Guest guest Posted November 6, 2003 Report Share Posted November 6, 2003 It does nothing for > mechanical insult like post nasal drip or acid reflux I am curious why it wouldnt help this. I have server post nasal drip and GERD because of it. It usualy flairs up when my Asthma gets bad and vice versa. I was hoping that when I started shots, I would see an improvement in this. If you could elaborate on this I would appr4eciate it. My understanding is that the allergies trigger the postnasl drip and in turn triggers the Asthma and GERD. I shold be starting my shots next month hopefully. Thanks - > My thanks to the person who pointed out the existence of this group. > > I have had excellent results with Xolair so far, starting with a > noticeable increase in peak flow within 12 hours of my first shot, and > now, three months or so in, I can document a peak flow that is more > than double what it used to be and an FEV(1) that is more than double > what it used to be, all on a lower dose of pred. I am still on massive > amounts of medication, but my oral steroid dose IS lower, by about > half (down to 20mg a day) so we are thrilled so far. > > The next big goal will be to see if we can wean off the IgG therapy, > which is even more expensive than the Xolair at the doses I take. > > Xolair definitely makes me less reactive to insult of any kind, so I > have more leeway before I get into big trouble. It does nothing for > mechanical insult like post nasal drip or acid reflux of course BUT > because I am not reacting to the allergic components of my asthma I > don't seem to be on a hair trigger for the other things that cause me > trouble. I agree with the folks who have said that they seem more > stable even if they can't measure a positive change in peak flow. > > As for why the insurance guys are paying...it isn't because of the > cost of inhaled steroids; that is minor compared to the cost of > Xolair. The real savings will be in less hospital time for the severe > asthmatics. One day in hospital is a LOT more than few months of > Xolair! > > Feel free to ask questions about my treatment; I have had very severe > asthma all my life and had pretty much all the various therapies at > various times and I am happy to share what I *think* I know<vbg>. > > P. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 6, 2003 Report Share Posted November 6, 2003 Thank you for sharing your excellent progress to date with the group. It seems that the typical Xolair patients and their insurance companies have paid out enormous amounts of $ in drugs, immunotherapy, various treatments and hospitalizations and the price of Xolair seems small in comparison. It seems amazing to think that many of us are on the verge of a life-changing experience with this new drug! Addy Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 6, 2003 Report Share Posted November 6, 2003 Xolair helps with the allergic component of asthma; so in a sense it would help in that it might decrease the post nasal drip *from allergy*, but if your post nasal drip is from viral illness, for instance, Xolair is not likely to have a direct effect on the viral illness or the drainage from it. By the same token, post nasal drip is only one of many causes of GERD...Xolair is not supposed to directly affect things like GERD caused by drugs or obesity. I did notice a decrease in my sinus drainage after starting Xolair but I cannot say that it is gone completely. Sorry I wasn't more specific about it when I was posting. It was hard for me at first not to expect Xolair to fix everything...my asthma has several components and the Xolair seems to be handling the allergy induced part really well...I was really bummed when I got my first viral illness and bottomed out my peak flows anyway. (Well, gee, it works so well, why not PERFECTLY!?!) Take care, P. > > My thanks to the person who pointed out the existence of this group. > > > > I have had excellent results with Xolair so far, starting with a > > noticeable increase in peak flow within 12 hours of my first shot, and > > now, three months or so in, I can document a peak flow that is more > > than double what it used to be and an FEV(1) that is more than double > > what it used to be, all on a lower dose of pred. I am still on massive > > amounts of medication, but my oral steroid dose IS lower, by about > > half (down to 20mg a day) so we are thrilled so far. > > > > The next big goal will be to see if we can wean off the IgG therapy, > > which is even more expensive than the Xolair at the doses I take. > > > > Xolair definitely makes me less reactive to insult of any kind, so I > > have more leeway before I get into big trouble. It does nothing for > > mechanical insult like post nasal drip or acid reflux of course BUT > > because I am not reacting to the allergic components of my asthma I > > don't seem to be on a hair trigger for the other things that cause me > > trouble. I agree with the folks who have said that they seem more > > stable even if they can't measure a positive change in peak flow. > > > > As for why the insurance guys are paying...it isn't because of the > > cost of inhaled steroids; that is minor compared to the cost of > > Xolair. The real savings will be in less hospital time for the severe > > asthmatics. One day in hospital is a LOT more than few months of > > Xolair! > > > > Feel free to ask questions about my treatment; I have had very severe > > asthma all my life and had pretty much all the various therapies at > > various times and I am happy to share what I *think* I know<vbg>. > > > > P. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 8, 2003 Report Share Posted November 8, 2003 Thats quite alright. I think my GERD was largely casued from post nasl drip from my allergies so I think it should help. I am very excietd at the popssiblity that my asthama may decrease however. I am also intrgued into the fact that my Severe food allergies might also be lessened by Xolair. I know that the clinic trials are still underway, but in theory it should work. - > > > > > > > > It does nothing for > > > mechanical insult like post nasal drip or acid reflux > > > > I am curious why it wouldnt help this. I have server post nasal drip > > and GERD because of it. It usualy flairs up when my Asthma gets bad > > and vice versa. I was hoping that when I started shots, I would see > > an improvement in this. If you could elaborate on this I would > > appr4eciate it. My understanding is that the allergies trigger the > > postnasl drip and in turn triggers the Asthma and GERD. > > > > I shold be starting my shots next month hopefully. > > > > Thanks > > > > - > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > --- In , " keemaka42 " <keemaka42@y...> wrote: > > > My thanks to the person who pointed out the existence of this group. > > > > > > I have had excellent results with Xolair so far, starting with a > > > noticeable increase in peak flow within 12 hours of my first shot, and > > > now, three months or so in, I can document a peak flow that is more > > > than double what it used to be and an FEV(1) that is more than double > > > what it used to be, all on a lower dose of pred. I am still on massive > > > amounts of medication, but my oral steroid dose IS lower, by about > > > half (down to 20mg a day) so we are thrilled so far. > > > > > > The next big goal will be to see if we can wean off the IgG therapy, > > > which is even more expensive than the Xolair at the doses I take. > > > > > > Xolair definitely makes me less reactive to insult of any kind, so I > > > have more leeway before I get into big trouble. It does nothing for > > > mechanical insult like post nasal drip or acid reflux of course BUT > > > because I am not reacting to the allergic components of my asthma I > > > don't seem to be on a hair trigger for the other things that cause me > > > trouble. I agree with the folks who have said that they seem more > > > stable even if they can't measure a positive change in peak flow. > > > > > > As for why the insurance guys are paying...it isn't because of the > > > cost of inhaled steroids; that is minor compared to the cost of > > > Xolair. The real savings will be in less hospital time for the severe > > > asthmatics. One day in hospital is a LOT more than few months of > > > Xolair! > > > > > > Feel free to ask questions about my treatment; I have had very severe > > > asthma all my life and had pretty much all the various therapies at > > > various times and I am happy to share what I *think* I know<vbg>. > > > > > > P. Quote Link to comment Share on other sites More sharing options...
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