Guest guest Posted March 6, 2004 Report Share Posted March 6, 2004 Here's Dr. Klenner's original paper http://thecompounder.com/diseaseklennerpaper.html Larry J. Frieders,RPh |The Compounder575 W. Illinois Ave ~ Aurora, IL 60506 630-859-0333 FAX 630-859-0114 Sample newsletter http://www.theCompounder.com/NL-Sample.html Any health related information on our web pages or in our newsletters is for educational purposes only. None of the information we provide is to be construed as medical advice. Before applying any therapy or use of herbs, you may want to seek advice from your health care professional. Our information should not be a substitute for physician evaluation or treatment by a health care professional and is not intended to provide or confirm a diagnosis. ----- Original Message ----- From: tmbayuk A Home away from Home a MS Support Board ; mscured ; msalternatives ; low dose naltrexone ; MSViews_Multiple_Sclerosis ; MSfriends Sent: Saturday, March 06, 2004 12:38 PM Subject: [low dose naltrexone] Benfotiamine Hi Everyone, From the mid 1930's to the 1950's there was a Doctor Klenner in North Carolina that had very significant success treating ms'er's with Vitamin B 1 ( Thiamine) injections. The following is a lipid form of B 1 that is absorbed by our bodies much more efficiently. B 1 is absolutely essential for healthy nerves. Regards, Tom Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic retinopathy.Hammes HP, Du X, Edelstein D, Taguchi T, Matsumura T, Ju Q, Lin J, Bierhaus A, Nawroth P, Hannak D, Neumaier M, Bergfeld R, Giardino I, Brownlee M.Medical Clinic V School of Clinical MedicineMannheim, Germany.Nat Med. 2003 Mar;9(3):294-9Abstract Three of the major biochemical pathways implicated in the pathogenesis of hyperglycemia induced vascular damage (the hexosamine pathway, the advanced glycation end product (AGE) formation pathway and the diacylglycerol (DAG)-protein kinase C (PKC) pathway) are activated by increased availability of the glycolytic metabolites glyceraldehyde-3-phosphate and fructose-6-phosphate. We have discovered that the lipid-soluble thiamine derivative benfotiamine can inhibit these three pathways, as well as hyperglycemia-associated NF-kappaB activation, by activating the pentose phosphate pathway enzyme transketolase, which converts glyceraldehyde-3-phosphate and fructose-6-phosphate into pentose-5-phosphates and other sugars. In retinas of diabetic animals, benfotiamine treatment inhibited these three pathways and NF-kappaB activation by activating transketolase, and also prevented experimental diabetic retinopathy. The ability of benfotiamine to inhibit three major pathways simultaneously might be clinically useful in preventing the development and progression of diabetic complications. Galantamine | Memantine | Vinpocetine | Idebenone | Pyritinol | cataractPicamilon | Modafinil | CDP Choline | Deprenyl | Piracetam | stroke | Pyridoxamine | Home | 1. Benfotiamine prevents diabetic side effects 2. Benfotiamine a new approach to preventing diabetic retinopathy 3. Benfotiamine delays formation of advanced glycosylation end-products 4. Benfotiamine effectiveness in diabetic neuropathy 5. Benfotiamine efficacy in diabetic polyneuropathy 6. Benfotiamine efficacy in patients diabetic neuropathy 7. Benfotiamine bioavailability 8. Benfotiamine treatment of diabetic polyneuropathy 9. Benfotiamine is indicated in end-stage renal disease 10. Benfotiamine may prevent diabetic complications 11. Benfotiamine inhibits formation of advanced glycation end products 12. Benfotiamine suppressed the formation of advanced glycation end products Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 6, 2004 Report Share Posted March 6, 2004 Hi Larry, Thank you , great info. Regards, Tom Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 10, 2004 Report Share Posted April 10, 2004 Since the B vitamins are excreted in the urine it would make sense to divide the daily dosage into several smaller doses. Your body does not store the water soluble vitamins... However, I find I end up missing any mid day dose, so I take mine in the morning and evening. ----- Original Message ----- From: " russomom3 " <debbie_russo@...> <low dose naltrexone > Sent: Saturday, April 10, 2004 10:06 AM Subject: [low dose naltrexone] benfotiamine > I've order 150mg capsules (tablets) of benfotiamine. How much is > everyone taking and how often? I saw some info on their website > about 600mgs a day, but is this 300mg twice a day, 150 mgs four > times a day? Need it for help with neuropathic pain. LDN has not > helped with this at all. Help! > > Debbie > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 10, 2004 Report Share Posted April 10, 2004 At 10:35 AM 4/10/2004, wrote: > >Since the B vitamins are excreted in the urine it would make sense >to divide the daily dosage into several smaller doses. Your body >does not store the water soluble vitamins... Benfotiamine is lipid soluble ( not water soluble ). See : low dose naltrexone/message/8052 Bill | Quote Link to comment Share on other sites More sharing options...
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