TSH reference ranges

[Guest guest]

Nancie,

You wrote:

>

> excuse me but my MD told me that she is an expert in thyroid diseases

> and she uses armour! she- prudence Hall told me that the new upper limit

> is now back to 5.0 for the TSH....

I have not seen any new papers suggesting an increase in the TSH limit,

just more data confirming the drop to 3.0 (or lower for T3 meds),

although the labs seem to continue to report the older limits. You might

want to ask her about those recommendations of the American Society of

Endocrinologists and the National Academy of Clinical Biochemists from

2003. It is obvious their conclusions are contrary to those of the

American Thyroid Association.

http://www.nacb.org/lmpg/thyroid_lmpg_pub.stm

http://thyroid.about.com/gi/dynamic/offsite.htm?zi=1/XJ & sdn=thyroid & zu=http%3A%2\

F%2Fwww.nacb.org%2Flmpg%2Fthyroid_LMPG_PDF.stm

With the associated research references:

http://www.altsupportthyroid.org/tsh/tshmedrefs4.php#supp

http://www.thyroid-info.com/articles/osteoporosis.htm

Chuck

[Guest guest]

chuck-

just am fyi ; those links are dead.

TSH reference ranges

American Thyroid Association.

http://www.nacb.org/lmpg/thyroid_lmpg_pub.stm<http://www.nacb.org/lmpg/thyroid_l\

mpg_pub.stm>

http://thyroid.about.com/gi/dynamic/offsite.htm?zi=1/XJ & sdn=thyroid & zu=http%3A%2\

F%2Fwww.nacb.org%2Flmpg%2Fthyroid_LMPG_PDF.stm<http://thyroid.about.com/gi/dynam\

ic/offsite.htm?zi=1/XJ & sdn=thyroid & zu=http%3A%2F%2Fwww.nacb.org%2Flmpg%2Fthyroid\

_LMPG_PDF.stm>

MARKETPLACE

------------------------------------------------------------------------------

Earn your degree in as few as 2 years - Advance your career with an AS, BS, MS

degree<http://us.ard./SIG=12p9av0dv/M=571476.12066680.12490312.11509771\

/D=grphealth/S=1709251082:MKP1/Y=/EXP=1199853812/A=5086951/R=0/SIG=12k8pu1n\

3/*http://college-finder.net/index.cfm?key=_colfngrouptxt_12066680 & c=CA1529\

32587> - College-Finder.net.

<;_ylc=X3oDMTJjN3Q5Z2drBF9TAzk3MzU5NzE0BGdycElkAzE0NTY2N\

ARncnBzcElkAzE3MDkyNTEwODIEc2VjA2Z0cgRzbGsDZ2ZwBHN0aW1lAzExOTk4NDY2MTI->

Change settings via the

Web<hypothyroidism/join;_ylc=X3oDMTJlNDhrcmhmBF9TA\

zk3MzU5NzE0BGdycElkAzE0NTY2NARncnBzcElkAzE3MDkyNTEwODIEc2VjA2Z0cgRzbGsDc3RuZ3MEc\

3RpbWUDMTE5OTg0NjYxMg--> ( ID required)

Change settings via email: Switch delivery to Daily

Digest<mailto:hypothyroidism-digest ?subject=Email Delivery:

Digest> | Switch format to

Traditional<mailto:hypothyroidism-traditional ?subject=Change

Delivery Format: Traditional>

Visit Your Group

<hypothyroidism;_ylc=X3oDMTJjdWZrcDFtBF9TAzk3MzU5N\

zE0BGdycElkAzE0NTY2NARncnBzcElkAzE3MDkyNTEwODIEc2VjA2Z0cgRzbGsDaHBmBHN0aW1lAzExO\

Tk4NDY2MTI->| Terms of Use <>|

Unsubscribe <mailto:hypothyroidism-unsubscribe ?subject=>Recent

Activity

a.. 15New

Members<hypothyroidism/members;_ylc=X3oDMTJlcWdsdT\

drBF9TAzk3MzU5NzE0BGdycElkAzE0NTY2NARncnBzcElkAzE3MDkyNTEwODIEc2VjA3Z0bARzbGsDdm\

1icnMEc3RpbWUDMTE5OTg0NjYxMg-->

Visit Your Group

<hypothyroidism;_ylc=X3oDMTJkNnI3b29kBF9TAzk3MzU5N\

zE0BGdycElkAzE0NTY2NARncnBzcElkAzE3MDkyNTEwODIEc2VjA3Z0bARzbGsDdmdocARzdGltZQMxM\

Tk5ODQ2NjEy>

Get cancer

support<http://us.ard./SIG=12ng879dh/M=493064.12016247.12445656.1047826\

5/D=grphealth/S=1709251082:NC/Y=/EXP=1199853812/A=4617369/R=0/SIG=11uofhk5p\

/*http://advision.webevents./cancersupport/index.html>

Connect w/ others

find help & share

Healthy Eating

Zone<http://us.ard./SIG=12mbnak1g/M=493064.12016231.124456479706571/D=g\

rphealth/S=1709251082:NC/Y=/EXP=1199853812/A=4718982/R=0/SIG=11kunoe70/*htt\

p://advision.webevents./healthyeating/>

Encouraging families

to eat healthy.

Health

Looking for

Love?<http://us.ard./SIG=12ma2taof/M=493064.12016303.12445695.9706571/D\

=grphealth/S=1709251082:NC/Y=/EXP=1199853812/A=5008808/R=0/SIG=10q26t77l/*h\

ttp://health./>

Find relationship

advice and answers.

.

[Guest guest]

Nancie,

You wrote:

>

> just am fyi ; those links are dead.

OOPS! Thanks. They must have taken them down recently. I'll have to take

those out of the FAQ, also. Must be the brain fog.

Here is an article citing them:

http://thyroid.about.com/cs/testsforthyroid/a/newrange.htm

The original documents:

Demers, ce M.; Carole A. Spencer (2002). LMPG: Laboratory Support

for the Diagnosis and Monitoring of Thyroid Disease. National Academy of

Clinical Biochemistry (USA). Section 2.: Pre-analytic factors;

Section 3.C.: Thyrotropin/ Thyroid Stimulating Hormone (TSH) measurement

AACE Medical Guidelines for Clinical Practice for the Evaluation and

Treatment of Hyperthyroidism and Hypothyroidism, Endocrine Practice,

Vol. 8, No. 6, Nov/Dec 2002.

Sources: Fatourechi V, Klee GG, Grebe SK, et al. Effects of reducing the

upper limit of normal TSH values. JAMA. 2003;290:3195-3196.

http://www.clinchem.org/cgi/content/abstract/51/8/1480?maxtoshow= & HITS= & hits= & RE\

SULTFORMAT= & author1=Kratzsch & andorexactfulltext=and & searchid=1 & FIRSTINDEX=10 & res\

ourcetype=HWCIT

Some excerpts:

American Association of Clinical Endocrinologists: doctors should

" consider treatment for patients who test outside the boundaries of a

narrower margin based on a target TSH level of 0.3 to 3.0. "

National Academy of Clinical Biochemistry, part of the Academy of the

American Association for Clinical Chemistry (AACC), and presented in

their Laboratory Medicine Practice Guidelines for the Diagnosis and

Monitoring of Thyroid Disease: " It is likely that the current upper

limit of the population reference range is skewed by the inclusion of

persons with occult thyroid dysfunction. "

" In the future, it is likely that the upper limit of the serum TSH

euthyroid reference range will be reduced to 2.5 mIU/L because >95% of

rigorously screened normal euthyroid volunteers have serum TSH values

between 0.4 and 2.5 mIU/L. "

" A serum TSH result between 0.5 and 2.0 mIU/L is generally considered

the therapeutic target for a standard L-T4 replacement dose for primary

hypothyroidism. "

" Thyroxine requirements increase during pregnancy. Thyroid status should

be checked with TSH + FT4 during each trimester of pregnancy. The L-T4

dose should be increased (usually by 50 micrograms/day) to maintain a

serum TSH between 0.5 and 2.0 mIU/L and a serum FT4 in the upper third

of the normal reference interval. "

Curiously my TSH today reached 5.27! My doctor is going to look at the

frees and total T4 before he ups my T4 and gives me some T3. I feel

fine, though.

Chuck