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http://www.cnn.com/2007/TECH/science/10/22/body.burden/index.html

Tests reveal high chemical levels in kids' bodies

By Jordana

CNN

NEW YORK (CNN) -- Hammond and Holland were intrigued

when a friend at the Oakland Tribune asked them and their two young children to

take part in a cutting-edge study to measure the industrial chemicals in their

bodies.

" In the beginning, I wasn't worried at all; I was fascinated, " Hammond,

37, recalled.

But that fascination soon changed to fear, as tests revealed that their

children -- Rowan, then 18 months, and Mikaela, then 5 -- had chemical exposure

levels up to seven times those of their parents.

" [Rowan's] been on this planet for 18 months, and he's loaded with a

chemical I've never heard of, " Holland, 37, said. " He had two to three times the

level of flame retardants in his body that's been known to cause thyroid

dysfunction in lab rats. "

The technology to test for these flame retardants -- known as

polybrominated diphenyl ethers (PBDEs) -- and other industrial chemicals is less

than 10 years old. Environmentalists call it " body burden " testing, an allusion

to the chemical " burden, " or legacy of toxins, running through our bloodstream.

Scientists refer to this testing as " biomonitoring. "

Most Americans haven't heard of body burden testing, but it's a hot topic

among environmentalists and public health experts who warn that the industrial

chemicals we come into contact with every day are accumulating in our bodies and

endangering our health in ways we have yet to understand. See which household

products contain industrial chemicals »

" We are the humans in a dangerous and unnatural experiment in the United

States, and I think it's unconscionable, " said Dr. Leo Trasande, assistant

director of the Center for Children's Health and the Environment at the Mount

Sinai Medical Center in New York City. Watch get his blood drawn

for testing »

Dr. Trasande says that industrial toxins could be leading to more

childhood disease and disorders.

" We are in an epidemic of environmentally mediated disease among American

children today, " he said. " Rates of asthma, childhood cancers, birth defects and

developmental disorders have exponentially increased, and it can't be explained

by changes in the human genome. So what has changed? All the chemicals we're

being exposed to. "

Whelan, president of the American Council on Science and Health,

a public health advocacy group, disagrees.

" My concern about this trend about measuring chemicals in the blood is

it's leading people to believe that the mere ability to detect chemicals is the

same as proving a hazard, that if you have this chemical, you are at risk of a

disease, and that is false, " she said. Whelan contends that trace levels of

industrial chemicals in our bodies do not necessarily pose health risks.

In 2004, the Hollands became the first intact nuclear family in the United

States to undergo body burden testing. Rowan, at just 1½ years old, became the

youngest child in the U.S. to be tested for chemical exposure with this method.

Rowan's extraordinarily high levels of PBDEs frightened his parents and

left them with a looming question: If PBDEs are causing neurological damage to

lab rats, could they be doing the same thing to Rowan? The answer is that no one

knows for sure. In the three years since he was tested, no developmental

problems have been found in Rowan's neurological system.

Dr. Trasande said children up to six years old are most at risk because

their vital organs and immune system are still developing and because they

depend more heavily on their environments than adults do.

" Pound for pound, they eat more food, they drink more water, they breathe

in more air, " he said. " And so [children] carry a higher body burden than we

do. "

Studies on the health effects of PBDEs are only just beginning, but many

countries have heeded the warning signs they see in animal studies. Sweden

banned PBDEs in 1998. The European Union banned most PBDEs in 2004. In the

United States, the sole manufacturer of two kinds of PBDEs voluntarily stopped

making them in 2004. A third kind, Deca, is still used in the U.S. in electrical

equipment, construction material, mattresses and textiles.

Another class of chemicals that showed up in high levels in the Holland

children is known as phthalates. These are plasticizers, the softening agents

found in many plastic bottles, kitchenware, toys, medical devices, personal care

products and cosmetics. In lab animals, phthalates have been associated with

reproductive defects, obesity and early puberty. But like PBDEs, little is known

about what they do to humans and specifically children.

Russ Hauser, an associate professor of environmental and occupational

epidemiology at the Harvard School of Public Health, has done some of the few

human studies on low-level phthalate exposure. His preliminary research shows

that phthalates may contribute to infertility in men. A study led by Shanna Swan

of the University of Rochester in New York shows that prenatal exposure to

phthalates in males may be associated with impaired testicular function and with

a defect that shortens the space between the genitals and anus.

The Environmental Protection Agency does not require chemical

manufacturers to conduct human toxicity studies before approving their chemicals

for use in the market. A manufacturer simply has to submit paperwork on a

chemical, all the data that exists on that chemical to date, and wait 90 days

for approval.

Wood, an EPA spokeswoman, insists the agency has the tools to

ensure safe oversight.

" If during the new-chemical review process, EPA determines that it may

have concerns regarding risk or exposure, the EPA has the authority to require

additional testing, " she said. EPA records show that of the 1,500 new chemicals

submitted each year, the agency asks for additional testing roughly 10 percent

of the time. The EPA has set up a voluntary testing program with the major

chemical manufacturers to retroactively test some of the 3,000 most widely used

chemicals.

Dr. Trasande believes that is too little, too late.

" The problem with these tests is that they are really baseline tests that

don't measure for the kind of subtle health problems that we're seeing, " Dr.

Trasande said.

In the three years since her family went through body burden testing,

Hammond has become an activist on the issue. She's testified twice in

the California legislature to support a statewide body burden testing program, a

bill that passed last year. also speaks to various public health groups

about her experience, taking Mikaela, now 8, and Rowan, now 5, with her. So far,

her children show no health problems associated with the industrial chemicals in

their bodies.

" I'm angry at my government for failing to regulate chemicals that are in

mass production and in consumer products. " Hammond says. " I don't think it

should have to be up to me to worry about what's in my couch. "

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10:35 AM

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