Re: Time of day, Prednisone

[Guest guest]

The medical standard is that oral steroids should be taken in the

morning (before or at breakfast time) because of the timing of the

adrenal glands normally producing cortisol. The adrenal glands will

produced less or not produce cortisol when one is on prednisone for

more than a few days, so it's generally understood that there will be

less interference with adrenal function and fewer side effects if one

takes pred in the morning.

That said, prednisone doesn't last 24 hours. I had one allergist who

told me to take 10mg three times a day when I needed pred for three

days. I've taken up to 40mg in the am and another 10 or 15 at night

if I'm at trouble, but it does mess with tapering off it.

In the last couple of years I've started taking 2 puffs of Advair 500

at night rather than take extra oral prednisone. THat seems to help.

Of course, that also means I get an extra dose of serevent, which may

help as well.

I would recommend anyone consult his/her doctor before taking

medicine " off label " or in different quantities or times as prescribed.

Addy

--- In , " ronaldcrpntr " <cowtrail@c...>

wrote:

> Has anyone noticed if there was any difference in functioning,

depending on what time of

> day you take your Prednisone, morning or evening?

> Ron

[Guest guest]

It's nice to know about the adrenal gland and why you should take it

during the day..the reason I always wanted to take it during the day is

because it tended to mess with my sleep patterns and with being sick

that is the last thing you need to be is sleep deprived. So taking it

first thing in the morning was the best so by the end of the day it was

pretty well gone. Though at the moment I am taking half a dose a day in

the am and the other later in the afternoon, so I have all day

protection. I just make sure the lower dose is the evening dose and

that I take it around 4-5 in the afternoon so it doesnt affect night

time overly much.

Thanks for everyones input on this site, it is EXTREMELY helpful.

--- In , " ronaldcrpntr " <cowtrail@c...>

wrote:

> Has anyone noticed if there was any difference in functioning,

depending on what time of

> day you take your Prednisone, morning or evening?

> Ron

[Guest guest]

Same here. I once did split-day dosing but that just

made the side effects worse (the puffy knee syndome)

Alternate day dosing (a big one day 1 and less day 2)

has also been done. I did it for a while but it is

rougher on the old body....

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