714 Struma parenchyme - 121, 576 >>... Any ideas what the name of >>the virus is that causes the hypo??? >> >> > >HypoT is not caused by a virus. > >Chuck > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 3, 2008 Report Share Posted September 3, 2008 I've wondered why anyone who has no problem converting T4 to T3 would need Armour; especially since only a small percentage have this problem. What's the reason? Thanks, > Posted by: " Crystal " sweetnwright@... > <mailto:sweetnwright@...?Subject=%20Re%3A%20hey%20guys%20need%20ur%20help> > sweetenloe1 <sweetenloe1> > > > Wed Sep 3, 2008 10:45 am (PDT) > > Ask for Armour. You have to study www.stopthethyroidm > adness.com to know > about Armour and dosing. You will start off slow and work your way up > so be > ready to get better, but slowly. You may also be experiencing adrenal > fatigue (which you can also read about on STTM). You'll need a saliva test > for that (blood isn't reliable). AFAIK there is no virus that causes > hypo. > Hashimoto is autoimmune which explains your hot/cold cycles. With hashi's, > your body attacks your thyroid and eventually destroys it. I believe a > renewed mind will help your thyroid. Keep us updated > CW Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 4, 2008 Report Share Posted September 4, 2008 Carol, You wrote: > > So if I have a goiter which affects my thyroid,and the family or > organizms that cause the goiter is called a struma, then what is a > struma if it's not a virus?? Is it a bacteria?? Or a parasite?? Struma is a neoplasm, another name for goiter. No bacteria or virus is involved. Chuck Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 4, 2008 Report Share Posted September 4, 2008 Thanks Chuck. There are so many fun things that can live in our body aren't there?? Carol > > > > So if I have a goiter which affects my thyroid,and the family or > > organizms that cause the goiter is called a struma, then what is a > > struma if it's not a virus?? Is it a bacteria?? Or a parasite?? > > Struma is a neoplasm, another name for goiter. No bacteria or virus is > involved. > > Chuck > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 7, 2008 Report Share Posted September 7, 2008 can you post your FT3? Gracia I've wondered why anyone who has no problem converting T4 to T3 would need Armour; especially since only a small percentage have this problem. What's the reason? Thanks, > Recent Activity a.. 20New Members Visit Your Group Meditation and Lovingkindness A Group to share and learn. Health Healthy Aging Improve your quality of life. 10 Day Club on Share the benefits of a high fiber diet. . ------------------------------------------------------------------------------ No virus found in this incoming message. Checked by AVG - http://www.avg.com Version: 8.0.169 / Virus Database: 270.6.17/1655 - Release Date: 9/5/2008 7:05 PM Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 7, 2008 Report Share Posted September 7, 2008 LOL how many of us have wanted to tell a doc to shove his_____ up his ____. do the rife machine and also try Iodoral http://www.drbrownstein.com http://www.optimox.com Gracia Hi i'm new to the list and new to the thyroid thing. I had a bunch of testing done and haven't gotten it back yet. All i know is 1st round of testing showed low thyroid and hyshimoto was normal. He wanted to put me on synthroid (75) after my testing was done. I started it last week so i've been on it for about a week. I think my symptoms have gotten worse... I feel like my neck is swollen, glands are swollen, face is swollen, tongue is swollen, dusty dry eyes, I haven't slept (total insomnia) ALL WEEK, used 2b hot all the time now i'm cold all the time, crying all the time particularly after taking the med, and my ovaries and bones hurt. I called the doc today to tell him about it and wanted to know what my test results showed. He told me he'd only talk to me in the office (which is 3 weeks from now) and continue the med, and the thyroid ultrasound showed a goiter. I told the nurse that called me back he can stick his synthroid up his you know what I'm not taking it for 3 weeks and going through more of this. I almost passed out at the store tonight. I didn't think i was being unreasonable by asking for a different thyroid med?? Do you?? I'm gonna call next week and b more of a PITA ... any ideas which thyroid med I should ask for?? I also have lyme with a weak liver and don't do real well with pharmasuticals. I'm real sensitive. I have a rife machine and have been using some numbers. Any ideas what the name of the virus is that causes the hypo??? is it that surpa? If I know what it is i know how to kill it. Thanks in advance. Carol ------------------------------------------------------------------------------ No virus found in this incoming message. Checked by AVG - http://www.avg.com Version: 8.0.169 / Virus Database: 270.6.17/1655 - Release Date: 9/5/2008 7:05 PM Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 8, 2008 Report Share Posted September 8, 2008 Hi Carol, You don't happen to be in New Zealand do you? Your list of reactions sounds like what a lot of people over there are experiencing from a new synthetic version of T4 which is produced by some sort of genetic modification. The drug company says there's no problem with it - it works fine in their laboratory - all the people getting sicker, losing their jobs and having accidents are apparently not relevant... Gail. PS Thanks for the information on Iodine Gracia - it's making a difference to me - but not at the doses you seem to be able to use. hypothyroidism@...: circe@...: Mon, 8 Sep 2008 00:08:46 -0400Subject: Re: hey guys need ur help LOL how many of us have wanted to tell a doc to shove his_____ up his ____.do the rife machine and also try Iodoralhttp://www.drbrownstein.com http://www.optimox.com GraciaHi i'm new to the list and new to the thyroid thing. I had a bunch oftesting done and haven't gotten it back yet. All i know is 1st roundof testing showed low thyroid and hyshimoto was normal. He wanted toput me on synthroid (75) after my testing was done. I started it lastweek so i've been on it for about a week. I think my symptoms havegotten worse... I feel like my neck is swollen, glands are swollen,face is swollen, tongue is swollen, dusty dry eyes, I haven't slept(total insomnia) ALL WEEK, used 2b hot all the time now i'm cold allthe time, crying all the time particularly after taking the med, andmy ovaries and bones hurt. I called the doc today to tell him aboutit and wanted to know what my test results showed. He told me he'donly talk to me in the office (which is 3 weeks from now) and continuethe med, and the thyroid ultrasound showed a goiter. I told the nursethat called me back he can stick his synthroid up his you know whatI'm not taking it for 3 weeks and going through more of this. Ialmost passed out at the store tonight. I didn't think i was beingunreasonable by asking for a different thyroid med?? Do you?? I'mgonna call next week and b more of a PITA ... any ideas which thyroidmed I should ask for?? I also have lyme with a weak liver and don't doreal well with pharmasuticals. I'm real sensitive. I have a rifemachine and have been using some numbers. Any ideas what the name ofthe virus is that causes the hypo??? is it that surpa? If I know whatit is i know how to kill it.Thanks in advance.Carol----------------------------------------------------------No virus found in this incoming message.Checked by AVG - http://www.avg.com Version: 8.0.169 / Virus Database: 270.6.17/1655 - Release Date: 9/5/2008 7:05 PM Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 8, 2008 Report Share Posted September 8, 2008 I thought you don't believe in labs? -- Re: Re: hey guys need ur help can you post your FT3? Gracia I've wondered why anyone who has no problem converting T4 to T3 would need Armour; especially since only a small percentage have this problem. What's the reason? Thanks, > Recent Activity a.. 20New Members Visit Your Group Meditation and Lovingkindness A Group to share and learn. Health Healthy Aging Improve your quality of life. 10 Day Club on Share the benefits of a high fiber diet. .. ---------------------------------------------------------- No virus found in this incoming message. Checked by AVG - http://www.avg.com Version: 8.0.169 / Virus Database: 270.6.17/1655 - Release Date: 9/5/2008 7:05 PM Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 8, 2008 Report Share Posted September 8, 2008 Good Morning, ~ Besides the additional benefit of Armour's additional ingredients of T3, T2, T1, and calcitonin, many people simply prefer a non-synthetic product. No different than choosing a vitamin supplement made from organic, raw processed vegetables vs. synthetic vitamins. Organic butter vs. margarine. Whole grain sprouted bread vs. Wonder Bread. Grass-fed beef vs. a Big Mac. Non-GMO foods vs. GMO. Dessicated thyroid vs. synthetic thyroid. Which do you think your body would prefer? take care, ~ I've wondered why anyone who has no problem converting T4 to T3 would need Armour; especially since only a small percentage have this problem. What's the reason? Thanks, Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 8, 2008 Report Share Posted September 8, 2008 it's also a myth that most peeps do fine on T4 alone. you have to know what to look for however. Gracia Good Morning, ~ Besides the additional benefit of Armour's additional ingredients of T3, T2, T1, and calcitonin, many people simply prefer a non-synthetic product. No different than choosing a vitamin supplement made from organic, raw processed vegetables vs. synthetic vitamins. Organic butter vs. margarine. Whole grain sprouted bread vs. Wonder Bread. Grass-fed beef vs. a Big Mac. Non-GMO foods vs. GMO. Dessicated thyroid vs. synthetic thyroid. Which do you think your body would prefer? take care, ~ I've wondered why anyone who has no problem converting T4 to T3 would need Armour; especially since only a small percentage have this problem. What's the reason? Thanks, ------------------------------------------------------------------------------ No virus found in this incoming message. Checked by AVG - http://www.avg.com Version: 8.0.169 / Virus Database: 270.6.19/1659 - Release Date: 9/8/2008 7:01 AM Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 8, 2008 Report Share Posted September 8, 2008 no I don't " believe in " labs except as an initial/early evaluation tool, but FT3 andFT4 have more relevance than TSH. I just wondered what his FT3 level was considering he is on T4 med and thinks that is all he needs. Gracia I thought you don't believe in labs? -- Re: Re: hey guys need ur help can you post your FT3? Gracia I've wondered why anyone who has no problem converting T4 to T3 would need Armour; especially since only a small percentage have this problem. What's the reason? Thanks, Recent Activity a.. 10New Members Visit Your Group Health Early Detection Know the symptoms of breast cancer. Meditation and Lovingkindness A Group to share and learn. Drive Traffic Sponsored Search can help increase your site traffic. . ------------------------------------------------------------------------------ No virus found in this incoming message. Checked by AVG - http://www.avg.com Version: 8.0.169 / Virus Database: 270.6.19/1659 - Release Date: 9/8/2008 7:01 AM Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 8, 2008 Report Share Posted September 8, 2008 , That is a solid case for ³natural² but you have to admit natural does NOT always mean healthy. I am a HUGE advocate of organic, non GMO foods but not all natural = the best: Poison ivy vs silk flowers to have in your house Stepping on a sting ray in the ocean vs a plastic bottle A dog bite from a rabid dog vs a paper cut Pig thryoid vs Bioidentical hormone ‹ not just a personal choice. People react badly to pig thryoid hormone. I know I do. There¹s so many natural things our bodies do not accept, like or react well to. That awareness alone is worth the existence of any of these boards. sue On 9/8/08 7:06 AM, " liebs8181 " <liebs8181@...> wrote: > > > > Good Morning, ~ > > Besides the additional benefit of Armour's additional ingredients of T3, T2, > T1, and calcitonin, many people simply prefer a non-synthetic product. > > No different than choosing a vitamin supplement made from organic, raw > processed vegetables vs. synthetic vitamins. > Organic butter vs. margarine. > Whole grain sprouted bread vs. Wonder Bread. > Grass-fed beef vs. a Big Mac. > Non-GMO foods vs. GMO. > > Dessicated thyroid vs. synthetic thyroid. > > Which do you think your body would prefer? > > take care, > ~ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 8, 2008 Report Share Posted September 8, 2008 If the so called peeps feel absolutely fine (your advice is to treat by symptoms) then how can it be a " myth " that they are doing fine on T4 alone? This is such contradictory posting.??? BTW Chuck tells us that Synthroid is also 'natural'..... though it would be impossible for me to repeat it in an intelligible form!!! DS Re: Re: hey guys need ur help it's also a myth that most peeps do fine on T4 alone. you have to know what to look for however. Gracia snip snip snip snip Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 8, 2008 Report Share Posted September 8, 2008 I don't know if I even have it. Since I'm symptom free I don't know if it's even been ordered... .. .. > > Posted by: " Gracia " circe@... > <mailto:circe@...?Subject=%20Re%3A%20hey%20guys%20need%20ur%20help> > graciabee <graciabee> > > > Sun Sep 7, 2008 8:01 pm (PDT) > > > can you post your FT3? > Gracia > > I've wondered why anyone who has no problem converting T4 to T3 would > need Armour; especially since only a small percentage have this > problem. What's the reason? > > Thanks, > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 8, 2008 Report Share Posted September 8, 2008 My understanding [i believe from Chuck] is that the molecule from Synthroid is bioidentical to that produced by the thyroid gland, and to that found in Armour. If so your body cannot tell the difference between the molecule from Synthroid and any other bioidentical one. And basically AFAIK T1 and T2 are waste products with no known benefit. That leaves T3 and calcitonin, and I don't know much if anything about calcitonin; but unless it's a major benefit then the major benefit would seem to be T3. But T3 is easily converted from T4 by [as I understand it] a very large majority of patients. So I'm having a hard time understanding why someone would want to take T3 as well as T4 if all they need is T4. As for " natural " I think it's very much misunderstood. The natural thing to do if you cannot produce T4 is to go into Myxedema coma and die a very lingering, painful death. Not exactly preferred by most people I suspect... I suspect my body does fine with Synthroid, as I have no symptoms. I think it's what Chuck and his relatives all take [and maybe his dog] but I'm not sure. Any any event if the things you don't like were fatal I doubt I'd have lived to 67! [ggg] .. .. > > Posted by: " liebs8181 " liebs8181@... > <mailto:liebs8181@...?Subject=%20Re%3A%20hey%20guys%20need%20ur%20help> > rcll8181 <rcll8181> > > > Mon Sep 8, 2008 5:06 am (PDT) > > Good Morning, ~ > > Besides the additional benefit of Armour's additional ingredients of > T3, T2, > T1, and calcitonin, many people simply prefer a non-synthetic product. > > No different than choosing a vitamin supplement made from organic, raw > processed vegetables vs. synthetic vitamins. > Organic butter vs. margarine. > Whole grain sprouted bread vs. Wonder Bread. > Grass-fed beef vs. a Big Mac. > Non-GMO foods vs. GMO. > > Dessicated thyroid vs. synthetic thyroid. > > Which do you think your body would prefer? > > take care, > ~ > > I've wondered why anyone who has no problem converting T4 to T3 would need > Armour; especially since only a small percentage have this problem. What's > the reason? > > Thanks, > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 8, 2008 Report Share Posted September 8, 2008 Hogwash. If you only take Synthroid because you cannot produce T4 then ALL of the T3 in your body after a short time has been converted by your body from T4. And that is very easy to measure. I'd like to see a CREDIBLE number of the percentage of patients who cannot produce T3 from T4. There are some patients who have binding problems and maybe RT3 problems, which I really don't understand. Or maybe they need Calcitonin; I don't know??? .. .. > > Posted by: " Gracia " circe@... > <mailto:circe@...?Subject=%20Re%3A%20hey%20guys%20need%20ur%20help> > graciabee <graciabee> > > > Mon Sep 8, 2008 6:49 am (PDT) > > > it's also a myth that most peeps do fine on T4 alone. you have to know > what to look for however. > Gracia Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 8, 2008 Report Share Posted September 8, 2008 you are just repeating what Chuck says. a good doc can identify symptoms as well as test the Frees. what is your FT3? holistic docs always use Armour or it's equivelent. and that is what Stopt the Thyroid madness website and book are all about. http://www.stopthethyroidmadness.com Gracia Hogwash. If you only take Synthroid because you cannot produce T4 then ALL of the T3 in your body after a short time has been converted by your body from T4. And that is very easy to measure. I'd like to see a CREDIBLE number of the percentage of patients who cannot produce T3 from T4. There are some patients who have binding problems and maybe RT3 problems, which I really don't understand. Or maybe they need Calcitonin; I don't know??? . . Recent Activity a.. 10New Members Visit Your Group Health Asthma Triggers How you can identify them. Meditation and Lovingkindness A Group to share and learn. Moderator Central An online resource for moderators of . . ------------------------------------------------------------------------------ No virus found in this incoming message. Checked by AVG - http://www.avg.com Version: 8.0.169 / Virus Database: 270.6.19/1659 - Release Date: 9/8/2008 7:01 AM Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 8, 2008 Report Share Posted September 8, 2008 there are many symptoms of low T3--big ones are weight and mood, exercise intolerance. Gracia I don't know if I even have it. Since I'm symptom free I don't know if it's even been ordered... . . > > Posted by: " Gracia " circe@... > <mailto:circe@...?Subject=%20Re%3A%20hey%20guys%20need%20ur%20help> > graciabee <graciabee> > > > Sun Sep 7, 2008 8:01 pm (PDT) > > > can you post your FT3? > Gracia > > I've wondered why anyone who has no problem converting T4 to T3 would > need Armour; especially since only a small percentage have this > problem. What's the reason? > > Thanks, > ------------------------------------------------------------------------------ No virus found in this incoming message. Checked by AVG - http://www.avg.com Version: 8.0.169 / Virus Database: 270.6.19/1659 - Release Date: 9/8/2008 7:01 AM Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 8, 2008 Report Share Posted September 8, 2008 Hmmmm.... " always " ????? My cousins holistic doc has her on Synthroid and Cytomel and she's doing just fine. DS Re: Re: hey guys need ur help you are just repeating what Chuck says. a good doc can identify symptoms as well as test the Frees. what is your FT3? holistic docs always use Armour or it's equivelent. and that is what Stopt the Thyroid madness website and book are all about. http://www.stopthethyroidmadness.com Gracia Hogwash. If you only take Synthroid because you cannot produce T4 then ALL of the T3 in your body after a short time has been converted by your body from T4. And that is very easy to measure. I'd like to see a CREDIBLE number of the percentage of patients who cannot produce T3 from T4. There are some patients who have binding problems and maybe RT3 problems, which I really don't understand. Or maybe they need Calcitonin; I don't know??? . . Recent Activity a.. 10New Members Visit Your Group Health Asthma Triggers How you can identify them. Meditation and Lovingkindness A Group to share and learn. Moderator Central An online resource for moderators of . . ---------------------------------------------------------------------------- -- No virus found in this incoming message. Checked by AVG - http://www.avg.com Version: 8.0.169 / Virus Database: 270.6.19/1659 - Release Date: 9/8/2008 7:01 AM Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 8, 2008 Report Share Posted September 8, 2008 I take levo/cyto and my goiter shunk and my thyroid is doing fine. It¹s my adrenals now I need to address. sue On 9/8/08 4:18 PM, " Dusty " <dusty@...> wrote: > > > > Hmmmm.... " always " ????? My cousins holistic doc has her on Synthroid and > Cytomel and she's doing just fine. > > DS > > Re: Re: hey guys need ur help > > you are just repeating what Chuck says. a good doc can identify symptoms > as well as test the Frees. what is your FT3? > holistic docs always use Armour or it's equivelent. and that is what > Stopt the Thyroid madness website and book are all about. > http://www.stopthethyroidmadness.com > Gracia > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 8, 2008 Report Share Posted September 8, 2008 According to someone I know I should treat to symptoms. Since what I'm doing leaves me symptom free according to that expert I don't need anything else! [ggg] You can find a lot of the same material posted by Chuck on a lot of sites. Just not the ones recommended by the iodine docs... .. .. > > Posted by: " Gracia " circe@... > <mailto:circe@...?Subject=%20Re%3A%20hey%20guys%20need%20ur%20help> > graciabee <graciabee> > > > Mon Sep 8, 2008 10:56 am (PDT) > > > you are just repeating what Chuck says. a good doc can identify > symptoms as well as test the Frees. what is your FT3? > holistic docs always use Armour or it's equivelent. and that is what > Stopt the Thyroid madness website and book are all about. > http://www.stopthethyroidmadness.com > <http://www.stopthethyroidmadness.com> > Gracia > > Hogwash. If you only take Synthroid because you cannot produce T4 then > ALL of the T3 in your body after a short time has been converted by your > body from T4. And that is very easy to measure. I'd like to see a > CREDIBLE number of the percentage of patients who cannot produce T3 > from T4. > > There are some patients who have binding problems and maybe RT3 > problems, which I really don't understand. Or maybe they need > Calcitonin; I don't know??? > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 8, 2008 Report Share Posted September 8, 2008 Sure. And about 10,000 other ailments. .. .. > > Posted by: " Gracia " circe@... > <mailto:circe@...?Subject=%20Re%3A%20hey%20guys%20need%20ur%20help> > graciabee <graciabee> > > > Mon Sep 8, 2008 11:00 am (PDT) > > > there are many symptoms of low T3--big ones are weight and mood, > exercise intolerance. > Gracia Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 9, 2008 Report Share Posted September 9, 2008 Hi , > " And basically AFAIK T1 and T2 are waste products with no known benefit. " Just like you - many endocrinologists also believe there is little (or no) known benefit or information about the other thyroid hormones 3, 5-diiodo-l-thyronine (T2) and monoiodothyronine (T1). This is not the case and because I appreciate your need for references, here are some. The manufacturers of Armour (Forest Pharmaceuticals) have done no studies into the specific amount of T2, T1, calcitonin or any other `T' hormones that are naturally occurring in the desiccated thyroid. Nothing has been removed in the processing. Because no studies have been done, this does not mean that T3,T1 and calcitonin are not active. There may be advantages to using Armour that are not related to its T3 content. Broda observed some patients treated with syntheticT4/T3 combination continued to experience residual symptoms, particularly dry skin and oedema. Both symptoms resolved in 1-2 months when the treatment was changed to Armour. (1) This observation suggests a third active substance is secreted by the thyroid gland. The most likely candidate is diiodotyrosine(T2). Although little was known about the function of this compound in humans, the widely held assumption that it is metabolically inert may be incorrect. In a study of guinea pigs, oral administration of T2 prevented alterations in thyroid and pituitary function induced by oophorectom (2). Administration of T2 also accelerated the metamorphosis of tadpoles and enhanced the growth of the protozoan Tetrahymena. (3, 4) Whole thyroid extracts contain T4 and T3, and also T2 and T1, which also have hormonal activity.(5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17) As seen already, T2 is very active in its metabolic effects.(5) T2 has been shown to increase hepatic oxygen consumption by about 30%. The authors of the study discovered that out of T4, T3 and T2, only T2 was active in stimulating rapid hepatic oxygen consumption. They concluded that it acts rapidly and directly through activation of the mitochondria.(6) In another study, T3 and T2 were compared in terms of Resting Metabolism (RM) and on the oxidative capacity of tissues that are metabolically active (liver, muscle tissue, brown adipose tissue or BAT, and heart). What they found was that T2 had a dose-dependent effect, which increased RM and oxidative capacity. They found the greatest response to T2 was in the liver and in BAT. The effects again occurred rapidly and independently of protein synthesis. They stated that their results suggested isomers like T2 could be direct mediators of thyroid hormone regulation on energy metabolism.(7, 8) A further study found increased hepatic oxidative capacity and thought this was due to a direct action upon the mitochondria by T2.(9) Other studies had similar findings.(10, 11) Yet another study showed the same thing: increased oxidative capacity and energy expenditure, causing the authors to suggest that T2 and T3 displayed similar effects.(12) T2 was also shown to have a similar effect to that of T3 on lipid metabolism with T2 actually doing a little better in some tissue.(13) Although there is little research in humans, some does exist. In one study, using human mononuclear blood cells, it was found that T2 increased the rate of respiration significantly.(15) So, the efficacy appears to have been established. Can it significantly inhibit TSH like T3 and T4? The studies are conflicting, but one thing seems to be prevalent amongst them all - TSH inhibition isn't nearly as severe with T2 as it is with T3.(14) One study showed that T2 is 13% less inhibitory on TSH levels, as compared to T3.(15) In yet another study, T3 and T2 suppressed TSH to similar levels; however, it took 15 mcg/100g body weight per day of T3 to accomplish this, while it took 200 mcg/100g body weight per day of T2 to accomplish the same thing. This means it took about 13 times more T2 to exert the same effect on TSH as T3.(16) When researchers in another study administered 100 ug/kg of T3 and 800-1600 ug/kg of T2 the following occurred: T3 rapidly decreased serum TSH levels to within minimal levels after 24 hours. Seventy-two hours after application, TSH levels were still significantly lower than control levels. As far as the T2, TSH levels were transiently reduced and reached their lowest point at 24 hours and increased afterwards. Basal levels were reached 72 hours after an application. What they found after analysing the data was that there seemed to be a trend for a dose-dependent suppression of TSH by T2, which did not reach statistical significance. Furthermore, it appears as though it took 100 times more T2 than T3 to finally exert the same amount of TSH inhibition. Even using 400 times more T2 than T3, it appears that T3 only allows TSH to be inhibited to just a slight degree less than T2.(17) Refs: 1) BO. " Is there a third hormone in the thyroid gland? Which preparation should be used for treatment? " J Int Acad Prev Med 1982; November:38-39. 2) Loeser A. " Thyroid and ovary " . Journal of the American Medical Association 1935;104: 870. 3) Morse M. " The effective principle in thyroid accelerating involution in frog larvae " . J Biol Chem 1914;19:421-429 4) Csaba G, Nemeth G. " Enhancement of the sensitivity of Tetrahymena to a second hormonal influence by hormone pre-treatment " . Acta Biol Med Ger 1980;39:1027-1030 5) Shames, RL, Shames, KH, Thyroid Power: 10 Steps to Total Health, Harper Publishers, New York, 2001. 6) Rothfeld, G.S., Romaine, D.S., " Thyroid Balance: Traditional and Alternative Methods for Treating Thyroid Disorders " , Media Corporation, Avon, Massachusetts, USA, 2003. 7) Brownstein, D., Overcoming Thyroid Disorders, Medical Alternatives Press, 2002. 8) Lombardi, A.Lanni, A.Silvestri,E. de Lange, P.Goglia, F.Moreno,M. 3, 5Diiodothyronine: Biological Actions and Therapeutic Perspectives. pp.255-265 (11) 9) Lanni A et.al. " 3,5-diiodo-l-thyroxine (T2) reduces adiposity and body weight gain in rats by increasing fatty acid ocidation " . Abstracts.2004. European thyroid Association Annual Meeting. 10) Goglia et al. FEBS Letters. 452, 115-120 (1999) 11) Lombardi et al. Biochem J. 330, 521-526 (1998). 12) Lombardi et al. Endocrinology. 141, 1729-1734 (2000) 13) Ball et al. J Molec Endocrinology. 19, 137-147 (1997). 14)Assunta Lombardi, Antonia Lanni, Pieter de Lange, Elena Silvestri, Paola Grasso, lba Senese, Goglia and Moreno. " Acute administration of 3,5-diiodo-l-thyronine to hypothyroid rats affects bioenergetic parameters in rat skeletal muscle mitochondria " .FEBS Letters, Volume 581, Issue 30, 22 December 2007, Pages 5911-5916 14) J. Kvetny. Horm. Metab. Res. 24:322-325, 1992. 16) Moreno M, et al. " Effect of 3, 5-Diiodo-L-thyronine on thyroid stimulating hormone and growth hormone serum levels in hypothyroid rats. " Life Sciences, Volume 62, No.26, pp. 2369-2377, 1998. 17) Horst C, et al. " 3, 5-Di-iodo-L-thyronine suppresses TSH in rats in vivo and in rat pituitary fragments in vitro. " J Endocrinol 1995 May;145(2):291-7 Quote Link to comment Share on other sites More sharing options...
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