Re: Wow! Feel Worse but FEV1/I Better! Follow up Tests on Xolair

[Guest guest]

It took me about 4 months on Xolair before my allergic sinuses

started to see improvement and I could start cycling of prednisone.

It varies a lot from one person to another; we don't really know why.

Hang in there.

Addy

Group co-owner who's had significant sinus improvement thanks to

Xolair.

--- In , SD Designer <instdesgn1@...>

wrote:

>

> Have had 3 Xolair series of shots so far (1-1/2 months) and

returned to pulmo today for follow up. I've been having a cold or

flu and feeling terrible - sore throat, tongue, congestion, runny

nose, heavy mucous, fatigued, coughing, difficulty sleeping, etc. for

a week. All of late winter and spring have felt bad. IgE was 350

last fall.

>

> She did another PFT and despite and yucky condition my FEV1/I

increased from 69.53, % PRED 84.6 in Oct 2006 to 72.90 % Pred 88.7

today! I think it's the antibiotic I was on for 3 days

(zithromyacin - 3 pills work for 10 days) but she thinks it's the

Xolair! She said I was looking for a miracle and she's right - or

just feeling good for a change and I sure don't now! I really do

like the pulmo though.

>

> If Xolair was helping wouldn't I feel better? The general

feeling has always been that my chronic sinus problems are basically

allergy and from allergy I quickly go to infection.

>

> I know that Xolair was reported to cause headaches and sore

throat and sinus infection in around 20% of patients but because I

had this going on before Xolair I told her I don't think it has

anything to do with it.

>

> Anyone else had this experience? Could it be a fluke just from

one time to another? I would think, though, that w/a cold it would

be worse.

>

> My pulmo also ordered CBC and liver function tests and tsh and

some blood chemistry stuff too. I assume this is what is recommended

while on Xolair? No complaints here - I'm glad she's doing it as

I've had a lot of stuff wrong.

>

[Guest guest]

SD - my pulmonologist told me at the outset that if I told him I had

improved before a year was up, he wouldn't believe me. I'd like to think

I'm better, but if I forget my Foradil and Pulmicort, I know it that night.

I still wheeze a bit during the day, but it's those clicks, rattles and

weird symphony of various wheeze tones at night in bed that drove me nuts.

I don't have much of that now.

Terry

----- Original Message -----

From: SD Designer

Sent: Tuesday, April 24, 2007 10:11 PM

Subject: [ ] Wow! Feel Worse but FEV1/I Better! Follow up Tests

on Xolair

Have had 3 Xolair series of shots so far (1-1/2 months) and returned to

pulmo today for follow up. I've been having a cold or flu and feeling

terrible - sore throat, tongue, congestion, runny nose, heavy mucous,

fatigued, coughing, difficulty sleeping, etc. for a week. All of late winter

and spring have felt bad. IgE was 350 last fall.

She did another PFT and despite and yucky condition my FEV1/I increased

from 69.53, % PRED 84.6 in Oct 2006 to 72.90 % Pred 88.7 today! I think it's

the antibiotic I was on for 3 days (zithromyacin - 3 pills work for 10 days)

but she thinks it's the Xolair! She said I was looking for a miracle and

she's right - or just feeling good for a change and I sure don't now! I

really do like the pulmo though.

If Xolair was helping wouldn't I feel better? The general feeling has

always been that my chronic sinus problems are basically allergy and from

allergy I quickly go to infection.

I know that Xolair was reported to cause headaches and sore throat and

sinus infection in around 20% of patients but because I had this going on

before Xolair I told her I don't think it has anything to do with it.

Anyone else had this experience? Could it be a fluke just from one time to

another? I would think, though, that w/a cold it would be worse.

My pulmo also ordered CBC and liver function tests and tsh and some blood

chemistry stuff too. I assume this is what is recommended while on Xolair?

No complaints here - I'm glad she's doing it as I've had a lot of stuff

wrong.