Guest guest Posted January 23, 2000 Report Share Posted January 23, 2000 >Hi, > >Thanks for this article! It sounds to this unmedical mind that if DNA and >genes are involved, then mitochrondrical damage could occur. >Remember me bringing up mito's before? I am now on 2 lists and these >people have symptoms like ours - weakness, brain dysfunction, exercise >intolerance, breathing and cardio problems (for some of us), endochrine >abnromalities, etc. I still wonder if this is not another facet of CFS - >many on Mito adult list were dx'ed with CFS before alert doctor skipped the >antidep. tx and tried to find a real diagnosis. Outcome is similiar though >- tx with expensive supplements esp. Co-Q 10, caritinine and vitimins. >Probably some whey would help these people too! > >Just rambling, > >Christie What are your to mitochondria list web site addresses???? best, beth Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 26, 2000 Report Share Posted February 26, 2000 Hi, http://www.iwindow.com/mito/ http://www.mdausa.org/ Hope these help! CHristie At 07:20 PM 1/23/00 -0000, you wrote: >From: esp <esp@...> > >>Hi, >> >>Thanks for this article! It sounds to this unmedical mind that if DNA and >>genes are involved, then mitochrondrical damage could occur. >>Remember me bringing up mito's before? I am now on 2 lists and these >>people have symptoms like ours - weakness, brain dysfunction, exercise >>intolerance, breathing and cardio problems (for some of us), endochrine >>abnromalities, etc. I still wonder if this is not another facet of CFS - >>many on Mito adult list were dx'ed with CFS before alert doctor skipped the >>antidep. tx and tried to find a real diagnosis. Outcome is similiar though >>- tx with expensive supplements esp. Co-Q 10, caritinine and vitimins. >>Probably some whey would help these people too! >> >>Just rambling, >> >>Christie >What are your to mitochondria list web site addresses???? best, beth > >--------------------------- Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 9, 2004 Report Share Posted January 9, 2004 Hello-- I hate to look as if am belaboring a point, but aren't the cells with their axons microscopic in scale? That is, if you place electrodes inches apart, how do you detect the difference between the top and bottom of a cell? Are they lined up like batteries in a flashlight? And if so, would they add together to increase the voltage difference with each cell in the series? Wouldn't the hills and valleys interfere with this, since sideways positioning seems to be important, or are we just interested in the total built-up difference along the length of the series? Thanks, Gene >If the neuron is parallel to the line between the sensors, one sensor will see the negative >end and the other will see the positive end, and there will be a significant difference >between the readings at the two points. Neurons that are perpendicular (more or less) >to the line of measurement will not be " seen " , because each of the sensors will read the >positive and negative ends of the neuron, so the signal will be about the same in both >places and, when you subtract one from the other, the result will be close to zero. >Neurons that are a lot closer to one sensor than the other will be more strongly read at >that sensor. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 9, 2004 Report Share Posted January 9, 2004 Gene, What you are describing is the basis of " volume conductor " theory, which does explain how we measure external potentials from cells. Yes, each cell is very small, but there are thousands of them, and their membrane potentials are many millivolts. We are not measuring axonal spike potentials, but we are seeing the slow postsynaptic potentials as well as potentials built up along the " hillocks " of the cells. By the time the currents add up and appear at the scalp, you measure a microvolt potential. Yes, there is a lot of " series " as well as " parallel " combination. When the sources act in a synchronous way (in unison) the external field is greater, hence more measurable. And yes, positioning is crucial. There is a " cosine " in the mathematical expression for the external potential. We primarily measure cells that are parallel to a line connecting the two electrodes. Tom Re: Digest Number 606 > Hello-- > > I hate to look as if am belaboring a point, but aren't the cells with their > axons microscopic in scale? That is, if you place electrodes inches apart, > how do you detect the difference between the top and bottom of a cell? Are > they lined up like batteries in a flashlight? And if so, would they add > together to increase the voltage difference with each cell in the series? > Wouldn't the hills and valleys interfere with this, since sideways > positioning seems to be important, or are we just interested in the total > built-up difference along the length of the series? > > Thanks, > Gene > > >If the neuron is parallel to the line between the sensors, one sensor will > see the negative >end and the other will see the positive end, and there > will be a significant difference >between the readings at the two points. > Neurons that are perpendicular (more or less) >to the line of measurement > will not be " seen " , because each of the sensors will read the >positive and > negative ends of the neuron, so the signal will be about the same in both > >places and, when you subtract one from the other, the result will be close > to zero. >Neurons that are a lot closer to one sensor than the other will > be more strongly read at >that sensor. > > > > > > Quote Link to comment Share on other sites More sharing options...
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