I asked a doctor friend of mine

[Guest guest]

who has experience in both clinical and research about the Xolair box

warning. She said that anyone who has been taking Xolair successfully

without any type of reaction is highly unlikely to experience a severe

reaction due to xolair. She also questioned the likelihood of Xolair

really being the cause of any of the reported anaphylactic reactions

because the patient population is one that is more likely than other

populations to experience severe allergic reactions from any number of

causes AND because of all the unbound IgE that Xolair patients have in

their systems each time they receive their Xolair shots. (The unbound

IgE just waiting around for an allergen to give it an excuse to bind

to the mast cell before the Xolair has a chance to do its job.)

Also, from what Doug and I have been reading, the risk of anaphylactic

shock is no greater now than it was before. The risk percentage has

remained the same from what they found in the clinical trials - no

more no less, and so the FDA has asked Genentech to post it on the

label. That said, anyone who has not yet discussed this issue with

their own physician should do so, of course.

Take care all,

Addy

Group co-owner

IgE in the high 700s

Happy Xolair patient