RE: Is a filler really needed?

[Guest guest]

The *filler* is necessary. Each empty capsule can hold a few hundred milligrams (depending on the size). If you are only going to have a 3mg or 4.5mg dose you need something else in the capsule to fill it - hence the term "filler". There is no way to accurately measure 3mg or 4.5mg and place it in the capsule all by itself. If you can see powder in the capsule there is filler in there because you probably couldn't detect 3mg by itself. The only real important issue about fillers for LDN is to use one that is rapid release - that means it doesn't contain any methylcellulose - or other retarding product.

Larry J. Frieders,RPh |The Compounder575 W. Illinois Ave ~ Aurora, IL 60506 630-859-0333 FAX 630-859-0114 Sample newsletter http://www.theCompounder.com/NL-Sample.html

Any health related information on our web pages or in our newsletters is for educational purposes only. None of the information we provide is to be construed as medical advice. Before applying any therapy or use of herbs, you may want to seek advice from your health care professional. Our information should not be a substitute for physician evaluation or treatment by a health care professional and is not intended to provide or confirm a diagnosis.

----- Original Message -----

From:

low dose naltrexone

Sent: Tuesday, March 02, 2004 2:34 PM

Subject: [low dose naltrexone] Is a filler really needed?

Hi everyone,I've been on LDN a little over 3 weeks, after trying different times of the evening I've gotten to a point of realizing that I can finally sleep a good 6 to 8 hours with the help of Alerian root and if I do wake at 3:30 I can usually get back to sleep. Anyway, my question is I've been taking LDN with no fillers, it's a very small capsule 3 MG. I'm using a compounding pharmacy, if I'd like them to fill the capsule with something I'm sure it would not be a problem. Am I missing something, unless a filler could help with the slight stiffness or helping me sleep through the night? The amount of additional energy this enables me to have has been wonderful. Thanks for your comments about sticking with 3.0 for a while longer before moving to 4.5 Looking forward to your thoughts. Have a great day!

[Guest guest]

Boy I bet you get a lot of responses with this one! No filler you say , intriguing I didn't know a pharmacist could measure out only three mgs. into a pill, I thought that the filler was needed to make the volume large enuf to consistently measure acuratly (sp)?And was that Valerian root? As for the stiffness I did a lot of reading on Phenylalanine and Methylcobalamin (Vit B-12) and it sounds like if you start taking 750mgs. per day of phenylalanine the pain and stiffness will after a month be gone. And the Methylcobalamin is "Armour for your nerves" Tests are now being done on M.S. patients using 60mgs. of Methylcobalamin per day and the recovery time using Prednisone and this B-12 is two weeks not the sixty-seven day average of prednisone only. This is from Holistic International Dated May 2001 and yet mainstream Docs. won't recognise it. I have now started this and will keep you informed.

Reg.

-------Original Message-------

From: low dose naltrexone

Date: 03/02/04 13:36:40

low dose naltrexone

Subject: [low dose naltrexone] Is a filler really needed?

Hi everyone,I've been on LDN a little over 3 weeks, after trying different times of the evening I've gotten to a point of realizing that I can finally sleep a good 6 to 8 hours with the help of Alerian root and if I do wake at 3:30 I can usually get back to sleep. Anyway, my question is I've been taking LDN with no fillers, it's a very small capsule 3 MG. I'm using a compounding pharmacy, if I'd like them to fill the capsule with something I'm sure it would not be a problem. Am I missing something, unless a filler could help with the slight stiffness or helping me sleep through the night? The amount of additional energy this enables me to have has been wonderful. Thanks for your comments about sticking with 3.0 for a while longer before moving to 4.5 Looking forward to your thoughts. Have a great day!

____________________________________________________ IncrediMail - Email has finally evolved - Click Here

[Guest guest]

Reg,

I was wrong, my

LDN is filled with 4EMP Methyellose (lactose) it

doesn’t seem to be giving me any problem, so I’m going to continue

with it. I knew there was something

wrong when everyone was using a filler but me. . . lol Live and learn!

The best,

-----Original Message-----

From: Reg Kreil

[mailto:regkreil@...]

Sent: Tuesday, March 02, 2004 4:07

PM

To:

low dose naltrexone

Subject: Re: [low dose naltrexone]

Is a filler really needed?

Boy I bet you get a lot of responses with this one! No

filler you say , intriguing I didn't know a pharmacist could measure out

only three mgs. into a pill, I thought that the filler was needed to make the

volume large enuf to consistently measure acuratly (sp)?And was that Valerian

root? As for the stiffness I did a lot of reading on Phenylalanine and

Methylcobalamin (Vit B-12) and it sounds like if you start taking

750mgs. per day of phenylalanine the pain and stiffness will after a month be

gone. And the Methylcobalamin is " Armour for your nerves " Tests are

now being done on M.S. patients using 60mgs. of Methylcobalamin per day and

the recovery time using Prednisone and this B-12 is two weeks not the

sixty-seven day average of prednisone only. This is from Holistic

International Dated May 2001 and yet mainstream Docs. won't recognise it. I

have now started this and will keep you informed.

Reg.

-------Original Message-------

From: low dose naltrexone

Date: 03/02/04

13:36:40

low dose naltrexone

Subject:

[low dose naltrexone] Is a filler really needed?

Hi everyone,

I've been on LDN a little over 3 weeks, after

trying different times

of the evening I've gotten to a point of realizing

that I can

finally sleep a good 6 to 8 hours with the help

of Alerian root and

if I do wake at 3:30 I can usually get back to

sleep. Anyway, my

question is I've been taking LDN with no

fillers, it's a very small

capsule 3 MG. I'm using a compounding

pharmacy, if I'd like them to

fill the capsule with something I'm sure it

would not be a problem.

Am I missing something, unless a filler could

help with the slight

stiffness or helping me sleep through the

night? The amount of

additional energy this enables me to have has

been wonderful.

Thanks for your comments about sticking with 3.0

for a while longer

before moving to 4.5 Looking forward to

your thoughts. Have a

great day!

____________________________________________________

IncrediMail

- Email has finally evolved - Click Here

[Guest guest]

4EMP Methyellose IS NOT (lactose). It is a methylcellulose that is designed to act as a slow release filler when mixed into a compounder capsule. All of the conversation about LDN strongly suggests that a person NOT use the slow release form (see low dose naltrexone.org). From this perspective methylcellulose is not the best choice of filler.

Every LDN capsule ever made has some type of filler in it. Think of the naltrexone as the blueberries in a blueberry muffin. The muffin is the filler. You have to have the filler to have the muffin - and the muffin contains the blueberries. The capsule filler is similar - it contains the naltrexone.

Other posts point out that an empty capsule will "hold" about 200mg of powder. The LDN is 3mg or 4.5mg. The other stuff in the capsule is the filler. A pharmacist cannot make a capsule without a filler - unless the active ingredient completely fills the empty capsule. The fillers are inert - they have no activity.

Larry J. Frieders,RPh |The Compounder575 W. Illinois Ave ~ Aurora, IL 60506 630-859-0333 FAX 630-859-0114 Sample newsletter http://www.theCompounder.com/NL-Sample.html

Any health related information on our web pages or in our newsletters is for educational purposes only. None of the information we provide is to be construed as medical advice. Before applying any therapy or use of herbs, you may want to seek advice from your health care professional. Our information should not be a substitute for physician evaluation or treatment by a health care professional and is not intended to provide or confirm a diagnosis.

----- Original Message -----

From: Baden

low dose naltrexone

Sent: Thursday, March 04, 2004 4:42 PM

Subject: RE: [low dose naltrexone] Is a filler really needed?

Reg,

I was wrong, my LDN is filled with 4EMP Methyellose (lactose) it doesn’t seem to be giving me any problem, so I’m going to continue with it. I knew there was something wrong when everyone was using a filler but me. . . lol Live and learn!

The best,

-----Original Message-----From: Reg Kreil [mailto:regkreil@...] Sent: Tuesday, March 02, 2004 4:07 PMlow dose naltrexone Subject: Re: [low dose naltrexone] Is a filler really needed?

Boy I bet you get a lot of responses with this one! No filler you say , intriguing I didn't know a pharmacist could measure out only three mgs. into a pill, I thought that the filler was needed to make the volume large enuf to consistently measure acuratly (sp)?And was that Valerian root? As for the stiffness I did a lot of reading on Phenylalanine and Methylcobalamin (Vit B-12) and it sounds like if you start taking 750mgs. per day of phenylalanine the pain and stiffness will after a month be gone. And the Methylcobalamin is "Armour for your nerves" Tests are now being done on M.S. patients using 60mgs. of Methylcobalamin per day and the recovery time using Prednisone and this B-12 is two weeks not the sixty-seven day average of prednisone only. This is from Holistic International Dated May 2001 and yet mainstream Docs. won't recognise it. I have now started this and will keep you informed.

Reg.

-------Original Message-------

From: low dose naltrexone

Date: 03/02/04 13:36:40

low dose naltrexone

Subject: [low dose naltrexone] Is a filler really needed?

Hi everyone,I've been on LDN a little over 3 weeks, after trying different times of the evening I've gotten to a point of realizing that I can finally sleep a good 6 to 8 hours with the help of Alerian root and if I do wake at 3:30 I can usually get back to sleep. Anyway, my question is I've been taking LDN with no fillers, it's a very small capsule 3 MG. I'm using a compounding pharmacy, if I'd like them to fill the capsule with something I'm sure it would not be a problem. Am I missing something, unless a filler could help with the slight stiffness or helping me sleep through the night? The amount of additional energy this enables me to have has been wonderful. Thanks for your comments about sticking with 3.0 for a while longer before moving to 4.5 Looking forward to your thoughts. Have a great day!

____________________________________________________ IncrediMail - Email has finally evolved - Click Here

[Guest guest]

Thank you so much for your response

Larry, O.K. so now I’ve got a

prescription of LDN with a slow release filler. . .do you and the members feel strongly

that I somehow get another script from my doctor with a fast release filler? It’s

a 2 month supply, even with this slow release, I feel

energized and even “jiddery” for quite a

few hours of the day. With fast

release, I can’t imagine getting a large amount of uninterrupted sleep? When

I do get the fast release can I have them fill it with calcium? I realize there are several questions in

this post, and I truly appreciate you time in responding. I don’t know what I would do without

this group that are in “the know” about

LDN, our doctors certainly are not YET, Hopefully as a powerful group we can

change that! I look forward to

everyone’s thoughts. Count me in on e-mailing Montel

too!

Have a great weekend,

-----Original Message-----

From: Larry J. Frieders

[mailto:larry@...]

Sent: Thursday, March 04, 2004 6:35 PM

To:

low dose naltrexone

Subject: Re: [low dose naltrexone]

Is a filler really needed?

4EMP Methyellose IS

NOT (lactose). It is a methylcellulose that is designed to act as a slow

release filler when mixed into a compounder capsule. All of the

conversation about LDN strongly suggests that a person NOT use the slow release

form (see low dose naltrexone.org). From this perspective methylcellulose

is not the best choice of filler.

Every LDN capsule ever

made has some type of filler in it. Think of the naltrexone as the

blueberries in a blueberry muffin. The muffin is the filler. You

have to have the filler to have the muffin - and the muffin contains the

blueberries. The capsule filler is similar - it contains the naltrexone.

Other posts point out

that an empty capsule will " hold " about 200mg of powder. The

LDN is 3mg or 4.5mg. The other stuff in the capsule is the filler.

A pharmacist cannot make a capsule without a filler - unless the active

ingredient completely fills the empty capsule. The fillers are inert -

they have no activity.

Larry J. Frieders,RPh |The Compounder

575 W. Illinois Ave

~ Aurora, IL 60506

630-859-0333 FAX 630-859-0114

Sample newsletter

http://www.theCompounder.com/NL-Sample.html

Any health related information on our web pages or

in our newsletters is for educational purposes only.

None of the information we provide is to be

construed as medical advice. Before applying any

therapy or use of herbs, you may want to seek

advice from your health care professional.

Our information should not be a substitute for

physician evaluation or treatment by a health care

professional and is not intended to provide or

confirm a diagnosis.

----- Original Message -----

From: Baden

low dose naltrexone

Sent: Thursday, March 04, 2004 4:42 PM

Subject: RE:

[low dose naltrexone] Is a filler really needed?

Reg,

I was wrong, my LDN is

filled with 4EMP Methyellose (lactose) it doesn’t seem to be giving me

any problem, so I’m going to continue with it. I knew there was something wrong when

everyone was using a filler but me. . . lol Live and learn!

The best,

-----Original Message-----

From: Reg Kreil

[mailto:regkreil@...]

Sent: Tuesday, March 02, 2004 4:07 PM

To:

low dose naltrexone

Subject: Re: [low dose naltrexone]

Is a filler really needed?

Boy I bet you get a lot of responses with this one! No

filler you say , intriguing I didn't know a pharmacist could measure out

only three mgs. into a pill, I thought that the filler was needed to make the

volume large enuf to consistently measure acuratly (sp)?And was that Valerian

root? As for the stiffness I did a lot of reading on Phenylalanine and

Methylcobalamin (Vit B-12) and it sounds like if you start taking

750mgs. per day of phenylalanine the pain and stiffness will after a month be

gone. And the Methylcobalamin is " Armour for your nerves " Tests are

now being done on M.S. patients using 60mgs. of Methylcobalamin per day and

the recovery time using Prednisone and this B-12 is two weeks not the

sixty-seven day average of prednisone only. This is from Holistic International

Dated May 2001 and yet mainstream Docs. won't recognise it. I have now

started this and will keep you informed.

Reg.

-------Original Message-------

From: low dose naltrexone

Date: 03/02/04 13:36:40

low dose naltrexone

Subject:

[low dose naltrexone] Is a filler really needed?

Hi everyone,

I've been on LDN a little over 3 weeks, after

trying different times

of the evening I've gotten to a point of

realizing that I can

finally sleep a good 6 to 8 hours with the help

of Alerian root and

if I do wake at 3:30 I can usually get back to

sleep. Anyway, my

question is I've been taking LDN with no

fillers, it's a very small

capsule 3 MG. I'm using a compounding

pharmacy, if I'd like them to

fill the capsule with something I'm sure it

would not be a problem.

Am I missing something, unless a filler could

help with the slight

stiffness or helping me sleep through the

night? The amount of

additional energy this enables me to have has

been wonderful.

Thanks for your comments about sticking with 3.0

for a while longer

before moving to 4.5 Looking forward to

your thoughts. Have a

great day!

____________________________________________________

IncrediMail

- Email has finally evolved - Click Here

[Guest guest]

It is my understanding that if one mixes the slow release powder out of the

capsule with water it will then be fast release. Does anyone else have any

comments about this?

Original Message:

-----------------

From: Baden lbaden@...

Date: Fri, 5 Mar 2004 14:00:23 -0500

low dose naltrexone

Subject: RE: [low dose naltrexone] Is a filler really needed?

Thank you so much for your response Larry, O.K. so now I've got a

prescription of LDN with a slow release filler. . .do you and the

members feel strongly that I somehow get another script from my doctor

with a fast release filler? It's a 2 month supply, even with this slow

release, I feel energized and even " jiddery " for quite a few hours of

the day. With fast release, I can't imagine getting a large amount of

uninterrupted sleep? When I do get the fast release can I have them fill

it with calcium? I realize there are several questions in this post,

and I truly appreciate you time in responding. I don't know what I

would do without this group that are in " the know " about LDN, our

doctors certainly are not YET, Hopefully as a powerful group we can

change that! I look forward to everyone's thoughts. Count me in on

e-mailing Montel too!

Have a great weekend,

-----Original Message-----

From: Larry J. Frieders [mailto:larry@...]

Sent: Thursday, March 04, 2004 6:35 PM

low dose naltrexone

Subject: Re: [low dose naltrexone] Is a filler really needed?

4EMP Methyellose IS NOT (lactose). It is a methylcellulose that is

designed to act as a slow release filler when mixed into a compounder

capsule. All of the conversation about LDN strongly suggests that a

person NOT use the slow release form (see low dose naltrexone.org). From

this perspective methylcellulose is not the best choice of filler.

Every LDN capsule ever made has some type of filler in it. Think of the

naltrexone as the blueberries in a blueberry muffin. The muffin is the

filler. You have to have the filler to have the muffin - and the muffin

contains the blueberries. The capsule filler is similar - it contains

the naltrexone.

Other posts point out that an empty capsule will " hold " about 200mg of

powder. The LDN is 3mg or 4.5mg. The other stuff in the capsule is the

filler. A pharmacist cannot make a capsule without a filler - unless

the active ingredient completely fills the empty capsule. The fillers

are inert - they have no activity.

Larry J. Frieders,RPh |The Compounder

575 W. Illinois Ave ~ Aurora, IL 60506

630-859-0333 FAX 630-859-0114

Sample newsletter

http://www.theCompounder.com/NL-Sample.html

Any health related information on our web pages or

in our newsletters is for educational purposes only.

None of the information we provide is to be

construed as medical advice. Before applying any

therapy or use of herbs, you may want to seek

advice from your health care professional.

Our information should not be a substitute for

physician evaluation or treatment by a health care

professional and is not intended to provide or

confirm a diagnosis.

----- Original Message -----

From: Baden <mailto:lbaden@...>

low dose naltrexone

Sent: Thursday, March 04, 2004 4:42 PM

Subject: RE: [low dose naltrexone] Is a filler really needed?

Reg,

I was wrong, my LDN is filled with 4EMP Methyellose (lactose) it doesn't

seem to be giving me any problem, so I'm going to continue with it. I

knew there was something wrong when everyone was using a filler but me.

.. . lol Live and learn!

The best,

-----Original Message-----

From: Reg Kreil [mailto:regkreil@...]

Sent: Tuesday, March 02, 2004 4:07 PM

low dose naltrexone

Subject: Re: [low dose naltrexone] Is a filler really needed?

Boy I bet you get a lot of responses with this one! No filler you say ,

intriguing I didn't know a pharmacist could measure out only three mgs.

into a pill, I thought that the filler was needed to make the volume

large enuf to consistently measure acuratly (sp)?And was that Valerian

root? As for the stiffness I did a lot of reading on Phenylalanine and

Methylcobalamin (Vit B-12) and it sounds like if you start taking

750mgs. per day of phenylalanine the pain and stiffness will after a

month be gone. And the Methylcobalamin is " Armour for your nerves " Tests

are now being done on M.S. patients using 60mgs. of Methylcobalamin per

day and the recovery time using Prednisone and this B-12 is two weeks

not the sixty-seven day average of prednisone only. This is from

Holistic International Dated May 2001 and yet mainstream Docs. won't

recognise it. I have now started this and will keep you informed.

Reg.

-------Original Message-------

From: low dose naltrexone

Date: 03/02/04 13:36:40

low dose naltrexone

Subject: [low dose naltrexone] Is a filler really needed?

Hi everyone,

I've been on LDN a little over 3 weeks, after trying different times

of the evening I've gotten to a point of realizing that I can

finally sleep a good 6 to 8 hours with the help of Alerian root and

if I do wake at 3:30 I can usually get back to sleep. Anyway, my

question is I've been taking LDN with no fillers, it's a very small

capsule 3 MG. I'm using a compounding pharmacy, if I'd like them to

fill the capsule with something I'm sure it would not be a problem.

Am I missing something, unless a filler could help with the slight

stiffness or helping me sleep through the night? The amount of

additional energy this enables me to have has been wonderful.

Thanks for your comments about sticking with 3.0 for a while longer

before moving to 4.5 Looking forward to your thoughts. Have a

great day!

____________________________________________________

<http://www.incredimail.com/redir.asp?ad_id=309 & lang=9> IncrediMail -

Email has finally evolved -

<http://www.incredimail.com/redir.asp?ad_id=309 & lang=9> Click Here

[Guest guest]

Unless we do it way different here in Canada or maybe small town Alberta, when I need to change something in my capsules like the filler for instance I just go back to my compounder with the unused pills in the origional bottle and explain what is happening and he builds me new ones based on what I brought back! I have to pay all over again but heck I could have spent the twelve bucks on a sack of beer (really cheap beer) so I don't worry too much. Maybe you could ask your druggist if he would do that? It can't hurt.

Reg.

-------Original Message-------

From: low dose naltrexone

Date: 03/05/04 12:03:56

low dose naltrexone

Subject: RE: [low dose naltrexone] Is a filler really needed?

Thank you so much for your response Larry, O.K. so now I’ve got a prescription of LDN with a slow release filler. . .do you and the members feel strongly that I somehow get another script from my doctor with a fast release filler? It’s a 2 month supply, even with this slow release, I feel energized and even “jiddery” for quite a few hours of the day. With fast release, I can’t imagine getting a large amount of uninterrupted sleep? When I do get the fast release can I have them fill it with calcium? I realize there are several questions in this post, and I truly appreciate you time in responding. I don’t know what I would do without this group that are in “the know” about LDN, our doctors certainly are not YET, Hopefully as a powerful group we can change that! I look forward to everyone’s thoughts. Count me in on e-mailing Montel too!

Have a great weekend,

-----Original Message-----From: Larry J. Frieders [mailto:larry@...] Sent: Thursday, March 04, 2004 6:35 PMlow dose naltrexone Subject: Re: [low dose naltrexone] Is a filler really needed?

4EMP Methyellose IS NOT (lactose). It is a methylcellulose that is designed to act as a slow release filler when mixed into a compounder capsule. All of the conversation about LDN strongly suggests that a person NOT use the slow release form (see low dose naltrexone.org). From this perspective methylcellulose is not the best choice of filler.

____________________________________________________ IncrediMail - Email has finally evolved - Click Here

[Guest guest]

Great idea Reg I’ve been doing 4.5 and I think it’s

actually made me too stiff even jittery at times… I may take mine back

and ask for them to be made to 3.5 and have extra to boot! Even if it is

another fill cost etc… glad I read this one ;o)

From: Reg Kreil

[mailto:regkreil@...]

Sent: Friday, March 05, 2004 4:40

PM

To:

low dose naltrexone

Subject: RE: [low dose naltrexone]

Is a filler really needed?

Unless we do it

way different here in Canada or maybe small town Alberta, when I need to

change something in my capsules like the filler for instance I just go back

to my compounder with the unused pills in the origional bottle and explain

what is happening and he builds me new ones based on what I brought back! I

have to pay all over again but heck I could have spent the twelve bucks on a

sack of beer (really cheap beer) so I don't worry too much. Maybe you could

ask your druggist if he would do that? It can't hurt.

Reg.

-------Original

Message-------

From: low dose naltrexone

Date: 03/05/04 12:03:56

low dose naltrexone

Subject: RE:

[low dose naltrexone] Is a filler really needed?

Thank you so much for your response

Larry, O.K. so now I’ve got a prescription of LDN with a slow release

filler. . .do you and the members feel strongly that I somehow get another

script from my doctor with a fast release filler? It’s a 2 month

supply, even with this slow release, I feel

energized and even “jiddery” for quite

a few hours of the day. With fast release, I can’t imagine getting a

large amount of uninterrupted sleep? When I do get the fast release can I

have them fill it with calcium? I realize there are several questions in

this post, and I truly appreciate you time in responding. I don’t know

what I would do without this group that are in “the

know” about LDN, our doctors certainly are not YET, Hopefully as

a powerful group we can change that! I look forward to everyone’s

thoughts. Count me in on e-mailing Montel too!

Have a great weekend,

-----Original Message-----

From: Larry J. Frieders

[mailto:larry@...]

Sent: Thursday,

March 04, 2004 6:35 PM

To:

low dose naltrexone

Subject: Re: [low dose naltrexone]

Is a filler really needed?

4EMP

Methyellose IS NOT (lactose). It is a methylcellulose that is

designed to act as a slow release filler when mixed into a compounder

capsule. All of the conversation about LDN strongly suggests that a

person NOT use the slow release form (see low dose naltrexone.org). From

this perspective methylcellulose is not the best choice of filler.

____________________________________________________

IncrediMail - Email has finally evolved - Click Here

[Guest guest]

Experience indicates that the fast release formulas are preferred. But, there are no scientific studies to PROVE that - just as there are none to prove that LDN does anything at all.

I don't really think the emphasis on fillers is all that critical. Your experience with LDN compounded with methylcellulose seems to suggest that the filler is less important than a lot of people think. Yes, yes - fillers are important, but fixating on them seems counter-productive. Pharmacists chatter about the benefits of one or another filler, but in the end most fillers are just fine for most people.

We use a filler that contains lactobacillus, magnesium stearate, zinc oxide and calcium carbonate. Why? Well, we try NOT to use lactose (the MOST common capsule filler) because some people are sensitive (and people with chronic conditions seem to be sensitive more often). Why ALL THOSE INGREDIENTS? First, we want something inert - calcium carbonate, zinc oxide and magnesium stearate are inert and they are not absorbed. Next, we'd prefer some granularity - granules are easier to pack in a capsule than fluffy powders. That's why we add lactobacillus. It is somewhat granular and makes our mixture easier to work with - not as easy as lactose, but easier than calcium carbonate alone. Lactobacillus acidophilus is not absorbed but it does offer a benefit. It is one of the beneficial microorganisms in our gut. I recommend that everybody take at least one probiotic capsule a day (lactobacillus is a probiotic). So, as I think it is good for everyone, I have no concerns about adding it to our filler base.

Back to your concern. It is likely that even with the methylcellulose your naltrexone is being absorbed well and the effect is ok. I'd say trust the competence of your compounder and use the product you have. If you are concerned - or want a change - talk to the compounder. Most I know would gladly help by adjusting the formulation for you. Compounders do compounding primarily because people need our services - not to make tons of cashola. That may not be true for all, but I think you will find that the vast majority of compounders genuinely want to serve their customers.

Larry J. Frieders,RPh |The Compounder575 W. Illinois Ave ~ Aurora, IL 60506 630-859-0333 FAX 630-859-0114 Sample newsletter http://www.theCompounder.com/NL-Sample.html

Any health related information on our web pages or in our newsletters is for educational purposes only. None of the information we provide is to be construed as medical advice. Before applying any therapy or use of herbs, you may want to seek advice from your health care professional. Our information should not be a substitute for physician evaluation or treatment by a health care professional and is not intended to provide or confirm a diagnosis.

----- Original Message -----

From: Baden

low dose naltrexone

Sent: Friday, March 05, 2004 1:00 PM

Subject: RE: [low dose naltrexone] Is a filler really needed?

Thank you so much for your response Larry, O.K. so now I’ve got a prescription of LDN with a slow release filler. . .do you and the members feel strongly that I somehow get another script from my doctor with a fast release filler? It’s a 2 month supply, even with this slow release, I feel energized and even “jiddery” for quite a few hours of the day. With fast release, I can’t imagine getting a large amount of uninterrupted sleep? When I do get the fast release can I have them fill it with calcium? I realize there are several questions in this post, and I truly appreciate you time in responding. I don’t know what I would do without this group that are in “the know” about LDN, our doctors certainly are not YET, Hopefully as a powerful group we can change that! I look forward to everyone’s thoughts. Count me in on e-mailing Montel too!

Have a great weekend,

-----Original Message-----From: Larry J. Frieders [mailto:larry@...] Sent: Thursday, March 04, 2004 6:35 PMlow dose naltrexone Subject: Re: [low dose naltrexone] Is a filler really needed?

4EMP Methyellose IS NOT (lactose). It is a methylcellulose that is designed to act as a slow release filler when mixed into a compounder capsule. All of the conversation about LDN strongly suggests that a person NOT use the slow release form (see low dose naltrexone.org). From this perspective methylcellulose is not the best choice of filler.

Every LDN capsule ever made has some type of filler in it. Think of the naltrexone as the blueberries in a blueberry muffin. The muffin is the filler. You have to have the filler to have the muffin - and the muffin contains the blueberries. The capsule filler is similar - it contains the naltrexone.

Other posts point out that an empty capsule will "hold" about 200mg of powder. The LDN is 3mg or 4.5mg. The other stuff in the capsule is the filler. A pharmacist cannot make a capsule without a filler - unless the active ingredient completely fills the empty capsule. The fillers are inert - they have no activity.

Larry J. Frieders,RPh |The Compounder575 W. Illinois Ave ~ Aurora, IL 60506 630-859-0333 FAX 630-859-0114 Sample newsletter http://www.theCompounder.com/NL-Sample.html

Any health related information on our web pages or in our newsletters is for educational purposes only. None of the information we provide is to be construed as medical advice. Before applying any therapy or use of herbs, you may want to seek advice from your health care professional. Our information should not be a substitute for physician evaluation or treatment by a health care professional and is not intended to provide or confirm a diagnosis.

----- Original Message -----

From: Baden

low dose naltrexone

Sent: Thursday, March 04, 2004 4:42 PM

Subject: RE: [low dose naltrexone] Is a filler really needed?

Reg,

I was wrong, my LDN is filled with 4EMP Methyellose (lactose) it doesn’t seem to be giving me any problem, so I’m going to continue with it. I knew there was something wrong when everyone was using a filler but me. . . lol Live and learn!

The best,

-----Original Message-----From: Reg Kreil [mailto:regkreil@...] Sent: Tuesday, March 02, 2004 4:07 PMlow dose naltrexone Subject: Re: [low dose naltrexone] Is a filler really needed?

Boy I bet you get a lot of responses with this one! No filler you say , intriguing I didn't know a pharmacist could measure out only three mgs. into a pill, I thought that the filler was needed to make the volume large enuf to consistently measure acuratly (sp)?And was that Valerian root? As for the stiffness I did a lot of reading on Phenylalanine and Methylcobalamin (Vit B-12) and it sounds like if you start taking 750mgs. per day of phenylalanine the pain and stiffness will after a month be gone. And the Methylcobalamin is "Armour for your nerves" Tests are now being done on M.S. patients using 60mgs. of Methylcobalamin per day and the recovery time using Prednisone and this B-12 is two weeks not the sixty-seven day average of prednisone only. This is from Holistic International Dated May 2001 and yet mainstream Docs. won't recognise it. I have now started this and will keep you informed.

Reg.

-------Original Message-------

From: low dose naltrexone

Date: 03/02/04 13:36:40

low dose naltrexone

Subject: [low dose naltrexone] Is a filler really needed?

Hi everyone,I've been on LDN a little over 3 weeks, after trying different times of the evening I've gotten to a point of realizing that I can finally sleep a good 6 to 8 hours with the help of Alerian root and if I do wake at 3:30 I can usually get back to sleep. Anyway, my question is I've been taking LDN with no fillers, it's a very small capsule 3 MG. I'm using a compounding pharmacy, if I'd like them to fill the capsule with something I'm sure it would not be a problem. Am I missing something, unless a filler could help with the slight stiffness or helping me sleep through the night? The amount of additional energy this enables me to have has been wonderful. Thanks for your comments about sticking with 3.0 for a while longer before moving to 4.5 Looking forward to your thoughts. Have a great day!

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