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LDN and PPMS

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Steve,

I have RRMS, and have seen remarkable results in my three months of

taking LDN......but the changes have been ever-so-sligh. With a more

severe form of MS, is it posible that you are just not " seeing " the

slight changes? It is something which might take longer to

actually " see,or feel " changes as they are happening.

Please do not give up on the drug, as there has been so much

success.

Pam

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On Wed, 21 Apr 2004 22:33:08 -0000, you wrote:

>

>Steve,

>

>I have RRMS, and have seen remarkable results in my three months of

>taking LDN......but the changes have been ever-so-sligh. With a more

>severe form of MS, is it posible that you are just not " seeing " the

>slight changes? It is something which might take longer to

>actually " see,or feel " changes as they are happening.

The changes were obvious when I started LDN in October 2002 and I

seemed to be improving. That lasted three months. After that the MS

carried on down hill. The side effects got worse as well so I needed

to reduce the dose. I could no longer cope with the cramps and muscle

stiffness of 4.5mg but I was OK with 3mg. However after a year even

3mg was making my legs too rigid to tolerate.

>

> Please do not give up on the drug, as there has been so much

>success.

>

I haven't given up on LDN but I only take 1.5mg now. On that dose I

have no leg stiffness or cramps. It may be helping, my symptoms have

leveled off. It's difficult to know what is happening because PPMS can

have long periods when it does not get any worse regardless of the

drugs being taken.

Steve

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  • 6 years later...
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,I am treating cancer and asthma - and I take my LDN in the morning. Like you I tried taking it at night but the sleep disturbance was relentless and I had to stop that. Our immune systems don't work properly when we don't get enough sleep.If I were you I would try LDN at other times of day and find what works best. I know of other people who take their LDN during the day - most often in the morning - and have great effects from it. I recently had a scan showing no disease progression, no tumors at all.Plus I feel great.I hope this helps.JackieFrom: kaaren white <kaarenw1@...>Subject: [low dose naltrexone] ldn and ppmslow dose naltrexone Date: Monday, June 28, 2010, 5:07 AM

I am wondering if I should take the LDN in the a.m. morning instead of evening ...

I have been taking the LDN between 9:00 pm. and midnight...and I wake up exhausted at 5-6 in the a.m. and also having very vivid strange dreams from people long ago alot of times in my past...or family....I have always been a night hawk and feel better at night than in the a.m. sometimes waking with rapid heart and feel sweaty I have been taking LDN since March 17, 2010...any suggestions? only med I am taking is 0.25 xanax at night to relax...or maybe a excedrin p.m. had been taking celebrex but stopped that in March....in 2000, and 2001 and in 2004 for sometime I was taking methotrexate and prednisone for RA the LDN has stopped the pain in my joints but I also am glutin free and alot of dairy, am currently waitiing for results from a adrenal gland test for salvia from my doctor as well...am 65 female and weight 118 weight down from staying off the gluten and cheese

kay

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i volunteer on a ptsd site and have ptsd myself, so vivid dreams can always be a problem. not yet on LDN (very very soon, within a couple of wks now), but a man on the site has been telling me about his experience with naltrexone. he takes 50mg every morning. i'm exactly like you, kay, a night owl who feels the best at night, the most energized. i may try morning as well. best ~laura in oregon

http://moineauenfrance.blogspot.com

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He takes 50 mg every morning?!?!?!?!?!?!?!?!?

 

If he does he is not using low dose.  Low dose is typically 3 mg or 4.5 mg.

 

Just an observation.  I am also a night owl and have been taking my LDN at night plus a sleep aide (Melatonin Sleep Science from Whole Foods - Source Naturals made specifically for Whole Foods).  The two together seem to knock me out within a half hour or so.  I sleep better than I have for ... well ever really - and I am more rested.  Night owl + has to go to work in the morning is not a great combo so actually being able to go to sleep at a reasonable time and sleep well is a blessing.

 

Jaxi

On Wed, Jun 30, 2010 at 9:58 AM, Tattoo <moineau@...> wrote:

i volunteer on a ptsd site and have ptsd myself, so vivid dreams can always be a problem. not yet on LDN (very very soon, within a couple of wks now), but a man on the site has been telling me about his experience with naltrexone. he takes 50mg every morning. i'm exactly like you, kay, a night owl who feels the best at night, the most energized. i may try morning as well. best ~laura in oregon

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Once I got my night time saliva cortisol levels down to normal using phosphorylated serine I changed from being a night owl to one who wants to go to sleep prior to 11:00 at night. It used to be common for me to be doing something at 3:00 AM. Being 100% gluten free has made a huge difference in my cortisol levels and now being on LDN I find I sleep better than I have in years and years, and have eliminated the Phos serine and other things I used to take for sleep other than 3 mg melatonin.

K

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I forgot to mention I am also on 20 mg hydrocortisone split in 3 doses four hours apart for worn out adrenals. I tried 's program with adrenal extracts and that just was not enough, I now realize. For the first time in over 30 years I am having some semblance of health and energy. Fibro, Hashi, adrenal insufficiency, celiac and RA. My blood pressure is better and my mood is brighter. Friends notice the difference. K

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