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My daughter was doing very well on 3mg - has been on since

September. But she still cannot walk - she has SPMS. Her dr. is

trying the higher dosage of 4.5 - she has been on it since Monday, 7

days, and since the second day has been so tired she cannot do much

of anything - sleeps most of the time. Otherwise no bad side

effects, except for loss of appetite which I imagine comes with the

tiredness. She wants to go back to the 3mg immediately. Her dr.

wants her to try another few weeks. I find her not so mentally

responsive and she is definitely not happy - she is usually a very

upbeat and happy person, in spite of the ms. Has anyone gone

through this and what are your suggestions? I think you are all

more " in the loop " than any of the drs. Thanks for your help.

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