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STABILITY OF NALTREXONE

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NOT 1 day... NOT 1 week...BUT a MONTH or MORE!

Naltrexone is quite stable in water.

I am quoting from Trissel's book, "Stability of Compounded Formulations", Second Edition, page 266

"Stability-indicating HPLC analysis found less than 10% loss within 90 days at either 4 degrees C or 25 degrees C; most samples exhibited no loss. .... The recommended shelf lives of 30 and 60 days stored at 25 degrees C and 4 degrees C, respectively."

This is a reference book that every compounder OUGHT to have on hand.

4 degrees C is refrigeration and 25 degrees C is room temperature.

We make a lot of naltrexone solutions for people who need to adjust their doses. The most popular strength is 1mg per ml. We supply a syringe with which the patient can measure the correct dose. It is bitter so it needs to be mixed with something (unless you have strong taste buds). Nobody has ever complained that it "stopped working".

Larry J. Frieders,RPh |The Compounder575 W. Illinois Ave ~ Aurora, IL 60506 630-859-0333 FAX 630-859-0114 Sample newsletter http://www.theCompounder.com/NL-Sample.html

Any health related information on our web pages or in our newsletters is for educational purposes only. None of the information we provide is to be construed as medical advice. Before applying any therapy or use of herbs, you may want to seek advice from your health care professional. Our information should not be a substitute for physician evaluation or treatment by a health care professional and is not intended to provide or confirm a diagnosis.

----- Original Message -----

From: Lynda Phelps

low dose naltrexone

Sent: Wednesday, March 03, 2004 6:33 AM

Subject: Re: [low dose naltrexone] Re: LDN

Naltrexone is good for about a week, I was told by a pharmacist. That iswhy I only dilute half a tablet (25 mg) at a time which gives me five daysworth of 4.5 mg. It works fine for me.HI LYNDA-I GET THE TABLET - BUT READ EARLIER ON THIS SITE THATNALTREXONE IS NOT STABLE IN LIQUID FOR AN EXTENDED TIME.DOES ANYONE KNOW FOR SURE?BESTAUNT

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