Re: MRSA +IODINE. WAS: heart palpitations. Was: For Venizia

[Guest guest]

Betadine is povidone-iodine.

Povidine-iodine is iodine with polyvinyl pyrrolidone (water-soluble

polymer used as a suspension). Here's the wiki def from USP:

http://en.wikipedia.org/wiki/Povidone-iodine

Sam

>

> I recently asked about whether iodine would kill a culture of

MRSA. The

> way I'm reading the results below is that Hibiclens, Acute-Kare and

> Phisohex all failed to kill ALL of the MRSA. However, Betadine

> [Providence-iodine] at 1 to 100 dilution kills ALL of the MRSA in a

> culture. Is that how you guys interpret it?

>

> So how does Betadine [Providence-iodine] differ from plain old

iodine?

>

>

> .

> .

>

>

> <http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=271835>

> > Abstract

> > Various commonly used antiseptics were tested against three

strains of

> > methicillin-resistant Staphylococcus aureus (MRSA) at stock

strength

> > and in serial 10-fold dilutions. The stock solutions of 4%

> > chlorhexidine gluconate-alcohol (Hibiclens), 1% p-chloro-m-

xylenol

> > (Acute-Kare), and 3% hexachlorophene (Phisohex) produced 2-log

> > reductions of MRSA after a 15-s exposure, but even after 240 s,

these

> > solutions failed to kill all the MRSA. Povidone-iodine (Betadine)

> > solution was maximally effective at the 1:100 dilution, killing

all

> > the MRSA within 15 s; other dilutions were less effective, though

each

> > killed the MRSA within 120 s. Similar results were obtained with

three

> > different strains of methicillin-susceptible S. aureus. Thus, of

the

> > four most commonly used antiseptics, povidone-iodine, when

diluted

> > 1:100, was the most rapidly bactericidal against both MRSA and

> > methicillin-susceptible S. aureus.

>

[Guest guest]

-

That study was in 1985. The strain of MRSA back then is NOT the same strain

that we have today. What we have today is a SUPERBUG that is resistant.

You can NOT compare the two strains. Not even close. That is the point.

The other sub point is that what can be killed in a culture is NOT

representative of what is happening in the human body with a massive

infection process that is occurring.

Plus. Betadine is NOT pure iodine.

Nancie

-- MRSA +IODINE. WAS: heart palpitations. Was: For

Venizia

I recently asked about whether iodine would kill a culture of MRSA. The

way I'm reading the results below is that Hibiclens, Acute-Kare and

Phisohex all failed to kill ALL of the MRSA. However, Betadine

[Providence-iodine] at 1 to 100 dilution kills ALL of the MRSA in a

culture. Is that how you guys interpret it?

So how does Betadine [Providence-iodine] differ from plain old iodine?

..

..

<http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=271835>

> Abstract

> Various commonly used antiseptics were tested against three strains of

> methicillin-resistant Staphylococcus aureus (MRSA) at stock strength

> and in serial 10-fold dilutions. The stock solutions of 4%

> chlorhexidine gluconate-alcohol (Hibiclens), 1% p-chloro-m-xylenol

> (Acute-Kare), and 3% hexachlorophene (Phisohex) produced 2-log

> reductions of MRSA after a 15-s exposure, but even after 240 s, these

> solutions failed to kill all the MRSA. Povidone-iodine (Betadine)

> solution was maximally effective at the 1:100 dilution, killing all

> the MRSA within 15 s; other dilutions were less effective, though each

> killed the MRSA within 120 s. Similar results were obtained with three

> different strains of methicillin-susceptible S. aureus. Thus, of the

> four most commonly used antiseptics, povidone-iodine, when diluted

> 1:100, was the most rapidly bactericidal against both MRSA and

> methicillin-susceptible S. aureus.

[Guest guest]

Hi, Sam. I just recently noticed the article I quoted is over 20 years

old, so I don't know how relevant it would be for today's MRSA. Anyway,

it appears that the active ingredient in Betadine is iodine, while the

other ingredient are just a suspension agent; is that right?

Thanks for the link,

>

> Posted by: " Sam " k9gang@...

>

<mailto:k9gang@...?Subject=%20Re%3A%20MRSA%20%2BIODINE%2E%20%20WAS%3A\

%20heart%20palpitations%2E%20%20Was%3A%20%20For%20Venizia>

> stealthwind <stealthwind>

>

>

> Thu Sep 11, 2008 8:57 pm (PDT)

>

> Betadine is povidone-iodine.

> Povidine-iodine is iodine with polyvinyl pyrrolidone (water-soluble

> polymer used as a suspension). Here's the wiki def from USP:

> http://en.wikipedia.org/wiki/Povidone-iodine

> <http://en.wikipedia.org/wiki/Povidone-iodine>

>

> Sam

>

>

> >

> > I recently asked about whether iodine would kill a culture of

> MRSA. The

> > way I'm reading the results below is that Hibiclens, Acute-Kare and

> > Phisohex all failed to kill ALL of the MRSA. However, Betadine

> > [Providence-iodine] at 1 to 100 dilution kills ALL of the MRSA in a

> > culture. Is that how you guys interpret it?

> >

> > So how does Betadine [Providence-iodine] differ from plain old

> iodine?

> >

> >

[Guest guest]

When I posted the question I did not realize that it was over 20 years

old. So I didn't realize that MRSA couldn't possibly be the same as

today's mutated version.

I'm still surprised that a culture of MRSA would [or might] not be

killed by iodine; but you have to realize I AM NOT a medical

professional or a scientist. I believe I do have somewhat an ability to

discern bs from credible information in a lot of cases; but I will

always have to rely upon the experts.

Thanks,

>

> Posted by: " Nancie Barnett " deifspirit@...

>

<mailto:deifspirit@...?Subject=%20Re%3A%20MRSA%20%2BIODINE%2E%20%20WAS%3A%20\

heart%20palpitations%2E%20%20Was%3A%20%20For%20Venizia>

> aspenfairy1 <aspenfairy1>

>

>

> Thu Sep 11, 2008 9:20 pm (PDT)

>

> -

> That study was in 1985. The strain of MRSA back then is NOT the same

> strain

> that we have today. What we have today is a SUPERBUG that is resistant.

> You can NOT compare the two strains. Not even close. That is the point.

> The other sub point is that what can be killed in a culture is NOT

> representative of what is happening in the human body with a massive

> infection process that is occurring.

> Plus. Betadine is NOT pure iodine.

> Nancie

>

> -- MRSA +IODINE. WAS: heart palpitations. Was: For

> Venizia

>

> I recently asked about whether iodine would kill a culture of MRSA. The

> way I'm reading the results below is that Hibiclens, Acute-Kare and

> Phisohex all failed to kill ALL of the MRSA. However, Betadine

> [Providence-iodine] at 1 to 100 dilution kills ALL of the MRSA in a

> culture. Is that how you guys interpret it?

>

> So how does Betadine [Providence-iodine] differ from plain old iodine?

>

>

[Guest guest]

Nancie,

You wrote:

> That study was in 1985. The strain of MRSA back then is NOT the same

> strain that we have today. What we have today is a SUPERBUG that

> is resistant....

MRSA is resistant to antibiotics, not antiseptics. Povidone iodine is still

effective against it, when used for topical antisepsis. It won't stop an

infection already in place. Here is a review paper hot off the presses

confirming this:

Piyush Durani, Leaper " Povidone–iodine: use in hand disinfection, skin

preparation and antiseptic irrigation, " International Wound Journal

Volume 5 Issue 3, Pages 376 - 387, 28 Jun 2008.

Abstract:

Iodine and its antibacterial properties have been used for the prevention or

management of wound infections for over 150 years. However, the use of solutions

(tincture) of iodine has been replaced by the widespread use of

povidone–iodine, a water-soluble compound, which is a combination of molecular

iodine and polyvinylpyrrolidone. The resultant broad spectrum of antimicrobial

activity is well documented and its efficacy, particularly in relation to

resistant micro-organisms such as methicillin-resistant Staphylococcus aureus,

has been shown. In the clinical environment, there is no general agreement

regarding the 'best' antiseptic and the practice varies widely. This article

reviews the studies that have assessed the efficacy of povidone–iodine in hand

disinfection and skin preparation and its use as an antiseptic irrigant. ...

Chuck