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Vitamin B

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>

>

> > +++I recommend a vitamin B complex with no extra B6, 50 mg

twice a

> > day so that's not very much.

>

>

> Bee, I also developed b6 toxicity several months ago when taking a

> multi vitamin which had about the same amount of B6 you recommend.

> 50mgs is 2500% of the %DV. That times two and we are getting 5000%

of

> the %DV.

>

> My sister also developed B6 toxicity and is being tested for CMT.

Now

> I'm wondering if I will run into a problem taking the B complex

too.

> I'll wait to see what her results are.

Hi Sandy. See this reference:

http://www.salugenecists.com/genpage.php?tname=nutrient & dbid=108

" Symptoms of vitamin B6 deficiency also manifest in impairments to

the nervous system and the synthesis of red blood cells since this

nutrient plays such a vital role in these processes. Many nerve-

related symptoms can manifest with inadequate consumption of vitamin

B6 with convulsions and seizures being possible adverse events

associated with severe deficiency. Reflecting its importance in the

formation of red blood cells, vitamin B6 deficiency can result in

symptoms of anemia, fatigue and malaise. Hypochromic, microcytic

(pernicious) anemia is the condition associated with anemia that is

exclusively related to vitamin B6 deficiency.

Vitamin B6 interacts with numerous other B-complex vitamins. The

conversion of tryptophan to vitamin B3 (niacin) is dependent upon

vitamin B6. Research focusing on Down's syndrome has shown, for

example, that some of the niacin deficiency problems resolve with the

intake of vitamin B6. Imbalances of vitamin B1 metabolism result in

imbalanced metabolism of vitamin B6 while deficiency of vitamin B6

can also reduce the body's absorption of vitamin B12. Finally, both

vitamins B2 and B3 are necessary for the conversion of vitamin B6

into various different chemical forms.

Causes and symptoms of vitamin B6 toxicity:

While deficiency of vitamin B6 can manifest in nervous system

imbalances, high levels of supplemental vitamin B6 can also cause

these adverse effects. These imbalances do not seem to occur until

supplementation levels exceed 2 grams (2,000 mg) per day. Largely

based upon the concerns for imbalanced nervous system activity, in

1997, the Institute of Medicine at the National Academy of Sciences

set a Tolerable Upper Intake Level (UL) for vitamin B6 of 100

milligrams for adults 19 years and older. "

Vitamin B6 Toxicity from " Government vitamin safety data slanted says

ION (The Institute for Optimum Nutrition): http://tinyurl.com/5vlosy

" The FSA also inaccurately reported the conclusions of our study by

commenting that they " noted sporadic adverse neurotoxic effects in

subjects taking 200 mg per day vitamin B6 for some years " . This was

not the case. In fact our study showed that improvements were

seen: " An analysis of the findings indicated that the dose range of

101 mg - 200 mg (per day) demonstrated statistical significant

improvements in these symptoms (associated with B6 toxicity). "

If you are concerned about taking B complex, you can substitute with

red meat liver or Nutritional Yeast Flakes (ensure it is the Flakes

and not just Nutritional Yeast) - take 2 tbls. per day in water twice

a day.

Bee

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