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Re: Bound IgE question

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Hi Homer. I don't know enough about the way Xolair works to give you an

educated answer on this. And, while I understand your theory, because it

seems to make sense... the part of me that always ends up in respiratory

arrest and in an ambulance says it's NEVER wise to purposely expose yourself

to something that is a known allergy. Might want to speak with your doc

before you experiment with this!

Take care, Breathe easy!

-------Original Message-------

From: HomerSwei

Date: 04/19/05 18:07:46

Subject: [ ] Bound IgE question

All,

Not sure if anyone knows the answer but... I understand there is bound

and free IgE. Xolair is supposed to interact with the free IgE making

it unavailable to bind with the mast cells (or something like that).

If this is true, can we accelerate the xolair process by frequently

exposing ourselves to whatever is making us allergic during the first

few months of therapy? I mean once all the mast cells are released

there shouldn't be anything more loaded mast cells left. Just a

thought.

Homer

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No, I don't think it works that way. What my doctor said that we

hope for is that Xolair will bind to the IgE and that our bodies

will stop making IgE or make less of it.

Addy

--- In , " HomerSwei " <homerswei@y...>

wrote:

>

>

> All,

>

> Not sure if anyone knows the answer but... I understand there is

bound

> and free IgE. Xolair is supposed to interact with the free IgE

making

> it unavailable to bind with the mast cells (or something like

that).

> If this is true, can we accelerate the xolair process by

frequently

> exposing ourselves to whatever is making us allergic during the

first

> few months of therapy? I mean once all the mast cells are

released

> there shouldn't be anything more loaded mast cells left. Just a

> thought.

>

> Homer

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Guest guest

Our bodies continually make IgE and Mast cells, Basophils and Eosinophils. The

IgE that are bound, are bound until they die. The free IgE is made upon

exposure to our allegens. Protecting your matress, pillows etc with dust mite

proof covers if you are allergic to dust mites helps. If you are allergic to

inhalants, you are exposed when the new grasses grow, trees become alive in

spring or flowering plants pollenate. Minimizing the exposure by keeping doors

and windows closed, changing air filters monthly etc...helps.

__________________________________________________

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  • 2 weeks later...
Guest guest

Hey --

Although I'm just finishing my freshman year of college -- I am

pre-med and my bio teacher this semester focused a lot on the immune

system -- in theory exposing yourself to your allergens would

increase the effectiveness/rate of effectiveness of the xolair --

however I think that doing that would put a lot of stress on your

immune system -- which obviously since you're on xolair, is already

doing more than it should have to. So, no, I don't think that

exposing yourself to your allergens on purpose to increase the

effectiveness of xolair would be a good idea because the immune

system would be fighting against itself to ward off your allergens

while dealing with the xolair and I just think you would complicate

things further. Again, I am just starting out, but thats my opinion :)

Meagan

--- In , " HomerSwei " <homerswei@y...>

wrote:

>

>

> All,

>

> Not sure if anyone knows the answer but... I understand there is

bound

> and free IgE. Xolair is supposed to interact with the free IgE

making

> it unavailable to bind with the mast cells (or something like

that).

> If this is true, can we accelerate the xolair process by frequently

> exposing ourselves to whatever is making us allergic during the

first

> few months of therapy? I mean once all the mast cells are released

> there shouldn't be anything more loaded mast cells left. Just a

> thought.

>

> Homer

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