Re: LDN, MS, Lyme, and Minocycline

February 27, 2004

Make sure minocycline is taken with Vit C or you will ruin your teeth.I take minocycline with LDN and there's no problem. It is an antibiotic for acne but I saw it work a miracle for my friend's Scleroderma so thought I would try. There is a trial being done in Canada on this for MS.

It may make you dizzy in the AM so be careful for a few days. All I have noticed is that it has given me great gums.(no kidding, my dentist was shocked) i now take it 3X aweek, 100mg. This is the Rhematoid arthritis protocol. Not sure if it has done anything for my MS but I do feel immediate relief of muscle /back pain if I have overworked at gym. Keep us posted on what you find. Kiki

February 27, 2004

If you are having a Herxheimer reaction it is my understanding that it

usually occurs between day 4 and day 16 after beginning the antibiotic. Can

you ride it out and see if it improves? I don't know of any other way to

tell if that is what is going on.

I've experienced a very similar occurrence nearly every time I've had to use

antibiotics, so I really try to avoid them, plus it takes me so long to get

my insides back in balance.

While on the antibiotic you are also killing the beneficial bacteria, have

you considered adding a really good probiotic to help maintain your

intestinal flora??

Keep us posted,

----- Original Message -----

From: " scott_627 " <kuriouskat@...>

Sent: Thursday, February 26, 2004 7:35 PM

Subject: [low dose naltrexone] LDN, MS, Lyme, and Minocycline

> Well, that's a mouthful of a subject, isn't it? I raise a few

> issues here, so hang on.

>

> I've had 2 neurological attacks in 2 years, but as of my last MRI,

> no lesions. So clinically, I don't have MS, which means my neuro

> hasn't asked me to take a CRAB (or anything else) yet. But we are

> both assuming it's a waiting game until lesions show up, as I've

> been tested for everything else under the sun with negative results.

>

> Not wanting to wait while I got worse, I had my internist prescribe

> LDN for me in December. Since starting it, my symptoms (sensory,

> fatigue, weakness) have mostly been getting better. 2 weeks ago, I

> had a " mini-attack " for about 2 days, as I wrote about in

> the " Relapse while on LDN " thread. In an effort to be more

> aggressive in slowing down the presumed MS, I asked my internist to

> prescribe minocycline. Minocycline is a common antibiotic, but it's

> being tested as a therapy for MS. Note that it's not the antibiotic

> effect that works with MS, but the anti-inflammatory effect. I've

> been in contact with 2 RR patients who have had good results with

> minocycline. I'll post links at the end of this for those who want

> more info on this.

>

> So as of last Saturday, I was taking my 4.5mg LDN nightly, and I

> started 100mg minocycline twice a day. The first couple of days

> were fine, but Tuesday I felt like I'd been run over by a truck--

> fatigued, weak, with a flare up of my symptoms. This leads me to

> several questions.

>

> 1. Is anyone aware of any reason why LDN should not be taken with

> an antibiotic? I didn't see anything on the ldn web site one way or

> another.

>

> 2. One of my doctors several months ago proposed that, even though

> I tested negative for Lyme, I should take a trial of tetracycline

> (almost the same as minocycline). His theory was that if I had Lyme

> bacteria, I would feel worse as the Lyme bacteria died. I didn't

> try it then, but I appear to be living his prediction now--I think

> it's called the Jarisch-Herxheimer reaction (although mine is mild,

> I think). So maybe I have Lyme, not MS? Has anyone experienced

> anything like this? Or I'm just having an MS flare-up? Or ???

>

> 3. Can anyone see any reason not to take LDN with minocycline when

> it's acting as a " neuroprotective agent " (see links below)? This is

> probably a question for Dr. Bihari, if anyone can pass it along to

> him.

>

> Wow, that's a lot! Thanks for any thoughts or random speculation!

>

> Here are the links on the prospects of minocycline as disease-

> modifying therapy for MS:

>

> http://tinylink.com/?MdYn9bcmoQ

>

> http://tinylink.com/?HJaBhZ3iak

>

> Thanks again!

>

February 27, 2004

, did you get a western blot lyme disease test. Last I researched it that

was the most accurate and have you been tested for Syndrome which mimics

ms. If you are taking the antibiotic for antiinflamatory effects, why not try

turmeric. I haven`t read the articles you mentioned but agree with . You

are throwing your intestinal flora out of balance and need a strong probiotic. I

use primal defense by Garden of Life. It is good for sinus problems headaches,

constipation,etc. Check it out and be glad there are no lesions. There are so

many options available for people with chronic conditions. I like to call it a

condition because conditions are ever changing. I beleive in my heart those of

us who walk our own path will win this challenge called ms. Hope and Prayers,

Kathy

-----Original Message-----

From: <jatrac1@...>

Sent: Feb 26, 2004 11:03 PM

low dose naltrexone

Subject: Re: [low dose naltrexone] LDN, MS, Lyme, and Minocycline