Re: STABILITY OF NALTREXONE

[Guest guest]

This is excellent, Larry

what edition..is it recent text, as my compunding supplies' specialists would only stand by 14 days in a fridge, in their diluent..1% xanthan in water!

Information like this is a great help to compounders and patients, as the liquid formulation is a good bit cheaper, plus its useful in people with swallowing difficulties.

n (Compounder and campaigner).. Ireland

----- Original Message -----

From: Larry J. Frieders

low dose naltrexone

Sent: Wednesday, March 03, 2004 10:44 PM

Subject: [low dose naltrexone] STABILITY OF NALTREXONE

NOT 1 day... NOT 1 week...BUT a MONTH or MORE!

Naltrexone is quite stable in water.

I am quoting from Trissel's book, "Stability of Compounded Formulations", Second Edition, page 266

"Stability-indicating HPLC analysis found less than 10% loss within 90 days at either 4 degrees C or 25 degrees C; most samples exhibited no loss. .... The recommended shelf lives of 30 and 60 days stored at 25 degrees C and 4 degrees C, respectively."

This is a reference book that every compounder OUGHT to have on hand.

4 degrees C is refrigeration and 25 degrees C is room temperature.

We make a lot of naltrexone solutions for people who need to adjust their doses. The most popular strength is 1mg per ml. We supply a syringe with which the patient can measure the correct dose. It is bitter so it needs to be mixed with something (unless you have strong taste buds). Nobody has ever complained that it "stopped working".

Larry J. Frieders,RPh |The Compounder575 W. Illinois Ave ~ Aurora, IL 60506 630-859-0333 FAX 630-859-0114 Sample newsletter http://www.theCompounder.com/NL-Sample.html

Any health related information on our web pages or in our newsletters is for educational purposes only. None of the information we provide is to be construed as medical advice. Before applying any therapy or use of herbs, you may want to seek advice from your health care professional. Our information should not be a substitute for physician evaluation or treatment by a health care professional and is not intended to provide or confirm a diagnosis.

----- Original Message -----

From: Lynda Phelps

low dose naltrexone

Sent: Wednesday, March 03, 2004 6:33 AM

Subject: Re: [low dose naltrexone] Re: LDN

Naltrexone is good for about a week, I was told by a pharmacist. That iswhy I only dilute half a tablet (25 mg) at a time which gives me five daysworth of 4.5 mg. It works fine for me.HI LYNDA-I GET THE TABLET - BUT READ EARLIER ON THIS SITE THATNALTREXONE IS NOT STABLE IN LIQUID FOR AN EXTENDED TIME.DOES ANYONE KNOW FOR SURE?BESTAUNT

[Guest guest]

Trissel's Stability of Compounded Formulations

Second Edition

Published in 2000

Larry J. Frieders,RPh |The Compounder575 W. Illinois Ave ~ Aurora, IL 60506 630-859-0333 FAX 630-859-0114 Sample newsletter http://www.theCompounder.com/NL-Sample.html

Any health related information on our web pages or in our newsletters is for educational purposes only. None of the information we provide is to be construed as medical advice. Before applying any therapy or use of herbs, you may want to seek advice from your health care professional. Our information should not be a substitute for physician evaluation or treatment by a health care professional and is not intended to provide or confirm a diagnosis.

----- Original Message -----

From: n Quinn

low dose naltrexone

Sent: Thursday, March 04, 2004 3:17 AM

Subject: Re: [low dose naltrexone] STABILITY OF NALTREXONE

This is excellent, Larry

what edition..is it recent text, as my compunding supplies' specialists would only stand by 14 days in a fridge, in their diluent..1% xanthan in water!

Information like this is a great help to compounders and patients, as the liquid formulation is a good bit cheaper, plus its useful in people with swallowing difficulties.

n (Compounder and campaigner).. Ireland

----- Original Message -----

From: Larry J. Frieders

low dose naltrexone

Sent: Wednesday, March 03, 2004 10:44 PM

Subject: [low dose naltrexone] STABILITY OF NALTREXONE

NOT 1 day... NOT 1 week...BUT a MONTH or MORE!

Naltrexone is quite stable in water.

I am quoting from Trissel's book, "Stability of Compounded Formulations", Second Edition, page 266

"Stability-indicating HPLC analysis found less than 10% loss within 90 days at either 4 degrees C or 25 degrees C; most samples exhibited no loss. .... The recommended shelf lives of 30 and 60 days stored at 25 degrees C and 4 degrees C, respectively."

This is a reference book that every compounder OUGHT to have on hand.

4 degrees C is refrigeration and 25 degrees C is room temperature.

We make a lot of naltrexone solutions for people who need to adjust their doses. The most popular strength is 1mg per ml. We supply a syringe with which the patient can measure the correct dose. It is bitter so it needs to be mixed with something (unless you have strong taste buds). Nobody has ever complained that it "stopped working".

Larry J. Frieders,RPh |The Compounder575 W. Illinois Ave ~ Aurora, IL 60506 630-859-0333 FAX 630-859-0114 Sample newsletter http://www.theCompounder.com/NL-Sample.html

Any health related information on our web pages or in our newsletters is for educational purposes only. None of the information we provide is to be construed as medical advice. Before applying any therapy or use of herbs, you may want to seek advice from your health care professional. Our information should not be a substitute for physician evaluation or treatment by a health care professional and is not intended to provide or confirm a diagnosis.

----- Original Message -----

From: Lynda Phelps

low dose naltrexone

Sent: Wednesday, March 03, 2004 6:33 AM

Subject: Re: [low dose naltrexone] Re: LDN

Naltrexone is good for about a week, I was told by a pharmacist. That iswhy I only dilute half a tablet (25 mg) at a time which gives me five daysworth of 4.5 mg. It works fine for me.HI LYNDA-I GET THE TABLET - BUT READ EARLIER ON THIS SITE THATNALTREXONE IS NOT STABLE IN LIQUID FOR AN EXTENDED TIME.DOES ANYONE KNOW FOR SURE?BESTAUNT

[Guest guest]

Larry,

I used to use Methylcellolose in formulating mouth-ulcer "dressings". It still dissolves very quickly, so would not affect dissolution of Naltx in the gut..?

Also I note the stability data, but would have concerns about contamination from opning/closing the bottle every day, and would still put a short life on a bottle of (preservative free) natrexone in water)

n

----- Original Message -----

From: Larry J. Frieders

low dose naltrexone

Sent: Thursday, March 04, 2004 3:00 PM

Subject: Re: [low dose naltrexone] STABILITY OF NALTREXONE

Trissel's Stability of Compounded Formulations

Second Edition

Published in 2000

Larry J. Frieders,RPh |The Compounder575 W. Illinois Ave ~ Aurora, IL 60506 630-859-0333 FAX 630-859-0114 Sample newsletter http://www.theCompounder.com/NL-Sample.html

Any health related information on our web pages or in our newsletters is for educational purposes only. None of the information we provide is to be construed as medical advice. Before applying any therapy or use of herbs, you may want to seek advice from your health care professional. Our information should not be a substitute for physician evaluation or treatment by a health care professional and is not intended to provide or confirm a diagnosis.

----- Original Message -----

From: n Quinn

low dose naltrexone

Sent: Thursday, March 04, 2004 3:17 AM

Subject: Re: [low dose naltrexone] STABILITY OF NALTREXONE

This is excellent, Larry

what edition..is it recent text, as my compunding supplies' specialists would only stand by 14 days in a fridge, in their diluent..1% xanthan in water!

Information like this is a great help to compounders and patients, as the liquid formulation is a good bit cheaper, plus its useful in people with swallowing difficulties.

n (Compounder and campaigner).. Ireland

----- Original Message -----

From: Larry J. Frieders

low dose naltrexone

Sent: Wednesday, March 03, 2004 10:44 PM

Subject: [low dose naltrexone] STABILITY OF NALTREXONE

NOT 1 day... NOT 1 week...BUT a MONTH or MORE!

Naltrexone is quite stable in water.

I am quoting from Trissel's book, "Stability of Compounded Formulations", Second Edition, page 266

"Stability-indicating HPLC analysis found less than 10% loss within 90 days at either 4 degrees C or 25 degrees C; most samples exhibited no loss. .... The recommended shelf lives of 30 and 60 days stored at 25 degrees C and 4 degrees C, respectively."

This is a reference book that every compounder OUGHT to have on hand.

4 degrees C is refrigeration and 25 degrees C is room temperature.

We make a lot of naltrexone solutions for people who need to adjust their doses. The most popular strength is 1mg per ml. We supply a syringe with which the patient can measure the correct dose. It is bitter so it needs to be mixed with something (unless you have strong taste buds). Nobody has ever complained that it "stopped working".

Larry J. Frieders,RPh |The Compounder575 W. Illinois Ave ~ Aurora, IL 60506 630-859-0333 FAX 630-859-0114 Sample newsletter http://www.theCompounder.com/NL-Sample.html

Any health related information on our web pages or in our newsletters is for educational purposes only. None of the information we provide is to be construed as medical advice. Before applying any therapy or use of herbs, you may want to seek advice from your health care professional. Our information should not be a substitute for physician evaluation or treatment by a health care professional and is not intended to provide or confirm a diagnosis.

----- Original Message -----

From: Lynda Phelps

low dose naltrexone

Sent: Wednesday, March 03, 2004 6:33 AM

Subject: Re: [low dose naltrexone] Re: LDN

Naltrexone is good for about a week, I was told by a pharmacist. That iswhy I only dilute half a tablet (25 mg) at a time which gives me five daysworth of 4.5 mg. It works fine for me.HI LYNDA-I GET THE TABLET - BUT READ EARLIER ON THIS SITE THATNALTREXONE IS NOT STABLE IN LIQUID FOR AN EXTENDED TIME.DOES ANYONE KNOW FOR SURE?BESTAUNT

[Guest guest]

Methylcellulose is the standard for retarding dissolution in the gut. I didn't make it up , but I've been following that recommendation for years - and it seems to work, especially when we make the slow release T3.

When we dispense liquids - especially in aqueous bases - we supply a special cap and syringe. We usually keep the dating around 30 days and I've not heard of a contamination issue from any patients (bottle is kept in refrigerator). I agree that fungal contamination is possible, but how does it play out in reality? I would never leave a bottle for 30 days in a dirty environment like a hospital, but most homes are clean enough to avoid contamination over a 30 day period. Also note that xanthan gum in suspension is more likely to "go bad". I have often seen that stuff grow mold.

Larry J. Frieders,RPh |The Compounder575 W. Illinois Ave ~ Aurora, IL 60506 630-859-0333 FAX 630-859-0114 Sample newsletter http://www.theCompounder.com/NL-Sample.html

Any health related information on our web pages or in our newsletters is for educational purposes only. None of the information we provide is to be construed as medical advice. Before applying any therapy or use of herbs, you may want to seek advice from your health care professional. Our information should not be a substitute for physician evaluation or treatment by a health care professional and is not intended to provide or confirm a diagnosis.

----- Original Message -----

From: n Quinn

low dose naltrexone

Sent: Friday, March 05, 2004 11:29 AM

Subject: Re: [low dose naltrexone] STABILITY OF NALTREXONE

Larry,

I used to use Methylcellolose in formulating mouth-ulcer "dressings". It still dissolves very quickly, so would not affect dissolution of Naltx in the gut..?

Also I note the stability data, but would have concerns about contamination from opning/closing the bottle every day, and would still put a short life on a bottle of (preservative free) natrexone in water)

n

----- Original Message -----

From: Larry J. Frieders

low dose naltrexone

Sent: Thursday, March 04, 2004 3:00 PM

Subject: Re: [low dose naltrexone] STABILITY OF NALTREXONE

Trissel's Stability of Compounded Formulations

Second Edition

Published in 2000

Larry J. Frieders,RPh |The Compounder575 W. Illinois Ave ~ Aurora, IL 60506 630-859-0333 FAX 630-859-0114 Sample newsletter http://www.theCompounder.com/NL-Sample.html

Any health related information on our web pages or in our newsletters is for educational purposes only. None of the information we provide is to be construed as medical advice. Before applying any therapy or use of herbs, you may want to seek advice from your health care professional. Our information should not be a substitute for physician evaluation or treatment by a health care professional and is not intended to provide or confirm a diagnosis.

----- Original Message -----

From: n Quinn

low dose naltrexone

Sent: Thursday, March 04, 2004 3:17 AM

Subject: Re: [low dose naltrexone] STABILITY OF NALTREXONE

This is excellent, Larry

what edition..is it recent text, as my compunding supplies' specialists would only stand by 14 days in a fridge, in their diluent..1% xanthan in water!

Information like this is a great help to compounders and patients, as the liquid formulation is a good bit cheaper, plus its useful in people with swallowing difficulties.

n (Compounder and campaigner).. Ireland

----- Original Message -----

From: Larry J. Frieders

low dose naltrexone

Sent: Wednesday, March 03, 2004 10:44 PM

Subject: [low dose naltrexone] STABILITY OF NALTREXONE

NOT 1 day... NOT 1 week...BUT a MONTH or MORE!

Naltrexone is quite stable in water.

I am quoting from Trissel's book, "Stability of Compounded Formulations", Second Edition, page 266

"Stability-indicating HPLC analysis found less than 10% loss within 90 days at either 4 degrees C or 25 degrees C; most samples exhibited no loss. .... The recommended shelf lives of 30 and 60 days stored at 25 degrees C and 4 degrees C, respectively."

This is a reference book that every compounder OUGHT to have on hand.

4 degrees C is refrigeration and 25 degrees C is room temperature.

We make a lot of naltrexone solutions for people who need to adjust their doses. The most popular strength is 1mg per ml. We supply a syringe with which the patient can measure the correct dose. It is bitter so it needs to be mixed with something (unless you have strong taste buds). Nobody has ever complained that it "stopped working".

Larry J. Frieders,RPh |The Compounder575 W. Illinois Ave ~ Aurora, IL 60506 630-859-0333 FAX 630-859-0114 Sample newsletter http://www.theCompounder.com/NL-Sample.html

Any health related information on our web pages or in our newsletters is for educational purposes only. None of the information we provide is to be construed as medical advice. Before applying any therapy or use of herbs, you may want to seek advice from your health care professional. Our information should not be a substitute for physician evaluation or treatment by a health care professional and is not intended to provide or confirm a diagnosis.

----- Original Message -----

From: Lynda Phelps

low dose naltrexone

Sent: Wednesday, March 03, 2004 6:33 AM

Subject: Re: [low dose naltrexone] Re: LDN

Naltrexone is good for about a week, I was told by a pharmacist. That iswhy I only dilute half a tablet (25 mg) at a time which gives me five daysworth of 4.5 mg. It works fine for me.HI LYNDA-I GET THE TABLET - BUT READ EARLIER ON THIS SITE THATNALTREXONE IS NOT STABLE IN LIQUID FOR AN EXTENDED TIME.DOES ANYONE KNOW FOR SURE?BESTAUNT

[Guest guest]

Could you answer a filler question for me? I asked my pharmacist

what she used as the filler and was told it was acidophilis. She

said it would be an immediate release mixture. Just wanted to

double check though.

Thank you.

> Methylcellulose is the standard for retarding dissolution in the

gut. I didn't make it up , but I've been following that

recommendation for years - and it seems to work, especially when we

make the slow release T3.

>

> When we dispense liquids - especially in aqueous bases - we supply

a special cap and syringe. We usually keep the dating around 30

days and I've not heard of a contamination issue from any patients

(bottle is kept in refrigerator). I agree that fungal contamination

is possible, but how does it play out in reality? I would never

leave a bottle for 30 days in a dirty environment like a hospital,

but most homes are clean enough to avoid contamination over a 30 day

period. Also note that xanthan gum in suspension is more likely

to " go bad " . I have often seen that stuff grow mold.

>

> Larry J. Frieders,RPh |The Compounder

> 575 W. Illinois Ave ~ Aurora, IL 60506

> 630-859-0333 FAX 630-859-0114

>

> Sample newsletter

> http://www.theCompounder.com/NL-Sample.html

>

> Any health related information on our web pages or

> in our newsletters is for educational purposes only.

> None of the information we provide is to be

> construed as medical advice. Before applying any

> therapy or use of herbs, you may want to seek

> advice from your health care professional.

> Our information should not be a substitute for

> physician evaluation or treatment by a health care

> professional and is not intended to provide or

> confirm a diagnosis.

> ----- Original Message -----

> From: n Quinn

> low dose naltrexone

> Sent: Friday, March 05, 2004 11:29 AM

> Subject: Re: [low dose naltrexone] STABILITY OF NALTREXONE

>

>

> Larry,

> I used to use Methylcellolose in formulating mouth-

ulcer " dressings " . It still dissolves very quickly, so would not

affect dissolution of Naltx in the gut..?

> Also I note the stability data, but would have concerns about

contamination from opning/closing the bottle every day, and would

still put a short life on a bottle of (preservative free) natrexone

in water)

> n

> ----- Original Message -----

> From: Larry J. Frieders

> low dose naltrexone

> Sent: Thursday, March 04, 2004 3:00 PM

> Subject: Re: [low dose naltrexone] STABILITY OF NALTREXONE

>

>

> Trissel's Stability of Compounded Formulations

> Second Edition

> Published in 2000

>

> Larry J. Frieders,RPh |The Compounder

> 575 W. Illinois Ave ~ Aurora, IL 60506

> 630-859-0333 FAX 630-859-0114

>

> Sample newsletter

> http://www.theCompounder.com/NL-Sample.html

>

> Any health related information on our web pages or

> in our newsletters is for educational purposes only.

> None of the information we provide is to be

> construed as medical advice. Before applying any

> therapy or use of herbs, you may want to seek

> advice from your health care professional.

> Our information should not be a substitute for

> physician evaluation or treatment by a health care

> professional and is not intended to provide or

> confirm a diagnosis.

> ----- Original Message -----

> From: n Quinn

> low dose naltrexone

> Sent: Thursday, March 04, 2004 3:17 AM

> Subject: Re: [low dose naltrexone] STABILITY OF NALTREXONE

>

>

> This is excellent, Larry

> what edition..is it recent text, as my compunding supplies'

specialists would only stand by 14 days in a fridge, in their

diluent..1% xanthan in water!

> Information like this is a great help to compounders and

patients, as the liquid formulation is a good bit cheaper, plus its

useful in people with swallowing difficulties.

> n (Compounder and campaigner).. Ireland

> ----- Original Message -----

> From: Larry J. Frieders

> low dose naltrexone

> Sent: Wednesday, March 03, 2004 10:44 PM

> Subject: [low dose naltrexone] STABILITY OF NALTREXONE

>

>

> NOT 1 day... NOT 1 week...BUT a MONTH or MORE!

>

> Naltrexone is quite stable in water.

>

> I am quoting from Trissel's book, " Stability of Compounded

Formulations " , Second Edition, page 266

>

> " Stability-indicating HPLC analysis found less than 10%

loss within 90 days at either 4 degrees C or 25 degrees C; most

samples exhibited no loss. .... The recommended shelf lives of 30

and 60 days stored at 25 degrees C and 4 degrees C, respectively. "

>

> This is a reference book that every compounder OUGHT to

have on hand.

>

> 4 degrees C is refrigeration and 25 degrees C is room

temperature.

>

> We make a lot of naltrexone solutions for people who need

to adjust their doses. The most popular strength is 1mg per ml. We

supply a syringe with which the patient can measure the correct

dose. It is bitter so it needs to be mixed with something (unless

you have strong taste buds). Nobody has ever complained that

it " stopped working " .

>

> Larry J. Frieders,RPh |The Compounder

> 575 W. Illinois Ave ~ Aurora, IL 60506

> 630-859-0333 FAX 630-859-0114

>

> Sample newsletter

> http://www.theCompounder.com/NL-Sample.html

>

> Any health related information on our web pages or

> in our newsletters is for educational purposes only.

> None of the information we provide is to be

> construed as medical advice. Before applying any

> therapy or use of herbs, you may want to seek

> advice from your health care professional.

> Our information should not be a substitute for

> physician evaluation or treatment by a health care

> professional and is not intended to provide or

> confirm a diagnosis.

> ----- Original Message -----

> From: Lynda Phelps

> low dose naltrexone

> Sent: Wednesday, March 03, 2004 6:33 AM

> Subject: Re: [low dose naltrexone] Re: LDN

>

>

> Naltrexone is good for about a week, I was told by a

pharmacist. That is

> why I only dilute half a tablet (25 mg) at a time which

gives me five days

> worth of 4.5 mg. It works fine for me.

>

> HI LYNDA-

> I GET THE TABLET - BUT READ EARLIER ON THIS SITE THAT

> NALTREXONE IS NOT STABLE IN LIQUID FOR AN EXTENDED TIME.

> DOES ANYONE KNOW FOR SURE?

> BESTAUNT

>

>

>

>

> -------------------------------------------------------------------

-----------

>

[Guest guest]

I like Acidophilus no cramps no problems and yes it is working with ldn well.

Reg;

-------Original Message-------

From: low dose naltrexone

Date: 03/05/04 11:38:48

low dose naltrexone

Subject: [low dose naltrexone] Re: STABILITY OF NALTREXONE

Could you answer a filler question for me? I asked my pharmacist what she used as the filler and was told it was acidophilis. She said it would be an immediate release mixture. Just wanted to double check though. Thank you.> Methylcellulose is the standard for retarding dissolution in the gut. I didn't make it up , but I've been following that recommendation for years - and it seems to work, especially when we make the slow release T3. > > When we dispense liquids - especially in aqueous bases - we supply a special cap and syringe. We usually keep the dating around 30 days and I've not heard of a contamination issue from any patients (bottle is kept in refrigerator). I agree that fungal contamination is possible, but how does it play out in reality? I would never leave a bottle for 30 days in a dirty environment like a hospital, but most homes are clean enough to avoid contamination over a 30 day period. Also note that xanthan gum in suspension is more likely to "go bad". I have often seen that stuff grow mold.> > Larry J. Frieders,RPh |The Compounder> 575 W. Illinois Ave ~ Aurora, IL 60506 > 630-859-0333 FAX 630-859-0114> > Sample newsletter > http://www.theCompounder.com/NL-Sample.html> > Any health related information on our web pages or > in our newsletters is for educational purposes only. > None of the information we provide is to be > construed as medical advice. Before applying any > therapy or use of herbs, you may want to seek > advice from your health care professional. > Our information should not be a substitute for > physician evaluation or treatment by a health care > professional and is not intended to provide or > confirm a diagnosis. > ----- Original Message ----- > From: n Quinn > low dose naltrexone > Sent: Friday, March 05, 2004 11:29 AM> Subject: Re: [low dose naltrexone] STABILITY OF NALTREXONE> > > Larry,> I used to use Methylcellolose in formulating mouth-ulcer "dressings". It still dissolves very quickly, so would not affect dissolution of Naltx in the gut..?> Also I note the stability data, but would have concerns about contamination from opning/closing the bottle every day, and would still put a short life on a bottle of (preservative free) natrexone in water)> n> ----- Original Message ----- > From: Larry J. Frieders > low dose naltrexone > Sent: Thursday, March 04, 2004 3:00 PM> Subject: Re: [low dose naltrexone] STABILITY OF NALTREXONE> > > Trissel's Stability of Compounded Formulations> Second Edition> Published in 2000> > Larry J. Frieders,RPh |The Compounder> 575 W. Illinois Ave ~ Aurora, IL 60506 > 630-859-0333 FAX 630-859-0114> > Sample newsletter > http://www.theCompounder.com/NL-Sample.html> > Any health related information on our web pages or > in our newsletters is for educational purposes only. > None of the information we provide is to be > construed as medical advice. Before applying any > therapy or use of herbs, you may want to seek > advice from your health care professional. > Our information should not be a substitute for > physician evaluation or treatment by a health care > professional and is not intended to provide or > confirm a diagnosis. > ----- Original Message ----- > From: n Quinn > low dose naltrexone > Sent: Thursday, March 04, 2004 3:17 AM> Subject: Re: [low dose naltrexone] STABILITY OF NALTREXONE> > > This is excellent, Larry> what edition..is it recent text, as my compunding supplies' specialists would only stand by 14 days in a fridge, in their diluent..1% xanthan in water!> Information like this is a great help to compounders and patients, as the liquid formulation is a good bit cheaper, plus its useful in people with swallowing difficulties.> n (Compounder and campaigner).. Ireland> ----- Original Message ----- > From: Larry J. Frieders > low dose naltrexone > Sent: Wednesday, March 03, 2004 10:44 PM> Subject: [low dose naltrexone] STABILITY OF NALTREXONE> > > NOT 1 day... NOT 1 week...BUT a MONTH or MORE!> > Naltrexone is quite stable in water.> > I am quoting from Trissel's book, "Stability of Compounded Formulations", Second Edition, page 266> > "Stability-indicating HPLC analysis found less than 10% loss within 90 days at either 4 degrees C or 25 degrees C; most samples exhibited no loss. .... The recommended shelf lives of 30 and 60 days stored at 25 degrees C and 4 degrees C, respectively."> > This is a reference book that every compounder OUGHT to have on hand. > > 4 degrees C is refrigeration and 25 degrees C is room temperature. > > We make a lot of naltrexone solutions for people who need to adjust their doses. The most popular strength is 1mg per ml. We supply a syringe with which the patient can measure the correct dose. It is bitter so it needs to be mixed with something (unless you have strong taste buds). Nobody has ever complained that it "stopped working". > > Larry J. Frieders,RPh |The Compounder> 575 W. Illinois Ave ~ Aurora, IL 60506 > 630-859-0333 FAX 630-859-0114> > Sample newsletter > http://www.theCompounder.com/NL-Sample.html> > Any health related information on our web pages or > in our newsletters is for educational purposes only. > None of the information we provide is to be > construed as medical advice. Before applying any > therapy or use of herbs, you may want to seek > advice from your health care professional. > Our information should not be a substitute for > physician evaluation or treatment by a health care > professional and is not intended to provide or > confirm a diagnosis. > ----- Original Message ----- > From: Lynda Phelps > low dose naltrexone > Sent: Wednesday, March 03, 2004 6:33 AM> Subject: Re: [low dose naltrexone] Re: LDN> > > Naltrexone is good for about a week, I was told by a pharmacist. That is> why I only dilute half a tablet (25 mg) at a time which gives me five days> worth of 4.5 mg. It works fine for me.> > HI LYNDA-> I GET THE TABLET - BUT READ EARLIER ON THIS SITE THAT> NALTREXONE IS NOT STABLE IN LIQUID FOR AN EXTENDED TIME.> DOES ANYONE KNOW FOR SURE?> BESTAUNT> > > > > ------------------------------------------------------------------------------>