Re: Please, I need answers..official medicine only partially works...

[Guest guest]

The reason why official medicine only partially works for MS might be

in the theory behind being completely wrong!!

Tell you neuro to go back to study...

As mine suggestion to you, always keep your immune system strong and

healty instead. Good luck!

from http://www.thisisms.com/article63.html :

Research: Multiple Sclerosis may not be an Auto-Immune Disease

This is a fascinating new study that concludes that MS may not be an

auto-immune disease after all...

" A new view of multiple sclerosis (MS) may arise from the first

extensive study of brain tissue from the earliest hours during a bout

of the disease. The results...suggest that the earliest event is not,

as previously believed, a misguided immune system attack on a brain

substance called myelin...

Instead, the first event appears to be the death of the brain cells

that produce myelin, triggering a subsequent immune system mop-up

operation to clean up the cells and the myelin, said author W.

Prineas, MBBS, of the University of Sydney in Australia...

The results could have significant consequences for MS research, much

of which is focused on understanding why the immune system attacks

myelin. The focus may have to shift to understanding why the myelin-

producing cells begin to die. "

click " read more " for the full article...

Full Article Text

ANNALS OF NEUROLOGY News Alert

Wiley & Sons, Inc.

February 18, 2004

Embargo date: February 23, 2004 at 12:00AM, EST

Multiple Sclerosis

New Data Challenge Theories Of Multiple Sclerosis

Earliest Pathology Exams Uncover Unexpected Cell Death

A new view of multiple sclerosis (MS) may arise from the first

extensive study of brain tissue from the earliest hours during a bout

of the disease. The results, published February 23, 2004, in the

online edition of the ls of Neurology, suggest that the earliest

event is not, as previously believed, a misguided immune system

attack on a brain substance called myelin. The full study will be

available on February 23 via Wiley InterScience

(http://www.interscience.wiley.com/annalsofneurology).

Instead, the first event appears to be the death of the brain cells

that produce myelin, triggering a subsequent immune system mop-up

operation to clean up the cells and the myelin, said author W.

Prineas, MBBS, of the University of Sydney in Australia.

Multiple sclerosis is an enigmatic disorder of the nerve fibers of

the brain and spinal cord. Scarring (sclerosis) replaces myelin,

which normally insulates the nerves from damage and speeds electrical

conduction through the fibers.

Depending on which nerve fibers are hindered, patients can experience

problems ranging from weakness and clumsiness to numbness, visual

disturbances, and even emotional and intellectual alterations. In

some patients, MS manifests itself in cycles of relapse and

remission; in other patients, the disease may progress to a stage of

severe debilitation, either slowly or rapidly.

According to Prineas, the study he conducted with co-author

H. Barnett, MBBS, began several years ago while he was working at the

New Jersey Medical School in Newark. A fellow neuropathologist in

Manhattan asked whether Prineas and his colleagues would be

interested in examining brain tissue from a 14-year-old girl who died

unexpectedly 17 hours into a relapse.

Sudden death can occur in MS if the damage (or lesion) occurs in

parts of the brain that control vital functions such as breathing and

blood circulation.

" This patient proved to be unique in the history of multiple

sclerosis in that there was lesion available for study that was less

than a day old, " said Prineas.

According to the dominant theory of MS, when the researchers examined

the hours-old lesion, they should have found the beginnings of an

immune system attack.

But Prineas and Barnett noticed that the myelin in the lesion was

still intact, and there was no evidence that the typical armada of

immune system cells and molecules had moved into the area yet.

Instead, oligodendrocytes cells, which produce the myelin, were

dying. Myelin is, in fact, an extension of oligodendrocytes that

wraps itself around nearby nerve fibers.

" This encouraged us to re-examine other early MS cases in our brain

bank, " said Prineas. " Similar lesions, albeit extremely rare, were

identified in a number of other early MS cases, which allowed us to

conclude that the changes observed probably occur at the onset of any

typical new lesion. "

The results could have significant consequences for MS research, much

of which is focused on understanding why the immune system attacks

myelin. The focus may have to shift to understanding why the myelin-

producing cells begin to die.

" The important point, at this stage of our investigation, seems to be

that we have no laboratory model for this sort of pathology, " said

Prineas.

Article: " Relapsing and Remitting Multiple Sclerosis:

Pathology of the Newly Forming Lesion, " by H.

Barnett, MBBS and W. Prineas, MBBBS, ls of

Neurology online edition; February 23, 2004.