Re: What happened

February 8, 2007

>

> Has anyone had relatively upleasant reaction to first treatment (2-

1/2

> doses)of Xolair? The morning after my first treatment, I had total

> blocking of my nasal passages, tremendous pressure all around that

> area, wheezing, sore and swollen throat, difficulty swallowing and

> labored breathing. Was sent to emergency at hosp. where I received

> injection of 120 mg of prednisone and 50mg of benadryl. Prednisone

> injection felt like someone shot me in the arm with a gun and is

still

> sore 12 hrs.later but it seems to be doing the job.

>

> Has anyone else had a reaction like this, and if so, was it just a

> first-time anomaly, or did it cause discontinuance of the program?

>

> I'm currently waiting for doc to get back to me re the reaction.

>We have a patient that has stated that her last 3 injections she tend

to develope large locale reactions, about 2-3 hours post Xolair

injection.We did not give her last injection until she saw our main

provider. After our doctor reviewing medical records he stated to

continue with the treatment. we make sure that we continue to

administer the injection very slow and have the patient wait 30min. At

this point we are not to sure if the patient is have a sever reaction

to the drug.we will continue to monitor this patient very close.

February 8, 2007

I cannot remember that we've had more than a handful of posts where

someone became ill following their first treatment. I can't remember

anyone discontinuing it. You might look through past posts

under " first shot " or " first treatment. " This is a high risk group for

upper respiratory stuff as it is.

Addy

Group co-owner

>

> Has anyone had relatively upleasant reaction to first treatment (2-

1/2

> doses)of Xolair? The morning after my first treatment, I had total

> blocking of my nasal passages, tremendous pressure all around that

> area, wheezing, sore and swollen throat, difficulty swallowing and

> labored breathing. Was sent to emergency at hosp. where I received

> injection of 120 mg of prednisone and 50mg of benadryl. Prednisone

> injection felt like someone shot me in the arm with a gun and is

still

> sore 12 hrs.later but it seems to be doing the job.

>

> Has anyone else had a reaction like this, and if so, was it just a

> first-time anomaly, or did it cause discontinuance of the program?

>

> I'm currently waiting for doc to get back to me re the reaction.

>

February 8, 2007

Yesterday I had my 7th zolair shot. The shot I had in January was not

administered by my regular nurse. The shot hurt, I had a big bruise and I had a

knot there for a few days. The bruise lasted the better part of a week. When I

told my nurse about it, her comment was they had other patients who had

complained about the same nurse and the way she gave the xolair shots. I also

told her that I thought she injected the xolair rather quickly compared to the

way it was usually administered. Then she told me that it was very important

for it to be administered very slowly--and that is the way she does it. I never

have a bruise and I never have a knot when she does the injection.

I have two questions about the injection that seemingly caused such a

reaction. What do you mean by 2 1/2 treatments? (I get 1 shot once a

month--the lowest dose.) I am not a nurse, a doctor, nor an expert in any field

of medicine, but is there anyone else who gets this much all at once?

The second question I have is: how slowly was this shot administered? There

are about 60 xolair patients in the clinic where I get my shot and the nurse

told me that they have had only one patient who had an adverse reaction and that

was a very mild reaction. The only other problem is making sure all of the

nurses administer the xolair very slowly and in the right place! This clinic

has seen remarkable results in their patients, very similar to many of the

stories related here.

One other side comment--several months ago, one of the nurses mentioned to me

that they had spent one full day at a xolair workshop/clinic, learning as much

as they could about the drug. That made me feel good!

I hope that your doctor can help you determine whether your reaction was

actually from the xolair or from something that was already at work in your

system.

Oh--one other thing I want to restate: everyone reacts differently to the

xolair. Some people begin to feel relief right away. For others, relief comes

after the third or fourth shot; for others it takes a whole year. For others,

the relief comes very slowly over a longer period and it is only by looking back

that one begins to see progress with the xolair, such as fewer uses of steroids,

fewer needs for the albuterol or neb, longer periods of free breathing, and

fewer trips to the emergency room or hospital stays. Only you and your doctor

can decide about continuing the xolair, but if your doctor thinks it will help

you, then be patient and give it a chance to work.

I just thought of something else: the nurse told me they had one patient who

had to stop his xolair shots because of his insurance and his asthma has

gradually gotten worse again, whereas on the xolair he had begun to experience

relief from severe attacks. Sad that the insurance and lack of money is keeping

this man from getting his shots. The clinic did try to get him some help. I

think they are still working on it.

HAVE A GREAT DAY EVERYONE. AFTER HAVING A BEAUTIFUL DAY YESTERDAY, WE HAVE

ANOTHER CLOUDY, MISTY DAY WITH A COOL FRONT SUPPOSEDLY MOVING IN THIS MORNING!

I PLAN TO HAVE A GREAT DAY ANYWAY!

REMEMBER: TALK WITH YOUR DOCTOR. THE OPINIONS EXPRESSED HERE ARE THOSE OF

THE WRITER, NOT A DOCTOR OR A NURSE OR A PARA-MEDICAL PERSON.

joannnana <joannnana@...> wrote:

--- In , " Terry " <onabeach@...>

wrote: