Guest guest Posted August 25, 2000 Report Share Posted August 25, 2000 Laurie, It is true that glutathione is needed to detox mercury from the body. I regard a high mercury reading in hair analysis as evidence that the particular PWC is in what I call the main subset, i.e., the one that is caused by glutathione depletion. These are the people who I believe will be helped by ImmunePro and other nondenatured whey protein products. Taking N-acetylcysteine (NAC) is another way to build glutathione, since it supplies cysteine, which is usually the limiting substrate for glutathione synthesis. However, it has been argued by Dr. Bounous, the developer of Immunocal, that it is not as good as whey. I don't understand the pros and cons of this yet. Dr. Quig of Doctor's Data Laboratories recommends that the NAC dose be limited to 200 to 300 mg per day, together with a high protein diet, if a person has a big mercury load. The reason he gives is that higher dosages of NAC under this circumstance can move mercury from other parts of the body into the brain, rather than eliminating it from the body. Rich > Has anyone tried this? From http://www.nutritionfocus.com > > " DESCRIPTION > N-acetyl cysteine is derived from cysteine found in food and > synthesized in the body. It helps the body synthesize glutathione. > > ACTIONS > Antidote (acetaminophen poisoning), antioxidant, bronchomucolytic, > corneal vulnerary, expectorant, helps maintain levels of glutathione, > mucolytic. > > INDICATIONS > Acetaminophen poisoning, asthma, bronchitis, emphysema, environmental > toxins, HIV1, heart disease, respiratory disorders. > REFERENCES > 1. de Quay B., Malinverni R., Lauterburg B.H. Glutathione depletion > in HIV-infected patients: role of cysteine deficiency and effect of > oral N-acetylcysteine. AIDS 1992; 6: 815-819. " > > And from > http://www.tyler-inc.com/detox.htm > This is a description of their product, and so it doesn't give any > information to back up its statement...the usual thing to sell the > item. The Tyler line is sold by Modern Herbalist > http://www.modernherbalist.com > and I get 10 undecenoic acid from them, Formula 722, which is very > good, if that means anything about the tyler item. The reason I > included it in this post is the statement about mercury toxicity > occuring through intracellular glutathione depletion. Comments? > > " Mercury Detox - No. 703 - 60 caps > Contains specific nutrients and cofactors utilized by detoxification > pathways involved with mercury elimination. Sources of mercury > exposure include dental amalgam, contaminated fish, soil, water and > other environmental sources. Mercury toxicity occurs primarily > through intracellular glutathione depletion and oxidative damage. N- > Acetyl-L-Cysteine has been shown to increase both intracellular and > mitochondrial glutathione levels, and to exhibit chelating effects on > mercury and other heavy metals. Selenium has been shown to take part > in mercury detoxification through competition for binding sites, > formation of inactive mercury-selenium compounds and prevention of > oxidative damage. " > > Laurie Lassesen Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 25, 2000 Report Share Posted August 25, 2000 Laurie, I have tried NAC - it made me really sick - no doubt about it. It depends on how well you tolerate sulfur type substances which are the Hg chelators. These worlds are crossed and welcome to them! Some people do really really well with NAC - it is in alot of holistic dentists and mds protocols prior to amalgam removal as well as after. Sufur intolerance, general liver function can be determined by Great Smokies Comprehensive Liver Detox Test one of the challenges is acitominaphen...) . Will show where one is weak - phase 1, phase 2 etc in detail. Hope this helps some. > Has anyone tried this? From http://www.nutritionfocus.com > > " DESCRIPTION > N-acetyl cysteine is derived from cysteine found in food and > synthesized in the body. It helps the body synthesize glutathione. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 25, 2000 Report Share Posted August 25, 2000 People interested in mercury detox via cystein should check out this article by Dr. Quig at Http://www.thorne.com/altmedrev/fulltext/tox3-4.html Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 25, 2000 Report Share Posted August 25, 2000 Thanks for the responses on this. I am taking Immunepro, so maybe I shouldn't try adding anything else for this. I strongly suspect that mercury toxicity has been/is a problem for me. I've had all my amalgam removed, by a moderately adequate protocols, but I had to replace it with crowns, because there was so little emanel left on my teeth - it was mostly amalgam (yipes). I am hesitant to do anything drastic about mercury though, because my instincts (for what they are worth) tell me that my body is already busy enough, with flushing toxins from dying mycoplasmas. I admit to wishing fervently to know about the mercury toxicity and getting it dealt with though. Must be patient... Thanks again, Laurie Lassesen Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 25, 2000 Report Share Posted August 25, 2000 Hmmm...The bit about limiting NAC if you have a big mercury load is definitely food for my thought, as I am taking 2,400 mg/day of NAC. A level of 2000-4000mg/day is recommended on the supplement sheet I got from my doctor, and she mentioned NAC specifically at my last appointment as especially important for me to be taking. I don't know what my mercury load is, though I certainly have a significant amount of amalgam fillings and I eat a lot of fish, so it might be high. Maybe I missed this elsewhere (can't get through more than a small percentage of postings to the list), but is there a URL where more info is available on getting the hair analysis done? >From: vankonynenburg1@... >Reply-egroups >egroups >Subject: Re: N-Acetyl-L-Cysteine >Date: Fri, 25 Aug 2000 17:12:21 -0000 > >Laurie, > >It is true that glutathione is needed to detox mercury from the body. >I regard a high mercury reading in hair analysis as evidence that the >particular PWC is in what I call the main subset, i.e., the one that >is caused by glutathione depletion. These are the people who I >believe will be helped by ImmunePro and other nondenatured whey >protein products. > >Taking N-acetylcysteine (NAC) is another way to build glutathione, >since it supplies cysteine, which is usually the limiting substrate >for glutathione synthesis. However, it has been argued by Dr. >Bounous, the developer of Immunocal, that it is not as good as whey. >I don't understand the pros and cons of this yet. > >Dr. Quig of Doctor's Data Laboratories recommends that the NAC >dose be limited to 200 to 300 mg per day, together with a high >protein >diet, if a person has a big mercury load. The reason he gives is >that >higher dosages of NAC under this circumstance can move mercury from >other parts of the body into the brain, rather than eliminating it >from the body. > >Rich > ________________________________________________________________________ Get Your Private, Free E-mail from MSN Hotmail at http://www.hotmail.com Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 25, 2000 Report Share Posted August 25, 2000 , One place you can look is www.doctorsdata.com There are probably other labs that also do this, but I am familiar with this one. Rich > Hmmm...The bit about limiting NAC if you have a big mercury load is > definitely food for my thought, as I am taking 2,400 mg/day of NAC. A level > of 2000-4000mg/day is recommended on the supplement sheet I got from my > doctor, and she mentioned NAC specifically at my last appointment as > especially important for me to be taking. > > I don't know what my mercury load is, though I certainly have a significant > amount of amalgam fillings and I eat a lot of fish, so it might be high. > Maybe I missed this elsewhere (can't get through more than a small > percentage of postings to the list), but is there a URL where more info is > available on getting the hair analysis done? > > > > >From: vankonynenburg1@l... > >Reply-egroups > >egroups > >Subject: Re: N-Acetyl-L-Cysteine > >Date: Fri, 25 Aug 2000 17:12:21 -0000 > > > >Laurie, > > > >It is true that glutathione is needed to detox mercury from the body. > >I regard a high mercury reading in hair analysis as evidence that the > >particular PWC is in what I call the main subset, i.e., the one that > >is caused by glutathione depletion. These are the people who I > >believe will be helped by ImmunePro and other nondenatured whey > >protein products. > > > >Taking N-acetylcysteine (NAC) is another way to build glutathione, > >since it supplies cysteine, which is usually the limiting substrate > >for glutathione synthesis. However, it has been argued by Dr. > >Bounous, the developer of Immunocal, that it is not as good as whey. > >I don't understand the pros and cons of this yet. > > > >Dr. Quig of Doctor's Data Laboratories recommends that the NAC > >dose be limited to 200 to 300 mg per day, together with a high > >protein > >diet, if a person has a big mercury load. The reason he gives is > >that > >higher dosages of NAC under this circumstance can move mercury from > >other parts of the body into the brain, rather than eliminating it > >from the body. > > > >Rich > > > ______________________________________________________________________ __ > Get Your Private, Free E-mail from MSN Hotmail at http://www.hotmail.com Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 25, 2000 Report Share Posted August 25, 2000 on 8/25/00 1:42 PM, Laurie L. at laurie@... wrote: > Thanks for the responses on this. I am taking Immunepro, so maybe I > shouldn't try adding anything else for this. I strongly suspect that > mercury toxicity has been/is a problem for me. I've had all my > amalgam removed, by a moderately adequate protocols, but I had to > replace it with crowns, because there was so little emanel left on my > teeth - it was mostly amalgam (yipes). I am hesitant to do anything > drastic about mercury though, because my instincts (for what they are > worth) tell me that my body is already busy enough, with flushing > toxins from dying mycoplasmas. I admit to wishing fervently to know > about the mercury toxicity and getting it dealt with though. Must be > patient... Hi Laurie, My EI doc has me convinced that mercury detoxification is extremely important to anyone who has/had several amalgams. Mine have been removed but it's unlikely that the mercury has gone anywhere. The only way to really determine mercury toxicity is to do a DMPS(?) challenge. Hair analysis can only indicate whether or not one is actively excreting mercury--i.e., if a lot of mercury is found in the hair then it means one is actively eliminating it. But hair mercury levels tell us nothing about mercury that may be in the CNS, muscles, connective tissue, etc. My doc recommends the protocol suggested by Dr. Mercola http://www.mercola.com , which involves: liquid minerals, vitamin C infusions, large doses of Chlorella, Cilantro, MSM, alpha lipoic acid... It is a very involved process that gets expensive. I'm very seriously considering it, though. Hud Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 25, 2000 Report Share Posted August 25, 2000 on 8/25/00 2:35 PM, Scherffius at cfids_ex@... wrote: > Hmmm...The bit about limiting NAC if you have a big mercury load is > definitely food for my thought, as I am taking 2,400 mg/day of NAC. A level > of 2000-4000mg/day is recommended on the supplement sheet I got from my > doctor, and she mentioned NAC specifically at my last appointment as > especially important for me to be taking. > > I don't know what my mercury load is, though I certainly have a significant > amount of amalgam fillings and I eat a lot of fish, so it might be high. > Maybe I missed this elsewhere (can't get through more than a small > percentage of postings to the list), but is there a URL where more info is > available on getting the hair analysis done? , As I just mentioned in a previous post, hair analysis is useless for measuring mercury load. High mercury levels in the hair simply means one is excreting mercury. Also, there is definitely reason to be concerned about taking large doses of NAC. Nearly all reputable CFIDS drs. warn of its potential toxicity. NAC is one that you have to be very careful with, although it apparently can do wonders in some cases. Be careful! Hud Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 25, 2000 Report Share Posted August 25, 2000 I agree that a hair analysis doesn't tell you if you have a problem with mercury, only that you are excreting it. I had hair analyses done for a couple of years, before I knew I had CFIDS. The reports (once every 3-4 months) always showed the mercury to be low, and they always told me that when my body got more healthy, it would begin to release mercury that's likely been stored intracellularly. Unfortunately, the mineral/vitamin program didn't do a lot, I felt somewhat better, but my reports didn't show any dramatic improvement in 2 years, while family members doing the same thing were getting markedly improved results on reports. I still wonder that if I had stayed with it, would this have improved, but perhaps I was just feeding mycoplasmas. I am interested in the idea, that as the body gets a better nutritional balance and is more healthy, that it may naturally chelate some of this. My mother tells me that she chelated her mercury on that program, but the only tests were her hair analyses, which went from low mercury, to high mercury and eventually to low mercury again. My instincts tell me that I must get serious about mercury, but I may wait, and just hope that the whey helps me enough for now. I am flushing toxins as I herx off of the antibiotics (doxycycline and olive leaf) and from antivirals (also olive leaf and elderberry and whey), and also the antifungals, so maybe that's all I can handle. Meanwhile, I think I'll have to educate myself further about mercury toxicity testing and treatments, and I'll have more questions for the group, I'm sure :-) Thanks, Laurie Lassesen Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 24, 2008 Report Share Posted March 24, 2008 hello again,sorry,i keep forgeting things,this is the last can anyone tell me anything about the supplement n-acetyl-l-cysteine,is it ok to take or worthwhile taking or not? thanks very much olwyn Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 24, 2008 Report Share Posted March 24, 2008 > > hello again,sorry,i keep forgeting things,this is the last > can anyone tell me anything about the supplement n-acetyl-l- cysteine,is > it ok to take or worthwhile taking or not? > thanks very much ==>No it isn't worthwhile since this diet provide plenty of amino acids in the meats and eggs. Please re-read the section on Supplements in my article " How to Successfully Overcome Candida " where it explains why you do not take other supplements than those that are listed. The best, Bee Quote Link to comment Share on other sites More sharing options...
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