Joint Pain

[Guest guest]

Has anyone experienced this? A few days after my first shot, I

developed joint and muscular pain, mostly in my legs and feet. It was

so uncomfortable that it kept me awake at night. By the time of my

second shot, two weeks, it had begun to ease up. I mentioned it to my

allergist, and he said it was a side effect -- arthralgia --

arthritic pain without the actual arthritis. A few days after my

second shot, the pain in my feet was so severe that I had to curtail

my gym activities. Walking was an arduous ordeal,, no matter what

kind of shoes I wore. As of this past Saturday, all pain has gone

away, and my feet and legs are normal.

I'm willing to hang in there with the Xolair, because I feel great,

asthamtically speaking, and I'm hoping that as time goes on and my

body adjusts, that these adverse reactions will become fewer and less

severe.

Has anyone had a similar experience?

Amirh

[Guest guest]

I am taking 150 mg. every 2 weeks. This is the first time joint pain has

shown up in over 3 years. I have had and still get headaches from time to time

with the shot. Normally I have a day or two after the shot I don't feel

like myself. I use to be on 300 mg. once a month but had so much pain - which

was totally different from this joint pain. They switched me to 150 mg every

other week and it has been better. The side effects have been some what mild

since I went to every 2 weeks. I have been very determined to stick with

Xolair because of how bad I was without it.

Suzanne

************************************** See what's free at http://www.aol.com.

[Guest guest]

Smart thinking to go to 150mg every two weeks. I would say that

since you saw some improvement in side effects so quickly, that

obviously Xolair is a (if not the) culprit in what's going on with

you as far as the pain. It could be a combination of factors which

includes Xolair. I hope you find out what exactly is going on. I

certainly understand choosing Xolair and a serious side effect over

no Xolair. Each of us has to make our own risk/benefit analysis,

but I know there are some of us who have been so at risk and so

overmedicated due to our severe allergic asthma, that we will do

almost anything to breathe and lower our pred dosages. It is a

terrible place to be, but less terrible than before they discovered

the science behind Xolair. If so many of us are seeing improvement

now, just think of where we will be in another ten years.

Keep hanging in there and working with your docs - leave no stone

unturned!

Addy

Group co-owner

>

> I am taking 150 mg. every 2 weeks. This is the first time joint

pain has

> shown up in over 3 years. I have had and still get headaches

from time to time

> with the shot. Normally I have a day or two after the shot I

don't feel

> like myself. I use to be on 300 mg. once a month but had so much

pain - which

> was totally different from this joint pain. They switched me to

150 mg every

> other week and it has been better. The side effects have been

some what mild

> since I went to every 2 weeks. I have been very determined to

stick with

> Xolair because of how bad I was without it.

>

> Suzanne

>

>

>

> ************************************** See what's free at

http://www.aol.com.

>

>

>

[Guest guest]

I am concerned that the talk of joint pain would put people with

severe allergic asthma off of Xolair.

So I thought I would put my own experience forward.

Each time I was slowly taken off of oral steroids I suffered the

most dreadful joint pains, it felt that my bones were throbbing all

the time through all of my body but more severly in my hips and

legs.

When I started Xolair in 2001 as a trial I was then able to again

slowly come off of oral steroids but again went through the most

awful joint pain.

However this slowly improved to the point I am now free of pain and

have been for a long time.

I know that having high doses of oral steroids which I mainly

controlled myself had a detrimental effect on my body.

Three years ago I developed a chest infection and my Doctor

prescribed oral steroids again, within two days all the pain came

back. I stopped the stoids and have never taken them again.

I think the difficulty is that haveing taken steroids for 40years

has permently damaged me. I have otherwise never flet so well and

from going to hospital and needing to be on a life support machine

having suffered 4 cardiac arrests and my four small children coming

to say goodbye I have not been admitted to hospital because of

asthma once since taking Xolair.

This medicine is my life line and I live knowing that I will not die

of an asthma attack because of it.

It really should only be used to treat severe allergic asthma and I

like MommaA agree the benefits far outweigh any possible side

effects. I would most likely have died by now without it and having

seen my father die of an asthma attack at 61 I know I shall continue

to take it all the time I can.

Thanks Novartis for Xolair.

>

> Group,

>

> Joint pain has so many facets and factors...That being said,

those of us on evil candy & coming off will feel fatigue, joint

pain, have swelling, maybe be lethargic (having no energy), have

problems with glucose regulation and many more irritating problems.

Chronic steroid use causes bone necrosis (bone death) thats why so

many asthmatics have hip & knee & other joint replacements. The

barometric pressure can do a number on our lungs but also causes

swelling in joints, hence joint discomfort. More people complain of

joint pain/discomfort in the Spring & Summer because of the

barometric pressure swings. Those of us who are not teenagers will

have some degree of arthritis from joint damage from normal wear &

tear on our bodies. Falling off roller skates, bicycles, swinging

golf clubs, playing basketball...all adds up over the years.

>

> So, for more reasons than I have listed, you could have joint

pain. The mechanism of action with Xolair doesn't have any reason

to cause joint pain. If you are experiencing joint pain and it is

much worse than before you started Xolair, see a physician. If the

pain is so bad it outweighs the benefits of Xolair speak to your

physician about stopping Xolair. Personally, I have asked this

question to hundreds or thousands of Xolair users " Does this problem

(whatever they complain about) cause enough psychological, physical

or emotional pain that you would think about stopping the Xolair

when the benefits of its use outweigh the problem? " 99.9% of the

people I ask that say " no " . Paraphrasing 'The benefit of Xolair &

my life improvement on Xolair outweigh stopping it'. To them I say -

" great, enough said " . To the people I have had who stop Xolair for

reasons other than money, I say " I am sorry you see this problem as

a reason to stop Xolair, and I hope you find

> something that works as well or better for you " , " New research is

coming out all the time. "

>

> Xolair is a new generation of drug treatment. For moderately

severe to severe asthmatics it is a way to stay out of the

hospital, out of the physicians office every week, a way to increase

quality of life, and eventually decrease chronic medications. There

will always be nay-sayers to anything. You are the only ones who

can say " The joint pain is more bothersome and taking an anti-

inflammatory or something else the Physician prescribed is more

psychologically upsetting than the benefit of the Xolair " . We are

each adults and have to make up our own minds. Personally I see the

benefits of Xolair many many times every day.

>

> By the way, Mothers against asthma, are the group that

produced 'Asthma for Dummies' book. They have a website you may be

able to order them from.

>

> Pat

>

>

>

> ---------------------------------

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